Towards Finding More Diagnostic Serological Markers in Celiac Disease: Can Deamidated Gliadin Peptide Antibodies Help to Our Babies?

Nur Arslan^1,

¹Dokuz Eylul University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Izmir, TURKEY

Cite this paper:
Nur Arslan. Towards Finding More Diagnostic Serological Markers in Celiac Disease: Can Deamidated Gliadin Peptide Antibodies Help to Our Babies?. International Journal of Celiac Disease. 2013; 1(1):27-28. doi: 10.12691/ijcd-1-1-10

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]	Dubé C, Rostom A, Sy R, Cranney A, Saloojee N, Garritty C, Sampson M, Zhang L, Yazdi F, Mamaladze V, Pan I, Macneil J, Mack D, Patel D, Moher D. The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 2005; 128(4 Suppl 1):S57-67.
[2]	Giersiepen K, Lelgemann M, Stuhldreher N, Ronfani L, Husby S, Koletzko S, Korponay-Szabó IR; ESPGHAN Working Group on Coeliac Disease Diagnosis. Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report. J Pediatr Gastroenterol Nutr 2012; 54:229-241.
[3]	Hill PG, Holmes GK. Coeliac disease: a biopsy is not always necessary for diagnosis. Aliment Pharmacol Ther 2008; 27:572-577.
[4]	Lefter DA, Schuppan D. Update on serologic testing in celiac disease. Am J Gastroenterol 2010; 105:2520-2524.
[5]	Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, Troncone R, Giersiepen K, Branski D, Catassi C, Lelgeman M, Mäki M, Ribes-Koninckx C, Ventura A, Zimmer KP; ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012; 54:136-160.
[6]	Margaritte-Jeannin P, Babron MC, Bourgey M, Louka AS, Clot F, Percopo S, Coto I, Hugot JP, Ascher H, Sollid LM, Greco L, Clerget-Darpoux F. HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease. Tissue Antigens 2004; 63:562-567.
[7]	Prause C, Ritter M, Probst C, Daehnrich C, Schlumberger W, Komorowski L, Lieske R, Richter T, Hauer AC, Stern M, Uhlig HH, Laass MW, Zimmer KP, Mothes T. Antibodies against deamidated gliadin as new and accurate biomarkers of childhood coeliac disease. J Pediatr Gastroenterol Nutr 2009; 49:52-58.
[8]	Hope BC, Ameratunga R, Austin PM, Evans HM, MacFarlane J, Mouat S, Chin SE. Diagnostic utility of modified gliadin peptide antibody assays in New Zealand children. J Pediatr Gastroenterol Nutr 2013; 57:43-48.
[9]	Amarri S, Alvisi P, De Giorgio R, Gelli MC, Cicola R, Tovoli F, Sassatelli R, Caio G, Volta U. Antibodies to deamidated gliadin peptides: an accurate predictor of coeliac disease in infancy. J Clin Immunol 2013; 33:1027-1030.
[10]	Blesa-Baviera LC, Donat Aliaga E, Ortigosa L, Litwin N, Peña-Quintana L, Méndez V, González MV, López-Manzanares JM, Méndez E, Koninckx CR. Celiac disease screening by immunochromatographic visual assays: results of a multicenter study. J Pediatr Gastroenterol Nutr 2007; 45:546-550.
[11]	Olen O, Gudjónsdóttir AH, Browaldh L, Hessami M, Elvin K, Liedberg AS, Neovius M, Grahnquist L. Antibodies against deamidated gliadin peptides and tissue transglutaminase for diagnosis of pediatric celiac disease. J Pediatr Gastroenterol Nutr 2012; 55:695-700.
[12]	Oana B, Otilia M. The usefulness of IgA/IgG DGP/tTG screen assay for celiac disease detection among symptomatic and at risk young children. Int J Celiac Dis 2013; 1:23-26.