International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
Open Access
Journal Browser
International Journal of Celiac Disease. 2013, 1(1), 3-5
DOI: 10.12691/ijcd-1-1-2
Open AccessEditorial

Present View of the Management and Tasks in the Celiac Disease Field: From Diagnosis to Therapy

Peter Makovicky1, and Gabriel Samasca2

1Czech University of Life Sciences in Prague, Department of Veterinary Sciences, Prague, Czech Republic

2Iuliu Hatieganu University of Medicine and Pharmacy, Institution of Immunology, Cluj-Napoca, Romania

Pub. Date: November 27, 2013

Cite this paper:
Peter Makovicky and Gabriel Samasca. Present View of the Management and Tasks in the Celiac Disease Field: From Diagnosis to Therapy. International Journal of Celiac Disease. 2013; 1(1):3-5. doi: 10.12691/ijcd-1-1-2


Celiac disease is a disease where both children and adults are affected. It symptoms were previously described in Galen times. Today we recognize its starter, pathological mechanism, and also its atypical behaviour. There is only one causal therapeutic model in terms of compliance with the principles of lifelong strict gluten-free diet. It is an under-diagnosed disease. Further steps should be associated with the improvement of diagnosis and detection of all global forms of disease followed by proper care for patients, including prevention. The second part of the task is to support basic and applicable research with outcomes for further practice and therapeutic outcomes. It is an interdisciplinary issue with lack of its own publishing space. Given these facts, collaboration with the broader but highly professional Editorial Board found a new journal was: International Journal of Celiac Disease, which aims to address the issue at a high professional level, so the results could be applied in practice and science as well.

celiac disease diagnostics research

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Briani, C., Samaroo, D., Alaedini, A, Celiac disease: from gluten to autoimunity. Autoimmunity Reviews, 7 (8). 644-650. Sep.2008.
[2]  Catassi, C., Ratsch, I.M., Fabiani, E., Rossini, M., Bordicchia, F.,Candela, F., Coppa, G.V., Giorgi, P.L, Coeliac disease in the year 2000: exploring the iceberg. Lancet, 343 (8891). 200-203. Jan.1994.
[3]  Di Cagno, R., Barbato, M., Camillo, C., Rizzello, C.G., De Angelis, M., Giuliani, G., De Vincenzi, M., Gobbetti, M., Cucchiara, S, Gluten-free sourdough beat baked goods appeal safe for young celiac patiens: a pilot study. Journal of Pediatric Gastroenterology and Nutrition, 51 (6). 777-783. Dec.2010.
[4]  Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E.O., Schuppan, D, Identification of tissue transglutaminase as the autoantigen of celiac disease. Natural Medicine, 3 (7). 797-801. 1997.
[5]  Fasano, A., Catassi, C, Clinical practice. Celiac disease. New England Journal of Medicine, 367 (25). 2419-2426. Dec.2012.
[6]  Green, P.H., Jabri, B, Coeliac disease. Lancet, 362 (9381). 383-391. Aug.2003.
[7]  Husby, S., Koletzko, S., Korponay-Szabo, I.R., Mearin, M.L., Phillips, A., Shamir, R., Troncone, R., Giersiepen, K., Branski, D., Catassi, C., Lelgeman, M., Maki, M., Ribes-Konincki, C., Ventura, A., Zimmer, K.P; ESPGHAN Working Group on Celiac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition, European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. Journal of Pediatric Gastroenterology and Nutrition, 54 (1). 136-160. Jan.2012.
[8]  Chorzelski, T.P., Sulej, J., Tchorzewska, H., Jablonska, S., Beutner, E.H., Kumar, V, IgA class endomysium antibodies in dermatitis herpetiformis and coeliac disease. Annals of the New York Academy of Sciences, 420. 325-334. 1983.
[9]  Kollarova, H., Pektor, R., Smajstra, V., Dvorackova, J., Shonova, O., Janoutova, G., Janout, V, Routine duodenal biopsy conducted in the course of gastroskopy - posibility of asymptomatic celiac disease detection. Czech-Slovac Gastroenterology and Hepatology, 61 (5). 245-248. Oct.2007.
[10]  Marsh, M.N, Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity (‘celiac sprue’). Gastroenterology, 102 (1). 350-354.
[11]  Mubarak, A., Spierings, E., Wolters, V., van Hoogstraten, I., Kneepkens, C.M., Houwen, R, Human leukocyte antigen DQ2.2 and celiac disease. Journal of Pediatric Gastroenterology and Nutrition, 56 (4). 428-430. Apr.2013.
[12]  Mulder, C.J., Hadithi, M.M., Rostami, K., Goerres, M.S, Coeliac disease – has the time for routine mass screening? In 2002–2010–2020? Romanian Journal of Gastroenterology, 11 (3). 179-182. Sep.2002.
[13]  Oberhuber, G., Granditsch, G., Vogelsang, H, The histopathology of coeliac disease: time for a standardized report scheme for pathologists. European Journal of Gastroenterology & Hepatology, 11 (10). 1185-1194. Oct.1999.
[14]  Prince, H.E, Evaluation of the INOVA diagnostics enzyme-linked immunosorbent Sasy kiks for measuring serum imunoglobulin G (IgG) and IgA to deamidated gliadin peptides. Clinical and Vaccine Immunology, 13 (1). 150-151. Jan.2006.
[15]  Soresi, M., Pirrone, G., Giannitrapani, L., Lacono, G., Di Prima, L., La Spada, E., Di Fede, G., Ambrosiano, G., Montalto, G., Carroccio, A, A key role for abdominal ultrasound examination in “difficult” diagnoses of celiac disease. Ultraschall in der Medizin, 32 (S1). S52-S61. Jan.2011.