International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
Open Access
Journal Browser
International Journal of Celiac Disease. 2017, 5(4), 173-174
DOI: 10.12691/ijcd-5-4-10
Open AccessA Clinical Study

Ataxia Triggered by Gluten

Hakim Rahmoune1, 2, , Nada Boutrid1, 2, Mounira Amrane2, 3 and Belkacem Bioud1, 2

1Department of Pediatrics, University Hospital of Setif, Setif 1 University, Algeria

2Genetic, Cardiovascular & Nutritional Diseases Laboratory, Setif-1 University, Algeria

3Biochemistry Laboratory, University Hospital of Setif, Setif 1 University, Algeria

Pub. Date: November 24, 2017

Cite this paper:
Hakim Rahmoune, Nada Boutrid, Mounira Amrane and Belkacem Bioud. Ataxia Triggered by Gluten. International Journal of Celiac Disease. 2017; 5(4):173-174. doi: 10.12691/ijcd-5-4-10


The gluten ataxia is one of the commonest neurological manifestations of gluten-related disorders: prevalence was estimated at 15% amongst all ataxias and 40% of all idiopathic sporadic ataxias; its diagnosis should be confirmed by the prsence of anti-gliadin antibodies. Gluten ataxia is, by its management, very peculiar: few etiologies, among the large pannel of childhood ataxias, may respond to dietary treatments. We present an instructive case of gluten ataxia in a teenage girl.

ataxia gluten anti-gliadin antibodies diet

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Hadjivassiliou M, Sanders DS, Grünewald RA, Woodroofe N, Boscolo S, Aeschlimann D. Gluten sensitivity: from gut to brain. The Lancet Neurology. 2010 Mar 31; 9(3): 318-30.
[2]  Hadjivassiliou M, Boscolo S, Tongiorgi E, Grünewald RA, Sharrack B, Sanders DS, Woodroofe N, Davies‐Jones GA. Cerebellar ataxia as a possible organ‐specific autoimmune disease. Movement disorders. 2008. Jul 30; 23(10): 1370-7.
[3]  Jayadev S, Bird TD. Hereditary ataxias: overview. Genetics in Medicine. 2013. Mar 28; 15(9): 673-83.
[4]  Arnone JM, Conti RP. Neuropsychiatric features of celiac disease. International Journal of Celiac Disease. 2015. Sep 12; 3(3): 77-83.
[5]  Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PH, Hadjivassiliou M, Kaukinen K, Kelly CP, Leonard JN, Lundin KE. The Oslo definitions for coeliac disease and related terms. Gut. 2013. Jan 1; 62(1): 43-52.
[6]  Hadjivassiliou M, Sanders DD, Aeschlimann DP. Gluten-related disorders: gluten ataxia. Digestive Diseases. 2015; 33(2): 264-8.
[7]  Hadjivassiliou M, Sanders DS, Woodroofe N, Williamson C, Grünewald RA. Gluten ataxia. The Cerebellum. 2008. Sep 1; 7(3): 494-8.
[8]  Hadjivassiliou M, Aeschlimann P, Sanders DS, Mäki M, Kaukinen K, Grünewald RA, Bandmann O, Woodroofe N, Haddock G, Aeschlimann DP. Transglutaminase 6 antibodies in the diagnosis of gluten ataxia. Neurology. 2013. May 7; 80(19): 1740-5.
[9]  Mitoma H, Hadjivassiliou M, Honnorat J. Guidelines for treatment of immune-mediated cerebellar ataxias. Cerebellum & ataxias. 2015. Nov 10; 2(1): 14.
[10]  Hadjivassiliou M, Grünewald RA, Sanders DS, Shanmugarajah P, Hoggard N. Effect of gluten-free diet on cerebellar MR spectroscopy in gluten ataxia. Neurology. 2017. Aug 15; 89(7): 705-9.