Is screening for Celiac Disease Needed in Patients with Liver Disease?

Janaína Luz Narciso-Schiavon; Leonardo L. Schiavon

International Journal of Celiac Disease. 2015, 3(3), 91-94
DOI: 10.12691/ijcd-3-3-2

Open AccessArticle

Is screening for Celiac Disease Needed in Patients with Liver Disease?

Janaína Luz Narciso-Schiavon^1, and Leonardo L. Schiavon¹

¹Department of Internal Medicine, Division of Gastroenterology, Federal University of Santa Catarina, Santa Catarina, Brazil

Pub. Date: June 24, 2015

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Cite this paper:
Janaína Luz Narciso-Schiavon and Leonardo L. Schiavon. Is screening for Celiac Disease Needed in Patients with Liver Disease?. International Journal of Celiac Disease. 2015; 3(3):91-94. doi: 10.12691/ijcd-3-3-2

Abstract

Celiac disease is known for its classic clinical manifestations such as anemia and diarrhea. Liver involvement in celiac disease has been studied for more than thirty years. We review different etiologies of liver diseases and their possible association with celiac disease and seek to define in which situations serological screening should be performed.

Keywords:
celiac disease liver diseases liver cirrhosis alanine transaminase autoimmune hepatitis

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References:

[1]	Freeman HJ. Celiac disease: a disorder emerging from antiquity, its evolving classification and risk, and potential new treatment paradigms. Gut and liver 2015; 9(1): 28-37.

[2]	Walker MM, Murray JA. An update in the diagnosis of coeliac disease. Histopathology 2011; 59(2): 166-179.

[3]	Wakim-Fleming J, Pagadala MR, McCullough AJ, Lopez R, Bennett AE, Barnes DS, Carey WD. Prevalence of celiac disease in cirrhosis and outcome of cirrhosis on a gluten free diet: a prospective study. Journal of hepatology 2014; 61(3): 558-563.

[4]	Carroccio A, Soresi M, Di Prima L, Montalto G. Screening for celiac disease in patients with chronic liver disease. Gastroenterology 2003; 125(4): 1289; author reply 1289-1290.

[5]	Green PH, Jabri B. Coeliac disease. Lancet 2003; 362(9381): 383-391.

[6]	Hadjivassiliou M, Sanders DS, Grunewald RA, Woodroofe N, Boscolo S, Aeschlimann D. Gluten sensitivity: from gut to brain. The Lancet Neurology 2010; 9(3): 318-330.

[7]	Hall NJ, Rubin G, Charnock A. Systematic review: adherence to a gluten-free diet in adult patients with coeliac disease. Alimentary pharmacology & therapeutics 2009; 30(4): 315-330.

[8]	Bardella MT, Fraquelli M, Quatrini M, Molteni N, Bianchi P, Conte D. Prevalence of hypertransaminasemia in adult celiac patients and effect of gluten-free diet. Hepatology (Baltimore, Md) 1995; 22(3): 833-836.

[9]	Lindberg J, Ahren C, Jonsson J. Gluten-free diet in chronic active hepatitis associated with intestinal villous atrophy. Hepato-gastroenterology 1982; 29(2): 52-54.

[10]	J.L. N-S, L.L. S. Should Patients with Liver Disease be Screened for Celiac Disease? J Res Development 2014; 116(2).

[11]	Drastich P, Honsova E, Lodererova A, Jaresova M, Pekarikova A, Hoffmanova I, Tuckova L, Tlaskalova-Hogenova H, Spicak J, Sanchez D. Celiac disease markers in patients with liver diseases: a single center large scale screening study. World journal of gastroenterology : WJG 2012; 18(43): 6255-6262.

[12]	Sainsbury A, Sanders DS, Ford AC. Meta-analysis: Coeliac disease and hypertransaminasaemia. Alimentary pharmacology & therapeutics 2011; 34(1): 33-40.

[13]	Vajro P, Paolella G, Pisano P, Maggiore G. Hypertransaminasemia and coeliac disease. Alimentary pharmacology & therapeutics 2012; 35(1): 202-203; author reply 203-204.

[14]	Duggan JM, Duggan AE. Systematic review: the liver in coeliac disease. Alimentary pharmacology & therapeutics 2005; 21(5): 515-518.

[15]	Rodrigo L. Celiac disease. World journal of gastroenterology : WJG 2006; 12(41): 6585-6593.

[16]	van Gerven NM, Bakker SF, de Boer YS, Witte BI, Bontkes H, van Nieuwkerk CM, Mulder CJ, Bouma G. Seroprevalence of celiac disease in patients with autoimmune hepatitis. European journal of gastroenterology & hepatology 2014; 26(10): 1104-1107.

[17]	Di Biase AR, Colecchia A, Scaioli E, Berri R, Viola L, Vestito A, Balli F, Festi D. Autoimmune liver diseases in a paediatric population with coeliac disease - a 10-year single-centre experience. Alimentary pharmacology & therapeutics 2010; 31(2): 253-260.

[18]	Logan RF, Ferguson A, Finlayson ND, Weir DG. Primary biliary cirrhosis and coeliac disease: an association? Lancet 1978; 1(8058): 230-233.

[19]	Habior A, Lewartowska A, Orlowska J, Zych W, Sankowska M, Bauer A, Butruk E. Association of coeliac disease with primary biliary cirrhosis in Poland. European journal of gastroenterology & hepatology 2003; 15(2): 159-164.

[20]	Gillett HR, Cauch-Dudek K, Jenny E, Heathcote EJ, Freeman HJ. Prevalence of IgA antibodies to endomysium and tissue transglutaminase in primary biliary cirrhosis. Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000; 14(8): 672-675.

[21]	Chatzicostas C, Roussomoustakaki M, Drygiannakis D, Niniraki M, Tzardi M, Koulentaki M, Dimoulios P, Mouzas I, Kouroumalis E. Primary biliary cirrhosis and autoimmune cholangitis are not associated with coeliac disease in Crete. BMC gastroenterology 2002; 2: 5.

[22]	Al-Osaimi AM, Berg CL. Association of primary sclerosing cholangitis and celiac disease: a case report and review of the literature. Digestive diseases and sciences 2004; 49(3): 438-443.

[23]	Gillberg R, Dotevall G, Ahren C. Chronic inflammatory bowel disease in patients with coeliac disease. Scandinavian journal of gastroenterology 1982; 17(4): 491-496.

[24]	Bardella MT, Valenti L, Pagliari C, Peracchi M, Fare M, Fracanzani AL, Fargion S. Searching for coeliac disease in patients with non-alcoholic fatty liver disease. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2004; 36(5): 333-336.

[25]	Grieco A, Miele L, Pignatoro G, Pompili M, Rapaccini GL, Gasbarrini G. Is coeliac disease a confounding factor in the diagnosis of NASH? Gut 2001; 49(4): 596.

[26]	Rahimi AR, Daryani NE, Ghofrani H, Taher M, Pashaei MR, Abdollahzade S, Kalani M, Ajdarkosh H. The prevalence of celiac disease among patients with non-alcoholic fatty liver disease in Iran. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2011; 22(3): 300-304.

[27]	Abenavoli L, Luigiano C, Larussa T, Milic N, De Lorenzo A, Stelitano L, Morace C, Consolo P, Miraglia S, Fagoonee S, Virgilio C, Luzza F, Pellicano R. Liver steatosis in celiac disease: the open door. Minerva gastroenterologica e dietologica 2013; 59(1): 89-95.

[28]	Abenavoli L, Milic N, De Lorenzo A, Luzza F. A pathogenetic link between non-alcoholic fatty liver disease and celiac disease. Endocrine 2013; 43(1): 65-67.

[29]	Nau AL, Fayad L, Lazzarotto C, Shiozawa MB, Dantas-Correa EB, Schiavon Lde L, Narciso-Schiavon JL. Prevalence and clinical features of celiac disease in patients with hepatitis B virus infection in Southern Brazil. Revista da Sociedade Brasileira de Medicina Tropical 2013; 46(4): 397-402.

[30]	Leonardi S, La Rosa M. Are hepatitis B virus and celiac disease linked? Hepatitis monthly 2010; 10(3): 173-175.

[31]	Ertekin V, Tosun MS, Selimoglu MA. Is there need for a new hepatitis B vaccine schedule for children with celiac disease? Hepatitis monthly 2011; 11(8): 634-637.

[32]	Rostami Nejad M, Rostami K, Zali MR. Hepatitis B vaccination reliability in celiac disease. Hepatitis monthly 2011; 11(8): 597-598.

[33]	Fine KD, Ogunji F, Saloum Y, Beharry S, Crippin J, Weinstein J. Celiac sprue: another autoimmune syndrome associated with hepatitis C. The American journal of gastroenterology 2001; 96(1): 138-145.

[34]	Durante-Mangoni E, Iardino P, Resse M, Cesaro G, Sica A, Farzati B, Ruggiero G, Adinolfi LE. Silent celiac disease in chronic hepatitis C: impact of interferon treatment on the disease onset and clinical outcome. Journal of clinical gastroenterology 2004; 38(10): 901-905.

[35]	Thevenot T, Denis J, Jouannaud V, Monnet E, Renou C, Labadie H, Abdelli N, Nguyen-Khac E, Dumouchel P, Bresson-Hadni S, Chousterman M, V DIM, Cadranel JF. Coeliac disease in chronic hepatitis C: a French multicentre prospective study. Alimentary pharmacology & therapeutics 2007; 26(9): 1209-1216.

[36]	Narciso-Schiavon JL, L. SL. Autoantibodies in Chronic Hepatitis C: a Clinical Perspective. World Journal of Hepatology 2015; 7(5): 1074-1085.

[37]	Ghany MG, Nelson DR, Strader DB, Thomas DL, Seeff LB. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology (Baltimore, Md) 2011; 54(4): 1433-1444.

[38]	Adinolfi LE, Durante Mangoni E, Andreana A. Interferon and ribavirin treatment for chronic hepatitis C may activate celiac disease. The American journal of gastroenterology 2001; 96(2): 607-608.

[39]	Zamani F, Amiri A, Shakeri R, Zare A, Mohamadnejad M. Celiac disease as a potential cause of idiopathic portal hypertension: a case report. Journal of medical case reports 2009; 3: 68.

[40]	Sharma BC, Bhasin DK, Nada R. Association of celiac disease with non-cirrhotic portal fibrosis. Journal of gastroenterology and hepatology 2006; 21(1 Pt 2): 332-334.

[41]	Maiwall R, Goel A, Pulimood AB, Babji S, Sophia J, Prasad C, Balasubramanian KA, Ramakrishna B, Kurian S, Fletcher GJ, Abraham P, Kang G, Ramakrishna BS, Elias E, Eapen CE. Investigation into celiac disease in Indian patients with portal hypertension. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2014; 33(6): 517-523.

[42]	Eapen CE, Nightingale P, Hubscher SG, Lane PJ, Plant T, Velissaris D, Elias E. Non-cirrhotic intrahepatic portal hypertension: associated gut diseases and prognostic factors. Digestive diseases and sciences 2011; 56(1): 227-235.

[43]	Ratziu V, Nourani M, Poynard T. Discussion on celiac disease in patients with severe liver disease: gluten-free diet may reverse hepatic failure. Gastroenterology 2002; 123(6): 2158-2159; author reply 2159-2160.

[44]	Kaukinen K, Halme L, Collin P, Farkkila M, Maki M, Vehmanen P, Partanen J, Hockerstedt K. Celiac disease in patients with severe liver disease: gluten-free diet may reverse hepatic failure. Gastroenterology 2002; 122(4): 881-888.

[45]	Al-Hussaini A, Basheer A, Czaja AJ. Liver failure unmasks celiac disease in a child. Annals of hepatology 2013; 12(3): 501-505.

[46]	Roumeliotis N, Hosking M, Guttman O. Celiac disease and cardiomyopathy in an adolescent with occult cirrhosis. Paediatrics & child health 2012; 17(8): 437-439.