International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2015, 3(2), 69-71
DOI: 10.12691/ijcd-3-2-4
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Neuropsychiatric Manifestations of Celiac Disease in Young Child – Case Report

Mircea Margescu1, 2, , Camelia Carmen Margescu1, Rodica Elena Pantis3, MadalinaIonela Chiriac4 and Rodica Cornean1, 2

1II- nd Pediatric Department of Clinical Pediatrics Emergency Hospital Cluj-Napoca, Romania

2Phd “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

3Pediatric Psychiatry Department of Clinical Pediatrics Emergency Hospital Cluj-Napoca, Romania

4Pediatric Surgery Department of Clinical Pediatrics Emergency Hospital Cluj-Napoca, Romania

Pub. Date: May 04, 2015

Cite this paper:
Mircea Margescu, Camelia Carmen Margescu, Rodica Elena Pantis, MadalinaIonela Chiriac and Rodica Cornean. Neuropsychiatric Manifestations of Celiac Disease in Young Child – Case Report. International Journal of Celiac Disease. 2015; 3(2):69-71. doi: 10.12691/ijcd-3-2-4


Neurological and psychiatric symptoms represent an atypical manifestation of celiac disease (CD) occurring before the typical gastrointestinal events (weight loss, diarrhea, steatorrhoeic stools). Some studies suggest that a gluten-free diet is effective in treating psychiatric and neurological complications associated with CD. We report the case of 1 year and 10 months female child presented in II-nd Pediatrics Clinic of Clinical Pediatrics Emergency Hospital Cluj-Napoca with important neuropsychiatric manifestations (psychomotor tension, sobbing spasms, affective lability, separation anxiety and social anxiety, non-organic disorders sleeping) and typical manifestations of CD (loss of appetite, weight loss). The family history (paternal grandfather diagnose with intestinal lymphoma, mother suffering of type I diabetes and autoimmune thyroiditis - AT) relive the association with other autoimmune diseases and possible complications of CD. Complete remission of all clinical manifestations under the gluten confirms that symptoms were in the context of CD.

neuro-psychiatric manifestations child celiac disease autoimmunity

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