International Journal of Celiac Disease
ISSN (Print): 2334-3427 ISSN (Online): 2334-3486 Website: Editor-in-chief: Samasca Gabriel
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International Journal of Celiac Disease. 2019, 7(1), 31-32
DOI: 10.12691/ijcd-7-1-6
Open AccessArticle

The Link between the Clinical Features of Atopic Dermatitis and Gluten-related Disorders

Mara Sur1, Andreea Aldea2, Loredana Dascal3, Emanuela Duca4, Ciprian Silaghi5, Lucia Sur6, and Cornel Aldea3, 7

1Municipal Hospital - Turda, Romania

2Medical Student, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

3Emergency Hospital for Children, Cluj-Napoca, Romania

4Emanuela Duca, Regional Institute of Gastroenterology-Hepatology Prof. Dr.Octavian Fodor, Cluj-Napoca, Romania

5Department of Biochemistry, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

6Department of Pediatrics I, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

7Department of Pediatrics II, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

Pub. Date: March 27, 2019

Cite this paper:
Mara Sur, Andreea Aldea, Loredana Dascal, Emanuela Duca, Ciprian Silaghi, Lucia Sur and Cornel Aldea. The Link between the Clinical Features of Atopic Dermatitis and Gluten-related Disorders. International Journal of Celiac Disease. 2019; 7(1):31-32. doi: 10.12691/ijcd-7-1-6


Patients affected by non-celiac gluten sensitivity usually report both intestinal and extra-intestinal symptoms arising shortly after the ingestion of gluten-containing food. Atopic dermatitis is a chronic inflammatory skin disease that affects both children and adults. We present the case of a family composed of a mother (32 years old) and her two daughters (6 and 9 years old) who were diagnosed with atopic dermatitis and gluten related disorders.

atopic dermatitis gluten-related disorders gluten free diet

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[1]  Guttman-Yassky E, Hanifin JM, Boguniewicz M, Wollenberg A, Bissonnette R, Purohit V, Kilty I, Tallman AM, Zielinski MA. The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition. Exp Dermatol 2018; 28: 3-10.
[2]  Milam EC, Jacob SE, Cohen DE. Contact Dermatitis in the Patient with Atopic Dermatitis. J Allergy Clin Immunol Pract 2019; 7: 18-26.
[3]  Paller AS, Spergel JM, Mina-Osorio P, Irvine AD. The atopic march and atopic multimorbidity: Many trajectories, many pathways. J Allergy Clin Immunol 2019; 143: 46-55.
[4]  Aldea CO, Sur D, Silaghi C. Hypercoagulability State in Celiac Disease and Hepatitis C Association. International Journal of Celiac Disease 2018; 6(3): 74-75.
[5]  Samasca G, Ramesh A, Sur D, Aldea CO, Sur L, Floca E, Sur G, Lupan I, Matthias T, Lerner A. Polyautoimmunity - The missing ingredient. Autoimmunity Reviews 17(8): 840-841.
[6]  Elli L, Branchi F, Tomba C, Villalta D, Norsa L, Ferretti F, Roncoroni L1, Bardella MT1. Diagnosis of gluten related disorders: Celiac disease, wheat allergy and non-celiac gluten sensitivity. World J Gastroenterol 2015; 21: 7110-7109.
[7]  Sur G. Clinical Presentation of Celiac Disease Masks Therapeutic Perspectives of Celiac Disease. Pharm Anal Acta 2013; 4: 1-3.
[8]  Gibiino G, Lopetuso L, Ricci R, Gasbarrini A, Cammarota G. Coeliac disease under a microscope: Histological diagnostic features and confounding factors. Comput Biol Med 2019; 104: 335-338.
[9]  Christensen MJ, Stahl Skov P, Poulsen LK, Bindslev-Jensen C, Mortz CG. Clinical relevance of sensitization to hydrolyzed wheat protein in wheat-sensitized subjects. J Allergy Clin Immunol 2018; 141: 802-805.
[10]  Barbaro MR, Cremon C, Stanghellini V, Barbara G. Recent advances in understanding non-celiac gluten sensitivity. F1000Research 2018; 7: 1631.
[11]  Potter MDE, Walker MM, Keely S, Talley NJ. What’s in a name? “Non-coeliac gluten or wheat sensitivity”: controversies and mechanisms related to wheat and gluten causing gastrointestinal symptoms or disease. Gut 2018; 67: 2073-2077.
[12]  Miclea DL, Al Khzouz C, Bucerzan S, Creț V, Lazea C, Nascu I, Man S, Iurian S, Popp RA, Cornean RE, Cuzmici Z, Mirea A, Grigorescu-Sido P, Pop IV. Assessment of the shox gene and chromosomal abnormalities by molecular and classical cytogenetics in patients with short stature. Acta Endocrinol (Buc) 2015; 11: 463-469.
[13]  Lazea C, Manasia R, Lazar C. Marshall syndrome – a challenge in medical practice. Paediatr Croat 2015; 59: 39-43.
[14]  Sur L, Colceriu M, Aldea CO, Sur G, Floca E. Celiac Disease a Road Paved with Many Obstacles. Differential Diagnosis in Children. International Journal of Celiac Disease 2018; 6(1): 7-10.