International Journal of Hematological Disorders
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International Journal of Hematological Disorders. 2014, 1(1), 22-26
DOI: 10.12691/ijhd-1-1-4
Open AccessReview Article

Bleeding Disorders: Insights into Aetiology, Pathogenesis, Diagnosis and Management

Ahmed M Kabel1, 2,

1Department of Clinical Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia

2Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt

Pub. Date: September 29, 2014

Cite this paper:
Ahmed M Kabel. Bleeding Disorders: Insights into Aetiology, Pathogenesis, Diagnosis and Management. International Journal of Hematological Disorders. 2014; 1(1):22-26. doi: 10.12691/ijhd-1-1-4

Abstract

Background: Coagulation plays an important role in haemostasis. Bleeding disorders caused by deficiency of certain coagulation factors such as hemophilia and Von Willebrand disease can affect haemostasis and may endanger life. Aim: To put a focus on the aetiology, pathogenesis, methods of diagnosis and lines of management of bleeding disorders. Conclusion: Bleeding disorders usually result from hereditary deficiency of certain coagulation factors. These disorders often affect lifestyle of the patient and may have serious complications. Further studies are needed to explore the exact pathogenesis of these disorders and new lines of management especially for gene therapy.

Keywords:
hemophilia pathogenesis diagnosis management

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