International Journal of Clinical and Diagnostic Research
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International Journal of Clinical and Diagnostic Research. 2021, 9(1), 1-11
DOI: 10.12691/ijcdr-9-1-1
Open AccessArticle

FETUSES OF MOTHERS WITH HYPERGLYCEMIA FIRST DETECTED IN PREGNANCY HAVE SIGNIFICANT CARDIAC CHANGES

Alagbe Olayemi Atinuke1, , Bello Temitope O2 and Ayoola Olugbemiga3

1Departments of Radiology, LAUTECH Teaching Hospital, PMB 5000, Osogbo, Osun State

2Departments of Radiology, LAUTECH Teaching Hospital, PMB 5001, Osogbo, Osun State

3Department of Radiology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria

Pub. Date: January 15, 2021

Cite this paper:
Alagbe Olayemi Atinuke, Bello Temitope O and Ayoola Olugbemiga. FETUSES OF MOTHERS WITH HYPERGLYCEMIA FIRST DETECTED IN PREGNANCY HAVE SIGNIFICANT CARDIAC CHANGES. International Journal of Clinical and Diagnostic Research. 2021; 9(1):1-11. doi: 10.12691/ijcdr-9-1-1

Abstract

Fetal cardiomyopathy is one of the complications of diabetic pregnancy. World Health Organization (WHO) classified hyperglycemia first detected during pregnancy in to gestational diabetes mellitus (GDM) and diabetes in pregnancy (DIP) based on the severity of hyperglycemia as revealed by the fasting blood sugar. This study aimed at characterizing and comparing the fetal cardiac changes in mothers with GDM and DIP. One hundred and fifty consenting mothers at 32-35 weeks gestation were enrolled in this study and grouped in to GDM, DIP, pre-gestational DM (PDM) and control groups. The basic obstetric and fetal echocardiographic scans were performed on all the participants. The fetuses of mothers with GDM, DIP and PDM groups had significantly thickened end diastolic interventricular septal thickness and end systolic interventricular septal thickness compared to fetuses of mothers in the control group. The mitral and tricuspid E/A were also significantly reduced in the fetuses of mothers in the hyperglycemic group compared to fetuses of mothers in the control group. This study has shown that the higher the level of maternal hyperglycemia the more the severity of fetal cardiac complications. It also showed that hyperglycemia in pregnancy whether symptomatic or not, is associated with significant fetal cardiac changes. Hence, blood glycemic level should be kept within normal range during pregnancy.

Keywords:
Hyperglycemia End diastolic End systolic Interventricular septum Echocardiographic Diabetes

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