Biomedical Science and Engineering
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Biomedical Science and Engineering. 2015, 3(2), 35-40
DOI: 10.12691/bse-3-2-2
Open AccessReview Article

Challenges and Advances in Near Infrared Spectroscopy for Evaluating Hemodynamics in Brain

Yasutomo Nomura1,

1Department of Systems Life Engineering, Maebashi Institute of Technology, Kamisadori, Maebashi, Japan

Pub. Date: October 09, 2015

Cite this paper:
Yasutomo Nomura. Challenges and Advances in Near Infrared Spectroscopy for Evaluating Hemodynamics in Brain. Biomedical Science and Engineering. 2015; 3(2):35-40. doi: 10.12691/bse-3-2-2

Abstract

Near infrared spectroscopy is a powerful technique to evaluate hemodynamics in cerebral tissue where the light used is subject to the low scattering effect. In this wavelength range, hemoglobin has the characteristic absorption spectra. Because of the noninvasive method, this gives valuable information containing venous blood to the clinical field such as cardiac surgery, neurosurgery and pediatrics. Although the technique originates from classical biochemistry with clear solution, researchers have proposed creative ideas to be suitable for measuring hemodynamics in living tissue optically. In this mini-review, theoretical basis from Lambert-Beer law to multiwavelength method and derivation of the linear relationship between absorption and concentration of pigments from the time-resolved method are described. Furthermore the recent advances are also outlined.

Keywords:
ear infrared spectroscopy hemoglobin absorption concentration Lambert-Beer law time resolved spectroscopy

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