International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: http://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2018, 6(3), 87-88
DOI: 10.12691/ijcd-6-3-2
Open AccessArticle

False-negative IgA Anti-tissue Transglutaminase

Nada Boutrid1, 2, , Hakim Rahmoune1, 2 and Mounira Amrane2, 3

1Department of Pediatrics, University Hospital of Setif; Setif 1 University, Algeria

2Genetic, Cardiovascular & Nutritional Diseases Laboratory; Setif-1 University, Algeria

3Central Laboratory, CAC Hospital of Setif; Setif-1 University, Algeria

Pub. Date: January 04, 2019

Cite this paper:
Nada Boutrid, Hakim Rahmoune and Mounira Amrane. False-negative IgA Anti-tissue Transglutaminase. International Journal of Celiac Disease. 2018; 6(3):87-88. doi: 10.12691/ijcd-6-3-2

Abstract

The expanding knowledge about gluten-related autoimmunity led to a serology-based step-wised approach to diagnose celiac disease that might be misleading due to laboratory techniques. We present a rare case associating initial false-negative anti-transglutaminase IgA antibodies while CD was confirmed by IgG anti-transglutaminase and subsequent duodenal biopsy.

Keywords:
celiac disease autoimmunity immunoglobulin A tissue transglutaminase

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