International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2016, 4(2), 71-73
DOI: 10.12691/ijcd-4-2-9
Open AccessCase Report

Nonspecific Symptoms in Celiac Disease- Case Report

Valentina Sas1, Camelia I. Bud2, , Ioana Fodor2 and Sorin C. Man1

1Mother and Child Department, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania

2Third Pediatric Clinic, Emergency Clinical Hospital for Children, Cluj-Napoca, Romania

Pub. Date: May 28, 2016

Cite this paper:
Valentina Sas, Camelia I. Bud, Ioana Fodor and Sorin C. Man. Nonspecific Symptoms in Celiac Disease- Case Report. International Journal of Celiac Disease. 2016; 4(2):71-73. doi: 10.12691/ijcd-4-2-9


Celiac disease is an immune-mediated systemic disorder with a genetic predisposition. The availability of more specific serology tests showed that celiac disease is more common than previously suspected and that many patients do not demonstrate specific clinical or even histological sings. We present a case of celiac disease with the unset at 5 years, with recurrent episodes of diarrhea, weight loss and anemia. The serology tests showed a high level of IgA tissue transglutaminase antibodies, exceeding 10 times the upper limit but the intestinal biopsy showed normal size villi, intact surface epithelium and a lymphoplasmacytic infiltrate at chorionic level (Marsh 1). The diagnosis of celiac disease was confirmed by resolution of symptoms and normal tissue transglutaminase antibodies level, six month after starting the gluten free diet.

celiac disease children diagnosis challenge

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