International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2019, 7(2), 48-52
DOI: 10.12691/ijcd-7-2-7
Open AccessArticle

The Facts of Celiac Disease; A Comprehensive Review

Nastaran Asri1 and Mohammad Rostami-Nejad2,

1Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Pub. Date: August 13, 2019

Cite this paper:
Nastaran Asri and Mohammad Rostami-Nejad. The Facts of Celiac Disease; A Comprehensive Review. International Journal of Celiac Disease. 2019; 7(2):48-52. doi: 10.12691/ijcd-7-2-7


Celiac disease (CD) is the most common permanent T-cell mediated gluten intolerance, caused by the dietary gluten in individuals who are genetically susceptible to the disease. CD characterized by small intestine mucosal lesions, subtotal, or total intestinal villi atrophy and nutrient malabsorptions. Sometimes the diagnosis of CD is so challenging and needs a combination of clinical, serological, histopathological and genetic evaluations. The well-known cornerstone treatment of CD is gluten-free diet (GFD) and there is need to regular monitoring of patients after starting the GFD. The main aim of this review was to discussing the definition and pathogenesis of CD, together with the diagnostics, treatment and follow-up strategies in this disease.

celiac disease glutens t-lymphocytes diet gluten-free diagnosis

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