Journal of Biomedical Engineering and Technology
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Journal of Biomedical Engineering and Technology. 2014, 2(1), 1-4
DOI: 10.12691/jbet-2-1-1
Open AccessReview Article

Interaction of Mobile Telephone Radiation with Biological Systems in Veterinary and Medicine

Ezzatollah Fathi1 and Raheleh Farahzadi2,

1Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz-Iran

2Department of Biochemistry, Faculty of Medical Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran

Pub. Date: January 20, 2014

Cite this paper:
Ezzatollah Fathi and Raheleh Farahzadi. Interaction of Mobile Telephone Radiation with Biological Systems in Veterinary and Medicine. Journal of Biomedical Engineering and Technology. 2014; 2(1):1-4. doi: 10.12691/jbet-2-1-1


Every day, we’re swimming in a sea of electromagnetic radiation produced by electrical appliances, power lines, wiring in buildings, and a group of other technologies that are part of modern life. Cell phones have become a vital part of our lives, and its use is not only restricted to voice conversations but also conveying news, high resolution pictures and internet. During recent years there has been increasing public concern on potential health risks from extremely low frequency electromagnetic fields and radiofrequency/microwave radiation emissions. It is fairly well established that at sufficiently high power levels, radiofrequency and microwave energy can produce deleterious biological effects. Some investigations suggested that these fields may have genotoxic effects and may increase the risk of several cancers and neurological disorders such as Alzheimer's disease. The aim of this review was to evaluate the influence of mobile telephone radiation on biological systems and health. It is concluded that these fields can influence several biological functions of cells and tissues, modulating intracellular reactive oxygen species levels and the cell cycle progression.

electromagnetic waves radiofrequency waves biological systems health

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[1]  Bhat, M.A. “Effects of Electromagnetic Waves Emitted by Mobile Phones on Male Fertility,” Computer Engineering and Intelligent Systems, 4 (3). 2013.
[2]  Orendacova, J., Orendac, M., Racekova, E. and Marsala, J, “Neuorobiological effects of microwave exposure: a review focused on morphological findings in experimental animals”, Archives Italiennes deBiologie, 145. 1-12. 2007.
[3]  Al-Qudsi, F. and Azzouz, S, “Effect of Electromagnetic Mobile Radiation on Chick Embryo Development” Life Science Journal, 9 (2). 2012.
[4]  IARC working group on the evaluation of carcinogenic risks to humans. International agency for research on cancer IARC monographs on the evaluation of carcinogenic risks to humans. IARC Press, France. 80 (27). 2002.
[5]  Yan, J., Dong, L., Zhang, B. and QI, N, “Effects of Extremely Low-Frequency Magnetic Field on Growth and Differentiation of Human Mesenchymal Stem Cells,” Electromagnetic Biol Med, 29. 165-176. 2010.
[6]  Hardell, L. and Sage, C, “Biological effects from electromagnetic field exposure and public exposure standards,” Biomed Pharmacother, 62. 104-109. 2008.
[7]  P, Sowa, “Identification of Impact of Electromagnetic Fields at Low and High Frequency on Human Body,” IJEEE, 6. 219-222. 2012.
[8]  Baharara, J., Moghimy, A. and moosavi, S, “Effect of Cell Phone Radiation (940 MHz) on the Learning and Memory of Balb/c mice,” J Armaghan Danesh, 14 (2). 54-64. 2009.
[9]  Alaa, J., Hamada, A. S. and Ashok, A, “Cell Phones and their Impact on Male Fertility: Fact or Fiction,” The Open Reproductive Science Journal, 5. 125-137. 2011.
[10]  Fernie, K. J. and Reynolds, S. J, “The effects of electromagnetic fields from power lines on avian reproductive biology and physiology: a review,” J Toxocol Envir Health, 8. 127-140. 2005.
[11]  Deepinder, F., Makker, K. and Agarwal, A, “Cell phones and male infertility: dissecting the relationship,” Reprod Biomed Online, 15. 266-70. 2007.
[12]  Habash, R. W. Y, “Bioeffects and therapeutic applications of electromagnetic energy,” Boca Raton: CRC Press. 2008.
[13]  Cleveland, R. F. and Ulcek, J. L, “Questions and answers about biological effects and potential hazards of radiofrequency electromagnetic fields,” OET Bull, 56. 1-36. 1999.
[14]  Lin, J.C, “Early contributions to electromagnetic fields in living systems,” Advances in Electromagnetics Fields in Living Systems, Vol. 1, ed. J.C. Lin (Plenum, New York, 1994) pp. 1-26.
[15]  James, C.L, “Biological aspects of mobile communication fields,” Wireless Networks 3, 439-453. 1997.
[16]  George, D. F., Bilek, M. M. and McKenzie, D. R, “Non-thermal effects in the microwave induced unfolding of proteins observed by chaperone binding” Bioelectromagnetics, 29. 324-30. 2008.
[17]  Dasdag, S., Bilgin, H. M., Akdag, M. Z., Celik, H. and Aksen, F, “Effect of long term mobile phone exposure on oxidative processes and nitric oxide in rats,” Biotechnol & Biotechnol Eq, 22. 992-7. 2008.
[18]  Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T.D., Mazur, M. and Tesler, J, “Free radicals and antioxidants in normal physiological functions and human disease,” Int J Biochem Cell Biol, 39. 44-84. 2007.
[19]  Fröhlich, H, “The biological effects of microwaves and related questions,” Adv Electronics Electron Phys, 53.85-8. 1980.
[20]  Fröhlich, H, “Long-range coherence and energy storage in biological systems,” Int J Quantum Chem, 2. 641-9. 1968.
[21]  Sobczak, A, “Effects of EMF on free radical processes in steelworkers,” J Occupational Health, 44. 230-233. 2002.
[22]  Trosic, I., Pavicic, I., Marjanovic, A.M. and Busljeta, I, “Non-thermal biomarkers of exposure to radiofrequency/microwave radiation,” Arh Hig Rada Toksikol, 63 (1). 67-73. 2012.
[23]  Kundi, M, “The controversy about a possible relationship between mobile phone use and cancer,” J Environ Health Perspect, 117 (3). 316-24. 2009.
[24]  Volkow, N. D., Tomasi, D., Wang, G. J. and et al, “Effects of cell phone radiofrequency signal exposure on brain glucose metabolism,” JAMA, 305 (8). 808-813. 2011.
[25]  Abdel-Rassoul, G., Abou El-Faateh, O., Abou- Salem, E., Michael, A., Farahat, F., El-Batanouny, M. and Salem, E, “Neurobehavioral effects among inhabtants around mobile phone base stations,” Neuro Toxicology, 28. 434-440. 2007.
[26]  Beason, R.C. and Semm, P, “Responses of neurons to an amplitude modulated microwave stimulus,” J Neurosci Lett, 333 (3). 175-8. 2002.
[27]  Lahkola, A., Salminen, T., Raitanen, J., Heinävaara, S., Schoemaker, M., Christensen, H.C. and et al, “Meningioma and mobile phone use-a collaborative case-control study in five North European countries,”Int J Epidemiol, 37 (6). 1304-13. 2008.
[28]  Hardell, L., Carlberg, M., Soderqvist, F. and Hansson, M.K, “Meta-analysis of long-term mobile phone use and the association with brain tumours,” Int J Oncol, 32 (5). 1097-103. 2008.
[29]  Ahlbom, A., Feychting, M., Green, A., Kheifets, L., Savitz, D.A. and Swerdlow, A.J, “Epidemiologic evidence on mobile phones and tumor risk: a review,” Epidemiology, 20 (5). 639-52. 2009.
[30]  Firouzabadi, S., Jadidi, M. and Bolouri, B, “Evaluation Of The Effect Of 950 Mhz Waves Of Gsm Mobile Phone System On Acquisition Phase Of Rat’s Spatial Memory In Morris Water Maze,” J Koomesh, 2005; 7 (1-2): 19-25.
[31]  Bonnefont, A., Hirbec, H., Bonnefont, X., Privat, A., Vignon, J., Seze, R. and Hirbec, H, “Acute exposure to gsm 900-mhz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain,” Neurobiology of Disease, 17. 445-454. 2004.
[32]  Xu, S., Zhou, Z., Zhang, L. and et al, “Exposure to 1800 MHZ radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons,” Brain Research, 1311. 189-196. 2010.
[33]  Zhao, T., Zou, S. and Knapp, P, “Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes,” Neurosci Lett, 412 (1). 34-38. 2007.
[34]  Lai, H. and Singh, N.P, “Magnetic-field-induced DNA strand breaks in brain cells of the rat,” Environmental Health Perspectives, 112 (6). 687-694. 2004.
[35]  Nittby, H., Brun, A., Eberhardt, J. and et al, “Increased blood-brain barrier permeability in mammalian brain 7 days after exposure to the radiation from a GSM-900 mobile phone,” Pathophysiology, 16. 103-112. 2009.
[36]  Awad, S.M. and Hassan, N.S, “Health Risks of electromagnetic radiation from mobile phone on brain of Rats,” J. Appl. Sci. Res, 4 (12). 1994-2000. 2008.
[37]  Komeili, G. H. and Nabizadeh Sarabandi, S, “Studying the Effects of Mobile Phone Waves on Electro Cardiogram Parameters of Students in Zahedan University of Medical Sciences,” Int J High Risk Behav Addict, 1 (2). 75-78. 2012.
[38]  Vignal, R., Crouzier, D. and Dabouis, V, “Effects of mobile phones and radar radiofrequency on the eye,” Pathol Biol, 57 (6). 503-8. 2009.
[39]  Magras, I.N. and Xenos, T.D, “RF radiation-induced changes in the prenatal development of mice,” Bioelectromagnetics, 18. 455-461. 1997.
[40]  Dasdag, S., Oflazoglu, H., Kelle, M. and Akdag, Z, “Efects of microwave on the phagocytic activity of variously treated rat macrophages,” Electro Magnetobiol, 17. 185-94. 1998.
[41]  Jung, A. and Schill, W.B, “Male infertility. Current life style could be responsible for infertility,” MMW Fortschr Med, 142. 31-3. 2000.
[42]  Roosli, M., Michel, G., Kuehni, C.E. and Spoerri, A, “Cellular telephone use and time trends in brain tumour mortality in Switzerland from,” Eur J Cancer Prev, 16. 77-82. 2007.
[43]  Ingole, I.V. and Ghosh, S.K, “Cell phone radiation and developing tissues in chick embryo-a light microscopic study of kidneys,” J. Anat. Soc. India, 55 (2). 19-23. 2006.
[44]  Mahram, M. and Ghazavi, M, “The effect of extremely low frequency electromagnetic fields on pregnancy and fetal growth, and development,” Arch Iranian Med, 16. 221-224. 2013.