International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: http://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2020, 8(1), 22-27
DOI: 10.12691/ijcd-8-1-4
Open AccessReview Article

Celiac Disease and Its Clinical Manifestations

Poornima Sharma1, Shaik Khasimbi2 and Sharad Wakode2,

1Department of Quality Assurance, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, India

2Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, India

Pub. Date: April 27, 2020

Cite this paper:
Poornima Sharma, Shaik Khasimbi and Sharad Wakode. Celiac Disease and Its Clinical Manifestations. International Journal of Celiac Disease. 2020; 8(1):22-27. doi: 10.12691/ijcd-8-1-4

Abstract

Celiac disease (CD) is associated with activation of the immune response toward specific protein commonly known as gluten, Which causes damage to the small finger-like projections called villi. Samuel was the first person who describes the disease in the year 1887. The given review article describes various factors which are associated with CD such as genetic factors, environmental factors and proteins. Chronic diarrhea, Hypochromic anemia, Short stature, Bone loss, Recurrent abortions, Hashimoto’s disease, etc are some common clinical manifestation. Along with clinical manifestations, we will also discuss the diet for the patients and treatment approaches.

Keywords:
celiac disease autoimmune disorder small intestine gluten villi

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