Biomedicine and Biotechnology
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Biomedicine and Biotechnology. 2016, 4(1), 1-4
DOI: 10.12691/bb-4-1-1
Open AccessArticle

High Prevalence of Candida albicans Observed in Asymptomatic Young Women in Owerri, Nigeria

Chijioke A. Nsofor1, , Cynthia E. Obijuru2 and Chika V. Ohalete2

1Department of Biotechnology, Federal University of Technology Owerri, Nigeria

2Department of Microbiology, Imo State University of Owerri, Nigeria

Pub. Date: September 28, 2016

Cite this paper:
Chijioke A. Nsofor, Cynthia E. Obijuru and Chika V. Ohalete. High Prevalence of Candida albicans Observed in Asymptomatic Young Women in Owerri, Nigeria. Biomedicine and Biotechnology. 2016; 4(1):1-4. doi: 10.12691/bb-4-1-1

Abstract

Candida albicans, normal flora of the vagina, is endogenous opportunistic yeast, which causes secondary infection in individuals with some underlying immune-compromised conditions. In this study, we investigated the prevalence and associated risk factors for C. albicans among asymptomatic female students of Imo State University Owerri (IMSU), southeast Nigeria. High Vaginal Swabs (HVS) specimens were randomly collected from freely consenting 284 female undergraduate students between the ages of 17 and 26 years, residing in six different hostels within the Owerri metropolis. The participants also completed a simple structured questionnaire assessing demographic data and risk factors of candidiasis. Each HVS specimen was cultured on Sabouraud Dextrose Agar (SDA) containing appropriate antibiotics to suppress bacterial growth and incubated aerobically at 37¡ãC. C. albicans was identified by conventional microbiological techniques. The overall prevalence rate of C. albicans in the HVS specimen of 284 young women studied was 37.7%, with the highest rate of 45.0% observed among students between the age group 23-25 while the lowest prevalence (20.6%) was among those between ages 17-19 years. Analysis of the participants¡¯ response to the questionnaire indicates that C. albicans carrier rate may be associated with poor personal hygiene. Statistical analysis showed that prevalence rate of C. albicans among the students from different hostels was not significantly different in any of the sampled hostels P<0.05. This study indicates that the prevalence of vaginal candida colonization among female students is highly significant. Predisposing factors such as the use of tight underwear, indiscriminate use of antibiotics should be avoided and the need for good and adequate personal hygiene should be encouraged.

Keywords:
Candida albicans female students prevalence and risk factors

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References:

[1]  Aher C.S (2014). Species distribution, virulence factors and antifungal susceptibility profile of Candida isolated from oropharyngeal lesions of HIV infected patients. Int. J. Curr. Microbiol. App. Sci; 3(1):453446.
 
[2]  Aniebo V. (1984). The effect of some Medicinal plants on Pathogenic fungi in University of Port Harcourt Rivers State. J. of Med. Sc., 2, 1-10.
 
[3]  de Oliveira J.M, Cruz A.S, Fonseca A.F, Vaz C.P, Rodrigues A, Aurea F, Maia J and Sousa J.A (1993). Prevalence of Candida albicans in vaginal fluid of asymptomatic Portuguese women. J Reprod Med. 38 (1):41-2.
 
[4]  Elmer W.K, Stephen D.A, and William MJ (1992). Laboratory approach to the diagnosis of fungal infections. 14th ed. Lipincott Co. Philadelphia.
 
[5]  Feglo K. and Narkwa P. (2012). Prevalence and Antifungal Susceptibility Patterns of Yeast Isolates at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana. British Microbiology Research Journal. 2: 10-22.
 
[6]  Jain N, Mathur P, Misra M.C, Behera B, Xess I. and Sharma, S.P. (2012). Rapid identification of yeast isolates from clinical specimens in critically ill trauma ICU patients. Journal of Laboratory Physicians. 4:30-4.
 
[7]  Kanagal D.V, Vineeth V.K, Kundapur R, Shetty H and Rajesh A (2014). Prevalence of Vaginal Candidiasis in Pregnancy among Coastal South Indian Women. J Women's Health, Issues Care, 3:6.
 
[8]  Karima Sdoudi M.E.B, Rhimou E.l, Doroth¨¦e D, Naima E, d'Enfert C, and Aziza R (2014). Phylogeny and diversity of candida albicans vaginal isolates from three continents. Int. J. Curr. Microbiol. App.;3(7):471-480.
 
[9]  Khan AS, Amir F, Altaf S, Tanveer R (2009). Evaluation of common organisms causing vaginal discharge. J. Ayub. Med. Coll.21(2):90-93.
 
[10]  Maikenti JI, Adogo LY, Zamfara KA and Nganjiwa SG (2016). The Prevalence of Vaginal Candida Colonization among Female Students in Bingham University. British Microbiology Research Journal 12(2): 1-7.
 
[11]  Muvunyi CM, and Hernandez CT (2009). Prevalence of bacterial vaginosis in women with vaginal symptoms in south province, Rwanda. Afr. J. Clin. Exper. Microbiol.10(3):156-153
 
[12]  Nwankwo EOK, Kandakai-Olukemi YT, Shuaibu SA (2010). Aetiologic agents of abnormal vaginal discharge among females of reproductive age in kano, Nigeria. Journal of Medicine and Biomedical Sciences. 12-16.
 
[13]  Onianwah I.F (2014). The Incidence and Prevalence of Candida albicans infection of the urogenital tract of females between the ages of 18 and 45 years old: A Case study of Patients receiving treatment in Ashford and Patrice clinic in Port. Int. Res. J. Environment Sci. Vol. 3(4), 101-10.
 
[14]  Oyedepo O.O, and Onasoga MF (2015). Incidence and Speciation of Candida Species among Non-gravid young Females in Ilorin, North Central, Nigeria. J. Appl. Sci. Environ. Manage. 19(4) 680-685.
 
[15]  Oyewole IO, Anyasor GN, Michael- Chikezie EC (2010). Prevalence of STI pathogens in HIV- infected and non-infected women: Implications for acquisition and transmission of HIV in Nigeria. Asian Journal of Medical Sciences. 2(3): 163-166. 33.
 
[16]  Priotta M.V. and Garland M (2006). Genital Candidaspecies detected in samples from women in Melbourne, Australi before and after treatment with antibiotics, J. of clinical Microbiology, 10(2), 16-25.
 
[17]  Rylander, E., Berglund, A.L., Krassny, C. and Petrini, B. (2004). Vulvovaginal candida in a young sexually active population: prevalence and association with oro-genital sex and frequent pain at intercourse. Sexually Transmitted Infections. 80: 54-57.
 
[18]  Sobel, J. D., Far, O.S. and Force, R.W. (1998). Vulvovaginal candidiasis: Epidemiology, diagnostic, and therapeutic considerations. American Journal of Obstetrics and Gynecology. 178: 203-211.
 
[19]  Sudberg P, Gown BJ. The district morphogenic states of Candida albicans, trends in microbiology. Int. J. STD. AIDS;13 (8):522-539.
 
[20]  Uyawah P.O.(1984). A preliminary study of an open clinical comparative evaluation of Ticonzole (trosyd) vaginal cream and tablet, N.J. Microbiol, 4, 29-33.
 
[21]  Yang Y.I. (2003) virvulence factors of candida species J., Microbiol Immunol. Infect., 36(4), 223-228.