International Journal of Hematological Disorders
ISSN (Print): ISSN Pending ISSN (Online): ISSN Pending Website: http://www.sciepub.com/journal/ijhd Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
International Journal of Hematological Disorders. 2015, 2(1), 1-3
DOI: 10.12691/ijhd-2-1-1
Open AccessCase Report

Isolated Primary Malignant Lymphoma Arising from the Skull Base

Btissaam. Belhoucha1, , Lahcen. Aderdour1, Skoumi Mohamed2, Sara Belghmidi3, Youssef. Rochdi1, Aniba Khalid2, hajji btissam3, Hassan. Nouri1, A Moutaouakil3, Ait Benali Said2 and Abdelaziz. Raji1

1Department of ENT, CHU Med VI, Marrakech 2360, Morocco

2Department of Neurosurgery University hospital Mohammed VI, Marrakesh, Morocco

3Department of ohtalmology, CHU Mohammed VI, Marrakech, Maroc

Pub. Date: January 04, 2015

Cite this paper:
Btissaam. Belhoucha, Lahcen. Aderdour, Skoumi Mohamed, Sara Belghmidi, Youssef. Rochdi, Aniba Khalid, hajji btissam, Hassan. Nouri, A Moutaouakil, Ait Benali Said and Abdelaziz. Raji. Isolated Primary Malignant Lymphoma Arising from the Skull Base. International Journal of Hematological Disorders. 2015; 2(1):1-3. doi: 10.12691/ijhd-2-1-1

Abstract

Primary skull base lymphoma is quite rare entity, accounting for 1% - 2% of all skull base tumors. Due to its rarity and its similarity to other tumors skull base lymphoma remains a diagnostic challenge. We present a 3-year-old previously healthy boy presented with blindness and exophtalmos revealing a primary skull base lymphoma. The clinical and the radiological features of the lesion have been described as well as the pathologic findings. Lymphoma, although uncommon, should be included in the differential diagnosis of such neoplasms of the skull base. Early diagnosis and treatment as prompt management are crucial for both a visual and vital prognosis.

Keywords:
Lymphoma skull base optic chiasma Biopsy

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Figures

Figure of 2

References:

[1]  O. Dare, R. V. Datta, T. R. Loree, W. L. Hicks and W. Grand, “Sinonasal Non-Hodgkin’s Lymphoma with Skull Base Involvement,” Skull Base, Vol. 11, No. 2, 2001, pp. 129-135.
 
[2]  Mario Teo1 et al ; Dural Graft-Induced Fibrotic Mass Twelve Years after Successful Treatment of Skull Base Non-Hodgkin Lymphoma Mimicking Recurrence: Case Report and Literature Review; Open Journal of Modern Neurosurgery, 2014, 4, 7-12.
 
[3]  V. W. Tsai, L. Rybak, J. Espinosa, M. J. Kuhn, O. W. Ka-mel, F. Mathews and F. R. Glatz, “Primary B-Cell Lym-phoma of the Clivus: Case Report,” Surgical Neurology, Vol. 58, No. 3-4, 2002, pp. 246-250.
 
[4]  F. J. Hans, M. H. Reinges, K. Nolte, P. Reipke and T. Krings, “Primary Lymphoma of the Skull Base,” Neuro-radiology, Vol. 47, No. 7, 2005, pp. 539-542.
 
[5]  S. Jung, M. Zimmermann and V. Seifert, “Clivus Lym-phoma,” Acta Neurochirurgica, Vol. 146, No. 5, 2004, pp. 533-534.
 
[6]  K. Jaiswal, M. Tripathi, P. S. Chandra, M. C. Sharma and A. K. Maha-patra, “An Unusual Case of Primary Lymphoma of the Skull Base Extending from Cerebellopon-tine Angle to Cavernous Sinus and Orbit. A Case Report,” Journal Neurosurg Science, Vol. 44, No. 3, 2000, pp. 145-148.
 
[7]  Gray RS, Abrahams JJ, Hufnagel TJ, et al. Ghost cell tumor of the optic chiasm: primary CNS lymphoma. J Clin Neuroophthalmol 1989; 9: 98-104.
 
[8]  K. Jaiswal, M. Tripathi, P. S. Chandra, M. C. Sharma and A. K. Maha-patra, “An Unusual Case of Primary Lymphoma of the Skull Base Extending from Cerebellopon-tine Angle to Cavernous Sinus and Orbit. A Case Report,” Journal Neurosurg Science, Vol. 44, No. 3, 2000, pp. 145-148.
 
[9]  H. Oyama, M. Nagane, S. Shibui, K. Nomura and K. Mu-kai, “Skull Base Malignant Lymphoma: A Case Report and Review of the Literature,” Japanese Journal of Cli-nical Oncology, Vol. 22, No. 2, 1992, pp. 131-135.
 
[10]  Bent JP, Hebert, RL, Smith, RJ. Pediatric Neck Neoplasms. In, Pediatric Otolaryngology, RF Wetmore, HR Muntz, TJ McGill, Eds. Thieme Medical Publishers, Inc., New York; 2000: 993-1019.
 
[11]  Elizabeth j. Rosen, md, pediatric head and neck malignancies april 2003, grand rounds presentation, UTMB, dept. Of otolaryngology
 
[12]  Samuelsson, BO, Ridell, B, Rockert, L, et al. Non-Hodgkin Lymphoma in Children: A 20-Year Population-Based Epidemiologic Study in Western Sweden. Journal of Pediatric Hematology/Oncology. Mar/Apr 1999, 21 (2); 103-110.