International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: http://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
Open Access
Journal Browser
Go
International Journal of Celiac Disease. 2018, 6(3), 68-70
DOI: 10.12691/ijcd-6-3-8
Open AccessArticle

Celiac Disease and Lactose Intolerance

Lerner Aaron1, 2, , Wusterhausen Patricia2, Ramesh Ajay2 and Matthias Torsten2

1B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, 31096, Israel

2AESKU.KIPP Institute, Wendelsheim, 55234, Germany

Pub. Date: January 04, 2019

Cite this paper:
Lerner Aaron, Wusterhausen Patricia, Ramesh Ajay and Matthias Torsten. Celiac Disease and Lactose Intolerance. International Journal of Celiac Disease. 2018; 6(3):68-70. doi: 10.12691/ijcd-6-3-8

Abstract

Celiac disease and lactose intolerance are nutritional diseases where withdrawal of a specific nutrient is therapeutical. Celiac disease is underdiagnosed while lactose intolerance is over diagnosed, including in naïve or treated celiac patients. The present review highlights myths and realities and revisits common misconceptions in the relationship between celiac disease and lactose intolerance. It is hoped that the care providers will increase the rate of diagnosis of celiac disease, while decreasing the over diagnosis of lactose intolerance for the benefit of the patients.

Keywords:
celiac disease lactose intolerance dairy food hydrogen breath test health promotion

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Lerner A, Jeremias P, Matthias T. The world incidence of celiac disease is increasing: a review. Internat. J. Of Recent Scient. Res. 2015; 7: 5491-5496.
 
[2]  Lerner A, Jeremias P, Matthias T. The world incidence and prevalence of autoimmune diseases is increasing: A review. Internat J Celiac Disease. 2015; 3: 151-155.
 
[3]  Lerner A, Matthias T. Extraintestinal manifestations of CD: Common pathways in the gut-remote organs’ axes. Internat J Celiac Dis. 2017; 5: 24-27.
 
[4]  Lerner A, Matthias T. A Silent or Hypo-symptomatic Disease Can Erupt: Acute Presentations of Celiac Disease. Internat J Celiac Dis 2017; 5: 129-132.
 
[5]  Lerner A, Agmon-Levin N, Shapira Y, Gilburd B, Reuter S, Lavi L, Shoenfeld Y. The thrombophylic network of autoantibodies in celiac disease. BMJ Medicine, 2013,11; 89-95.
 
[6]  Eliyah Livshits O, Shauol R, Reifen R, Matthias T, Lerner A. Can Celiac Disease Present Along With Childhood Obesity? International Journal of Celiac Disease. 2017; 5: 19-23.
 
[7]  Lerner A, Makhoul BF, Eliakim R. Neurological manifestations of celiac disease in children and adults. Europ Neurolog J. 2012; 4: 15-20.
 
[8]  Coucke F. Food intolerance in patients with manifest autoimmunity. Observational study. Autoimmun Rev. 2018; 17: 1078-1080.
 
[9]  Vandenplas Y. Lactose intolerance. Asia Pac J Clin Nutr. 2015; 24 Suppl 1: S9-13.
 
[10]  Di Rienzo T, D'Angelo G, D'Aversa F, Campanale MC, Cesario V, Montalto M, et al. Lactose intolerance: from diagnosis to correct management. Eur Rev Med Pharmacol Sci. 2013; 17 Suppl 2: 18-25.
 
[11]  Deng Y, Misselwitz B, Dai N, Fox M. Lactose Intolerance in Adults: Biological Mechanism and Dietary Management. Nutrients. 2015; 7: 8020-35.
 
[12]  Matthews SB, Campbell AK. When sugar is not so sweet. Lancet. 2000; 355(9212): 1330.
 
[13]  Grimheden P, Anderlid BM, Gåfvels M, Svahn J, Grahnquist L. Lactose intolerance in children is an overdiagnosed condition. Risk of missing intestinal diseases such as IBD and celiac disease. Lakartidningen. 2012; 109: 218-21.
 
[14]  Lomer MC, Parkes GC, Sanderson JD. Review article: lactose intolerance in clinical practice--myths and realities. Aliment Pharmacol Ther. 2008; 27: 93-103.
 
[15]  Heine RG, AlRefaee F, Bachina P, De Leon JC, Geng L, Gong S, et al. Lactose intolerance and gastrointestinal cow's milk allergy in infants and children - common misconceptions revisited. World Allergy Organ J. 2017; 10: 41.
 
[16]  Lerner A, Matthias T. The Salutogenic Effects of Cow’s Milk and Dairy Products in Celiac Disease. J of Clin & Cell Immunol 2018; 9; 2-7.
 
[17]  Agostoni C, Turck D. Is cow's milk harmful to a child's health? J Pediatr Gastroenterol Nutr. 2011; 53: 594-600.
 
[18]  Heyman MB; Committee on Nutrition. Lactose intolerance in infants, children, and adolescents. Pediatrics. 2006; 118: 1279-86.
 
[19]  Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A. Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence. Food Nutr Res. 2016; 60: 32527.
 
[20]  Marangoni F, Pellegrino L, Verduci E, Ghiselli A, Bernabei R, Calvani R, et al. Cow's Milk Consumption and Health: A Health Professional's Guide. J Am Coll Nutr. 2018 Sep 24: 1-12. [Epub ahead of print].
 
[21]  Donovan SM, Shamir R. Introduction to the yogurt in nutrition initiative and the First Global Summit on the health effects of yogurt. Am J Clin Nutr. 2014; 99: 1209S-11S.
 
[22]  Jankowiak C, Ludwig D. frequent causes of diarrhea: celiac disease and lactose intolerance. Med Klin (Munich). 2008; 103: 413-22; quiz 423-4.
 
[23]  Van Gossum M, Mascart F, Rickaert F, Codden T, Colonius V. Lactose and gluten intolerance: which to suscept. Rev Med Brux. 2000; 21: A303-8.
 
[24]  Spencer M, Lenhart A, Baker J, Dickens J, Weissman A, Read AJ, et al. Primary care physicians are under-testing for celiac disease in patients with iron deficiency anemia: Results of a national survey. PLoS One. 2017; 12: e0184754.
 
[25]  Waheed N, Cheema HA, Suleman H, Fayyaz Z, Mushtaq I, Muhammad, Hashmi A. Celiac Crisis: A Rare Or Rarely Recognized Disease. J Ayub Med Coll Abbottabad. 2016; 28: 672-675.
 
[26]  Prasad KK, Thapa BR, Nain CK, Sharma AK, Singh K. Brush border enzyme activities in relation to histological lesion in pediatric celiac disease. J Gastroenterol Hepatol. 2008; 23: e348-52.
 
[27]  Murphy MS, Sood M, Johnson T. Use of the lactose H2 breath test to monitor mucosal healing in coeliac disease. Acta Paediatr. 2002; 91: 141-4.
 
[28]  Ghoshal UC, Ghoshal U, Misra A, Choudhuri G. Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance. BMC Gastroenterol. 2004; 4: 10.
 
[29]  Leffler DA, Dennis M, Hyett B, Kelly E, Schuppan D, Kelly CP. Etiologies and predictors of diagnosis in nonresponsive celiac disease. Clin Gastroenterol Hepatol. 2007; 5: 445-50.
 
[30]  Ojetti V, Nucera G, Migneco A, Gabrielli M, Lauritano C, Danese S, et al. High prevalence of celiac disease in patients with lactose intolerance. Digestion. 2005; 71: 106-10.
 
[31]  Radlović N, Mladenović M, Leković Z, Ristić D, Pavlović M, Stojsić Z, et al. Lactose intolerance in infants with gluten-sensitive enteropathy: frequency and clinical characteristics. Srp Arh Celok Lek. 2009; 137: 33-7.
 
[32]  Barrett JS, Irving PM, Shepherd SJ, Muir JG, Gibson PR. Comparison of the prevalence of fructose and lactose malabsorption across chronic intestinal disorders. Aliment Pharmacol Ther. 2009; 30: 165-74.
 
[33]  Qiao R, Huang C, Du H, Zeng G, Li L, Ye S. Milk consumption and lactose intolerance in adults. Biomed Environ Sci. 2011; 24: 512-7.
 
[34]  Hyytinen M, Savilahti E, Virtanen SM, Härkönen T, Ilonen J, Luopajärvi K, et al. Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial. Gastroenterology. 2017; 153: 961-970. e3.
 
[35]  Dekking L, Koning F, Hosek D, Ondrak TD, Taylor SL, Schroeder JW, Bauer M. Intolerance of celiac disease patients to bovine milk is not due to the presence of T-cell stimulatory epitopes of gluten. Nutrition. 2009; 25: 122-3.
 
[36]  Cabrera-Chávez F, de la Barca AM. Bovine milk intolerance in celiac disease is related to IgA reactivity to alpha- and beta-caseins. Nutrition. 2009; 25: 715-6.
 
[37]  Hård Af Segerstad EM, Lee HS, Andrén Aronsson C, Yang J, Uusitalo U, Sjöholm I et al. Daily Intake of Milk Powder and Risk of Celiac Disease in Early Childhood: A Nested Case-Control Study. Nutrients. 2018 Apr 28; 10(5). pii: E550.