International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2016, 4(1), 7-8
DOI: 10.12691/ijcd-4-1-2
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Counting Intraepithelial Lymphocytes. Immunohistochemistry and Flow Cytometer are Necessary New Steps in the Diagnosis of Celiac Disease

Amado Salvador Peña1,

1Department of Microbiology & Infection Control, Laboratory of Immunogenetics, VU University Medical Center, HZ Amsterdam, The Netherlands

Pub. Date: February 16, 2016

Cite this paper:
Amado Salvador Peña. Counting Intraepithelial Lymphocytes. Immunohistochemistry and Flow Cytometer are Necessary New Steps in the Diagnosis of Celiac Disease. International Journal of Celiac Disease. 2016; 4(1):7-8. doi: 10.12691/ijcd-4-1-2


The simple quantitation of intraepithelial lymphocytes per 100 epithelial cells in small bowel has been a valuable addition to the study of the histopathology of celiac disease. However new technology is necessary to increase the accuracy and significance of the subtypes of intraepithelial lymphocytes in the differential diagnosis and the evaluation of gluten related disorders.

celiac disease intraepithelial lymphocytes enterocytes small bowel

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