International Journal of Dental Sciences and Research
ISSN (Print): 2333-1135 ISSN (Online): 2333-1259 Website: Editor-in-chief: Marcos Roberto Tovani Palone
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International Journal of Dental Sciences and Research. 2018, 6(1), 1-5
DOI: 10.12691/ijdsr-6-1-1
Open AccessArticle

Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study

Ozkan Ozgul1, and Selahattin Or2

1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kirikkale University, Kirikkale, Turkey

2Department of Oral and maxillofacial Surgery, Faculty of Dentistry, Ankara University, Ankara, Turkey

Pub. Date: January 09, 2018

Cite this paper:
Ozkan Ozgul and Selahattin Or. Efficacy of NSAID (Lornoxicam) After Impacted Third-Molar Surgery With/Without Conscious Sedation: A Double-Blind Randomized Clinical Study. International Journal of Dental Sciences and Research. 2018; 6(1):1-5. doi: 10.12691/ijdsr-6-1-1


Aim: Pain and swelling following surgery for impacted third molars can be controlled by various methods. This study compared the analgesic and anti-inflammatory efficacy and tolerability of lornoxicam, aspirin and a placebo with and without conscious sedation in impacted mandibular third-molar surgery. Materials and Methods: 60 patients undergoing third-molar surgery were divided into 2 groups of conscious sedation and routine local anesthesia (n=30). Both groups were divided into three subgroups (n=10) that received either Lornoxicam, aspirin, or a placebo postoperatively. Results: In both the conscious sedation and local anesthesia groups, swelling reduction was significantly greater with Lornoxicam compared to aspirin and placebo (p< .05). Pain values were significantly lower for Lornoxicam group compared to both aspirin and placebo groups at 6, 12 and 24 hours postoperatively (p< .05). Conclusion: Conscious sedation resulted less pain and swelling. Moreover, Lornoxicam was found to be an effective analgesic and anti-inflammatory agent for use in conjunction with oral surgery.

conscious sedation third molar surgery NSAID swelling pain clinical research

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