International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
Open Access
Journal Browser
International Journal of Celiac Disease. 2014, 2(1), 27-30
DOI: 10.12691/ijcd-2-1-8
Open AccessEditorial

Spiral Enteroscopy Value for the Celiac Disease Diagnosis and Management

Ofelia Mosteanu1, 2, Teodora Atena Pop1, 2, , Adina Hadade1, 3 and Marcel Tantau1, 2

1“Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Romania

2Department of Gastroenterology, Regional Institute of Gastroenterology and Hepatology “Prof.Dr.O.Fodor” Cluj-Napoca, Romania

3Department of Anesthesiology, Regional Institute of Gastroenterology and Hepatology “Prof.Dr.O.Fodor” Cluj-Napoca, Romania

Pub. Date: February 21, 2014

Cite this paper:
Ofelia Mosteanu, Teodora Atena Pop, Adina Hadade and Marcel Tantau. Spiral Enteroscopy Value for the Celiac Disease Diagnosis and Management. International Journal of Celiac Disease. 2014; 2(1):27-30. doi: 10.12691/ijcd-2-1-8


Recently, spiral enteroscopy (SE) has been promoted as an alternative technique to obtain deep access into the small bowel. Using this technique, one may assess the distal small bowel mucosal alterations or monitor the developing of complications in celiac disease (CD) patients. Thus, SE value derives from the possibility of tissue sampling and consequently, modifying further the patient’s management. Spiral enteroscopy should be reserved for patients who are developing complications during celiac disease follow-up. It is not advisable to perform enteroscopy as the initial work-up of suspected CD patients.

spiral enteroscopy celiac disease enteropathy associated T-cell lymphoma

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Corazza, G., Villanacci, V., “Coeliac disease”, J Clin Pathol,. 58(6). 573-574. Jun 2005.
[2]  Marsh, N.M., “Another Milestone Passed”, International Journal of Celiac Disease, 1(1). 1-2. 2013.
[3]  Ravelli, A., Bolognini, S., Gambarotti, M., Villanacci, V., “Variability of histologic lesions in relation to biopsy site in gluten-sensitive enteropathy”, Am J Gastroenterol, 100(1), 177-185, Jan 2005.
[4]  Rondonotti, E., Spada, C., Cave, D., Pennazio, M., Riccioni, M.E., De Vitis, I., Schneider, D., Sprujevnik, T., Villa, F., Langelier, J., Arrigoni, A., Costamagna, G., de Franchis, R., “Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study”, Am J Gastroenterol, 102(8): 1624-1631, Aug 2007.
[5]  Akerman, P.A., Agrawal, D., Cantero, D., Pangtay, J., “Spiral enteroscopy with the new DSB overtube: a novel technique for deep peroral small-bowel intubation”, Endoscopy, 40(12), 974-978, Dec 2008.
[6]  Tomba, C., Elli, L., Bardella, M.T., Soncini, M., Contiero, P., Roncoroni, L., Locatelli, M., Conte, D., « Enteroscopy for the early detection of small bowel tumours in at-risk celiac patients”, Dig Liver Dis, in press, Jan 2014.
[7]  Van Weyenberg, S. J. B., S.V.A. Jarbandhan, S.V.A., Mulder, C.J.J., Jacobs, M.A.J.M., “Double Balloon Endoscopy in Celiac Disease”, Techniques in Gastrointestinal Endoscopy, 10(2), 87-93; Apr 2008.
[8]  Kurien, M., Evans, K.E., Aziz, I., Sidhu, R., Drew, K., Rogers, T.L., McAlindon, M.E., Sanders, D.S., “Capsule endoscopy in adult celiac disease: a potential role in equivocal cases of celiac disease?”, Gastrointest Endosc, 77(2), 227-232, Feb 2013.
[9]  Kav, T., Sivri, B., “Is enteroscopy necessary for diagnosis of celiac disease?”, World J Gastroenterol, 18(31), 4095-4101, Aug 2012.
[10]  Tomba C, Branchi F, Conte D, Bardella M.T., Elli L., “Role of Enteroscopic Techniques in Malignant Complications of Celiac Disease”, International Journal of Celiac Disease, 2(1), 1-3, Jan 2014.
[11]  Daveson, A.J., Anderson, R.P., “Small bowel endoscopy and coeliac disease”, Best Pract Res Clin Gastroenterol, 26(3), 315-323, Jun 2012.
[12]  Ashton-Key, M., Diss, T.C., Pan, L., Du, M.Q., Isaacson, P.G., “Molecular analysis of T-cell clonality in ulcerative jejunitis and enteropathy-associated T-cell lymphoma”, Am J Pathol, 151(2), 493-498, Aug 1997.
[13]  Soria, F., Lopez-Albors, O., Morcillo, E., Sarria, R., Carballo, F., Perez-Cuadrado, E., Sanchez, F., Latorre, R., “Experimental laparoscopic evaluation of double balloon versus spiral enteroscopy in an animal model”, Dig. Endosc, 23(1), 98, Jan 2011.
[14]  Morgan, D., Upchurch, B., Draganov, P’., Binmoeller, K.F., Haluszka, O., Jonnalagadda, S., Okolo, P., Grimm, I., Judah, J., Tokar, J., Chiorean, M., “Spiral enteroscopy: prospective US multicenter study in patients with small-bowel disorders”, Gastrointest. Endosc, 72(5), 992-998, Nov 2010.
[15]  Yamada, A., Watabe, H., Oka, S., Kogure, H., Imagawa, H., Kobayashi, Y., Suzuki, H., Watari, I., Aoyama, T., Isayama, H., Yamaji, Y., Fujishiro, M., Tanaka, S., Koike, K., “Feasibility of spiral enteroscopy in Japanese patients: study in two tertiary hospitals”, Dig Endosc, 25(4), 406-411, Jul 2013.
[16]  Akerman, P.A., Cantero, D., “Severe complications of spiral enteroscopy in the first 1750 patients”, Gastrointest Endosc, 69, AB127, 2009.