International Journal of Dental Sciences and Research
ISSN (Print): 2333-1135 ISSN (Online): 2333-1259 Website: Editor-in-chief: Marcos Roberto Tovani Palone
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International Journal of Dental Sciences and Research. 2014, 2(5), 106-108
DOI: 10.12691/ijdsr-2-5-1
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Oral Squamous Cell Carcinoma of Palate – A Case Report and Review of Literature

Laliytha Kumar Bijai1, , Philips Mathew2, Venkatesh Jayaraman2 and Ravi David Austin2

1Department of Dentistry, Sree Balaji Medical College and Hospital, Bharath University, Chennai, India

2Department of Oral Medicine and Radiology, Rajah Muthiah Dental College, Annamalai University, Chidambaram, India

Pub. Date: August 28, 2014

Cite this paper:
Laliytha Kumar Bijai, Philips Mathew, Venkatesh Jayaraman and Ravi David Austin. Oral Squamous Cell Carcinoma of Palate – A Case Report and Review of Literature. International Journal of Dental Sciences and Research. 2014; 2(5):106-108. doi: 10.12691/ijdsr-2-5-1


Oral squamous cell carcinoma (OSCC) is a significant public health problem worldwide. More than 95% of the carcinomas of the oral cavity are of squamous cell type, in nature. The development of OSCC is a multistep process requiring the accumulation of multiple genetic alterations, influenced by environmental influences, including tobacco products, alcohol consmption, viral infection, chronic inflammation and also patient's genetic predisposition. Here we present a case of oral squamous cell carcinoma of palate in a 62-year-old male patient.

oral squamous cell carcinoma betel quid carcinogenesis

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[1]  Landis SH, Murray T, Bolden S, Wingo PA, Cancer statistics, 1999. CA Cancer J Clin 1999; 49: 8-31.
[2]  E. Attar, S. Dey, A. Hablas, I. A. Seifeldin, M. Ramadan, L. S. Rozek and A. S. Soliman, “Head and Neck Cancer in a Developing Country: A Population-Based Perspec-tive Across 8 Years,” Oral Oncology, Vol. 46, No. 8, 2010, pp. 591-596.
[3]  C. Scully and J. Bagan, “Oral Squamous Cell Carcinoma Overview,” Oral Oncology, Vol. 45, No. 4, 2009, pp. 301-308.
[4]  Neville BW, Damm DD, Allen CM, et al. Oral & maxillofacial pathology. 2nd ed. Phila., PA: Saunders; 2002; 337-369.
[5]  Jovanovic A, Schulten EA, Kostense PJ, et al. Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma. J Oral Pathol Med 1993; 22: 459-462.
[6]  Pindborg JJ, Reichart PA, Smith CJ, van der Wall I. Histological typing of cancer and precancer of the oral mucosa. 2nd ed. Berlin: Springer Verlag; 1997. p. 10-6.
[7]  J. P. Shah and Z. Gil, “Current Concepts in Management of Oral Cancer-Surgery,” Oral Oncology, Vol. 45, No. 4, 2009, pp. 394-401.
[8]  J. H. Lorch, M. R. Posner, L. J. Wirth and R. I. Haddad, “Seeking Alternative Biological Therapies: The Future of Targeted Molecular Treatment,” Oral Oncology, Vol. 45, No. 4, 2009, pp. 447-453.
[9]  B. J. Braakhuis, M. P. Tabor, C. R. Leemans, I. van der Waal, G. B. Snow and R. H. Brakenhoff, “Second Pri-mary Tumors and Field Cancerization in Oral and Oro-pharyngeal Cancer: Molecular Techniques Provide New Insights and Definitions,” Head and Neck, Vol. 24, No. 2, 2002, pp. 198-206.
[10]  D. Goldenberg, S. Harden, B. G. Masayesva, P. Ha, N. Benoit, W. H. Westra, W. M. Koch, D. Sidransky and J. A. Califano, “Intraoperative Molecular Margin Analysis in Head and Neck Cancer,” Archives of Otolaryngol-ogy—Head and Neck Surgery, Vol. 130, No. 1, 2004, pp. 39-44.
[11]  Silverman S Jr. Demographics and occurrence of oral and pharyngeal cancers. The outcomes, the trends, the challenge. J Am Dent Assoc 2001; 132: 7S-11S.