International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: http://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2016, 4(2), 74-76
DOI: 10.12691/ijcd-4-2-8
Open AccessCase Report

Unusual Presentation of Celiac Disease in a Toddler from a Pediatric Surgery Unit

Laura Mihaela Trandafir1, Oana Teslariu1, Smaranda Diaconescu1, , Magda Iorga1, Ingrith Miron2, Ioan Sârbu3 and Iulia Carmen Ciongradi3

1Department of Pediatric, "Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania

2Department of Pharmacology, "Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania

3Department of Pediatric Surgery and Orthopedics,"Grigore T. Popa" University of Medicine and Pharmacy - Iasi, Romania

Pub. Date: May 28, 2016

Cite this paper:
Laura Mihaela Trandafir, Oana Teslariu, Smaranda Diaconescu, Magda Iorga, Ingrith Miron, Ioan Sârbu and Iulia Carmen Ciongradi. Unusual Presentation of Celiac Disease in a Toddler from a Pediatric Surgery Unit. International Journal of Celiac Disease. 2016; 4(2):74-76. doi: 10.12691/ijcd-4-2-8

Abstract

Celiac disease is an intestinal autoimmune disease induced by the ingestion of gluten proteins (wheat, rye, barley) in genetically susceptible individuals. Celiac disease can present with gastrointestinal or extraintestinal manifestations (malabsorbtion, diarrhea, constipation, liver, skin or bones disorders). We present the case of a 14-months-old girl admitted for altered general condition and symptoms of intestinal occlusion (severe abdominal pain, absence of feces, abdominal distension), with associated severe malnutrition. History revealed chronic diarrhea and a lactose intolerance diagnosed 3 months prior to admission. The biochemical and imaging investigations excluded any acute surgical pathology. The serological tests showed high values of anti-tissue transglutaminase antibodies. The intestinal biopsy confirmed celiac disease. In children with suspicion of intestinal obstruction associated with a history of diarrhea or constipation and failure to thrive, testing for celiac disease should be considered.

Keywords:
celiac disease children anti-tissue transglutaminase antibodies Pediatric Surgery Unit

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References:

[1]  Gujral N, Freeman HJ, Thomson ABR. Celiac disease: Prevalence, diagnosis, pathogenesis and treatment. World J Gastroenterol 2012; 18(42): 6036-6059.
 
[2]  Rampertab SD, Pooran N, Brar P, Singh P, Green PH. Trends in the presentation of celiac disease. Am J Med. 2006; 119(4):355.e9-14.
 
[3]  Telega G, Bennet TR, Werlin S. Emerging new clinical patterns in the presentation of celiac disease. Arch Pediatr Adolesc Med. 2008 Feb; 162(2):164-168.
 
[4]  Iacob D, Fufezan O, Farcau D et al. Celiac disease in toddler with atypical onset. Case report. Med Ultrason 2016; 18(1): 169-119.
 
[5]  Van der Windt DA, Jellema P, Mulder CJ et al. Diagnostic testing for celiac disease among patients with abdominal symptoms: a systematic review. JAMA 2010; 303: 1738-1746.
 
[6]  Di Sabatino A, Corazza GR. Celiac disease. Lancet 2009; 373(9673):1480-1493.
 
[7]  Schuppan D, Zimmer KP. The diagnosis and treatment of celiac disease. Dtsch Arztebl Int 2013; 110(49): 835-846.
 
[8]  Basaran Y, Simsek I, Gunal A. Celiac disease with a mixed pattern: a case report. Cases Journal 2009; 2:9330.
 
[9]  Anania C, De Luca E, De Castro G. Liver involvement in pediatric celiac disease. World J Gastroenterol 2015; 21(19): 5813-5822.
 
[10]  Lee GJ, Boyle B, Ediger T, Hill I. Hypertransaminasemia in newly diagnosed pediatric celiac disease patients. JPGN 2016.
 
[11]  Farre C, Esteve M, Curcoy A et al. Hypertransaminasemia in pediatric celiac disease patients and its prevalence as a diagnostic clue. Am J Gastroenterol. 2002; 97(12):3176-3181.
 
[12]  Reilly NR, Aguilar KM, Green PH. Should intussusception in children prompt screening for celiac disease? J Pediatr Gastroenterol Nutr. 2013 Jan; 56(1):56-59.
 
[13]  Hizal G, Gürakan F, Balamtekın N, Uslu Kizilkan N. Celiac disease presenting with intestinal obstruction: report of two cases. Turk J Gastroenterol. 2012 Aug; 23(4):416-417.
 
[14]  Gonda TA, Khan SU, Cheng J, Lewis SK, Rubin M, Green PH. Association of intussusception and celiac disease in adults. Dig Dis Sci. 2010 Oct; 55(10):2899-2903.
 
[15]  Ludvigsson JF, Nordenskjöld A, Murray JA, Olén O. A large nationwide population-based case-control study of the association between intussusception and later celiac disease. BMC Gastroenterol. 2013 May 16; 13:89.
 
[16]  Garnier-Lengliné H, Cerf-Bensussan N, Ruemmele FM3. Celiac disease in children. Clin Res Hepatol Gastroenterol. 2015; 39(5):544-551.