International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: http://www.sciepub.com/journal/ijcd Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2019, 7(2), 53-55
DOI: 10.12691/ijcd-7-2-5
Open AccessArticle

Sprue-Like Intestinal Disease Complicated by Inclusion Body Myositis

Hugh J. Freeman1,

1Department of Medicine (Gastoenterology), University of British Columbia, Vancouver, British Columbia, Canada

Pub. Date: August 13, 2019

Cite this paper:
Hugh J. Freeman. Sprue-Like Intestinal Disease Complicated by Inclusion Body Myositis. International Journal of Celiac Disease. 2019; 7(2):53-55. doi: 10.12691/ijcd-7-2-5

Abstract

A woman with long-standing weight loss and malabsorption demonstrated a severe sprue-like enteropathy. She insidiously developed persistent and progressive muscle weakness caused by inclusion body myositis, an uncommon muscle disorder. Treatment with a gluten-free diet, steroids, calcium, zinc and vitamin supplements, including empirical vitamin E resulted in weight gain, but failed to histologically improve her small intestinal mucosa or the muscle weakness which became profound. The myopathic process could reflect a co-existent autoimmune disorder, or, possibly a direct result of long-standing and superimposed nutrient deficits. An alternative explanation may be a hitherto unrecognized syndrome manifested as inclusion body myositis and a form of sprue-like enteropathy.

Keywords:
celiac disease gluten enteropathy small bowel ulcer non-granulomatous ulcerative jejunitis myopathy inclusion body myositis

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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