American Journal of Pharmacological Sciences
ISSN (Print): 2327-6711 ISSN (Online): 2327-672X Website: http://www.sciepub.com/journal/ajps Editor-in-chief: Srinivas NAMMI
Open Access
Journal Browser
Go
American Journal of Pharmacological Sciences. 2017, 5(2), 25-30
DOI: 10.12691/ajps-5-2-2
Open AccessReview Article

Various Pharmacological Aspects of Cocos nucifera - A Review

Babita Aggarwal1, H. S. Lamba2, Pankaj Sharma3 and Ajeet4,

1School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India

2Department of Pharmaceutical Chemistry, H. R. Institute of Pharmacy, Ghaziabad, Uttar Pradesh, India

3School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India

4Department of Pharmaceutical Chemistry, School of Pharmacy, Vishveshwarya Group of Institute, Greater Noida, Uttar Pradesh, India

Pub. Date: June 14, 2017

Cite this paper:
Babita Aggarwal, H. S. Lamba, Pankaj Sharma and Ajeet. Various Pharmacological Aspects of Cocos nucifera - A Review. American Journal of Pharmacological Sciences. 2017; 5(2):25-30. doi: 10.12691/ajps-5-2-2

Abstract

Plant materials, derived from thousands of plant species from lichens to towering trees, represents substantial portion of the global market. When we think about the highly nutritious plant parts then we can’t move beyond Cocos nucifera. Many scientists around the world have worked on Cocos nucifera and revealed too may bioactivities such as antimicrobial, antiinflammatory, antiparasitic, antidiabetic, antineoplastic, insecticidal, and leishmanicidal activities. In this review also, we focused on various pharmacological aspects of Cocos nucifera, with different extraction methods and isolated compounds.

Keywords:
Cocos nucifera husk fiber shell pharmacological effects extraction methods

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Singh Y. N., “Traditional medicine in Fiji: some herbal folk cures used by Fiji Indians”. Journal of Ethnopharmacology, 15, 57-88, 1986.
 
[2]  Yartey J., Harisson E. K., Brakohiapa L. A., Nkrumah, F. K., “Carbohydrate and electrolyte content of some home available fluids used for oral rehydration in Ghana”. Journal of Tropical Pediatrics, 39, 234-237, 1993.
 
[3]  Selvaraj Mohana Roopan, “An Overview of Phytoconstituents, Biotechnological Applications, and Nutritive Aspects of Coconut (Cocos nucifera)”.
 
[4]  Rukmini J. N., Manasa S., Rohini C., Sireesha L. P., Ritu S., Umashankar G. K., “Antibacterial efficacy of tender coconut water (Cocos nucifera L) on Streptococcus mutans: An in-vitro study”. J Int Soc Prevent Communit Dent, 7,130-134, 2017.
 
[5]  Nidhi Tyagi, Vikas Hooda, Anjali Hooda and Sachin Malkani, “Evaluation of antidiabetic potential of ethanolic and aqueous extract of Cocos nucifera endocarp”. World Journal of Pharmacy and Pharmaceutical Sciences, 4(7), 1112-1120, 2017.
 
[6]  Elizabeth Abidemi Balogun, Sylvia Orume Malomo, Joseph Oluwatope Adebayo, Ahmed Adebayo Ishola, Ayodele Olufemi Soladoye, Lawrence Aderemi Olatunji, Olatunji Matthew Kolawole, Stephen Olubunmi Oguntoye, Abiola Samuel Babatunde, Oluwole Busayo Akinola, “In vivo antimalarial activity and toxicological effects of methanolic extract of Cocos nucifera (Dwarf red variety) husk fibre”. Journal of Integrative Medicine, 12(6), 504-511, 2014.
 
[7]  Adebayo J. O., Balogun E. A., Malomo S. O., Soladoye A. O., Olatunji L. A., Kolawole O. M., Oguntoye O. S., Babatunde A. S., Akinola O. B., Aguiar A. C. C., Andrade I. M., Souza N. B., Krettli A. U., “Antimalarial Activity of Cocos nucifera Husk Fibre: Further Studies”. Evidence-Based Complementary and Alternative Medicine.
 
[8]  Viju N., Satheesh S., Vincent S. G. P., “Antibiofilm activity of coconut (Cocos nucifera Linn.) husk fibre extract”. Saudi Journal of Biological Sciences, 20, 85-91, 2013.
 
[9]  Adebayo J. O., Santana A. E. G., Krettli A. U., “Evaluation of the antiplasmodial and cytotoxicity potentials of husk fiber extracts from Cocos nucifera, a medicinal plant used in Nigeria to treat human malaria”. Human and Experimental Toxicology, 31(3), 244-249, 2012.
 
[10]  Singla R. K., Jagani H., “Investigation of Antimicrobial Effect of Dry Distilled Extract of Cocos nucifera Linn Endocarp”. Webmed Central Pharmaceutical Sciences, 3(8), WMC003671, 2012.
 
[11]  Bidkar J. S., Poojari S. K., Dama G. Y., Bidkar S. J., “An Inhibitory Study on Oral Microflora of Homo sapiens by the Water Extract of Cocos Nucifera Shell Ash”. International Journal of Pharma Research & Development, 3(2), 171-174, 2011.
 
[12]  Zakaria Z. A., Somchit M. N., Mat Jais A. M., The L. K., Salleh M. Z., Long K., “In vivo Antinociceptive and Anti-inflammatory Activities of Dried and Fermented Processed Virgin Coconut Oil”. Med Princ Pract, 20, 231-236, 2011.
 
[13]  Taiwo Adesola Akinyele, Omobola Oluranti Okoh, David Ayinde Akinpelu, Anthony Ifeanyi Okoh, “In-Vitro Antibacterial Properties of Crude Aqueous and n-Hexane Extracts of the Husk of Cocos nucifera”. Molecules 16, 2135-2145.
 
[14]  Komala Sivakumar M., Mohammed Moideen M., Ruby Varghese, Sampath Kumar K. P., “Antibacterial potential of root and bark of Cocos nucifera linn. Against isolated urinary tract infection causing pathogens”. International Journal of Pharma and Bio Sciences, 2(4), 489-500, 2011.
 
[15]  Abdulelah H. Al-Adhroey, Zurainee M. Nor, Hesham M. Al-Mekhlafi, Adel A. Amran, Rohela Mahmud, “Evaluation of the use of Cocos nucifera as antimalarial remedy in Malaysian folk medicine”. Journal of Ethnopharmacology, 134, 988-991, 2011.
 
[16]  Hemanth Sairam Pattigadapa, Ramesh M., Praneeth Sagar C.H., Bhaskar Rao U., Lakshman G., Ankaiah M., Balu Naik J., “Cardiotonic Activity Of Coconut Water (Cocos nucifera)”. Recent Research in Science and Technology 3(4), 155-157, 2011.
 
[17]  Costa C. T. C., Bevilaqua C. M. L., Morais S. M., Camurça-Vasconcelos A. L. F., Maciel M. V., Braga R. R., Oliveira L. M. B., “Anthelmintic activity of Cocos nucifera L. on intestinal nematodes of mice”. Research in Veterinary Science, 88, 101-103, 2010.
 
[18]  Andrzej K. Bledzki, Abdullah A. Mamun, Jürgen Volk, “Barley husk and coconut shell reinforced polypropylene composites: The effect of fibre physical, chemical and surface properties”. Composites Science and Technology 70, 840-846, 2010.
 
[19]  Obidoa Onyechi, Joshua, Parker Elijah, Eze Nkechi J., “Phytochemical Analysis of Cocos nucifera L.”. Journal of Pharmacy Research, 3(2), 280-286, 2010.
 
[20]  Girish R. Bankar, Pawan G. Nayak, Punit Bansal, Piya Paul, Pai K. S. R., Rajeev K. Singla, Varadaraj G. Bhat., “Vasorelaxant and antihypertensive effect of Cocos nucifera Linn. endocarp on isolated rat thoracic aorta and DOCA salt-induced hypertensive rats”. Journal of Ethnopharmacology, 134(1), 50-54, 2011.
 
[21]  Intahphuak S., Khonsung P., Panthong A., “Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil”. Pharm Biol. 48(2), 151-157, 2010.
 
[22]  Sebastian Rinaldi, Davi O. Silva, Fabiana Bello, Celuta S. Alviano, Daniela S. Alviano, Maria Eline Matheus, Patricia D. Fernandes, “Characterization of the antinociceptive and anti-inflammatory activities from Cocos nucifera L. (Palmae)”. Journal of Ethnopharmacology 122, 541-546, 2009.
 
[23]  Oliveira L. M. B., Bevilaqua C. M. L., Costa C. T. C., Macedo I. T. F., Barros R. S., Rodrigues A. C. M., Camurc¸ a-Vasconcelos A. L. F., Morais S. M., Lima Y. C., Vieira L. S., Navarro A. M. C., “Anthelmintic activity of Cocos nucifera L. against sheep gastrointestinal nematodes”. Veterinary Parasitology, 159, 55-59, 2009.
 
[24]  Moumita Chakraborty, Adinpunya Mitra., “The antioxidant and antimicrobial properties of the methanolic extract from Cocos nucifera mesocarp”. Food Chemistry, 107, 994-999, 2008.
 
[25]  Pallavi Srivastava, Durgaprasad S., “Burn wound healing property of Cocos nucifera: An appraisal”. Indian J Pharmacol, 40(4), 144-146, 2008.
 
[26]  Koschek P. R., Alviano D. S., Alviano C. S., Gattass C. R., “The husk fiber of Cocos nucifera L. (Palmae) is a source of anti-neoplastic activity”. Brazilian Journal of Medical and Biological Research, 40, 1339-1343, 2007.
 
[27]  Sueli Rodrigues, Gustavo A.S. Pinto, “Ultrasound extraction of phenolic compounds from coconut (Cocos nucifera) shell powder”. Journal of Food Engineering, 80, 869-872, 2007.
 
[28]  Zakaria, Z. A., Reezal I., Jais A. M. M., Somchit M. N., Sulaiman M. R., et al., “The anti-inflammatory, anti-pyretic and wound healing activities of Cocos nucifera (MATAG Types) fresh juice and kernel extract in experimental animals”. J. Pharmacol. Toxicol., 1,516-526, 2006.
 
[29]  Gargi Dey, Moumita Chakraborty, Adinpunya Mitra, “Profiling C6–C3 and C6–C1 phenolic metabolites in Cocos nucifera”. Journal of Plant Physiology 162, 375-381, 2006.
 
[30]  Daniela S. Alviano, Karen F. Rodrigues, Suzana G. Leitão, Marcio L. Rodrigues, Maria Eline Matheus, Patrıcia D. Fernandes, Angelo R. Antoniolli, Celuta S. Alviano. “Antinociceptive and free radical scavenging activities of Cocos nucifera L. (Palmae) husk fiber aqueous extract”. Journal of Ethnopharmacology, 92, 269-273, 2004.
 
[31]  Ricardo R. Mendonça-Filho, Igor A. Rodrigues, Daniela S. Alviano, André L. S. Santos, Rosangela M. A. Soares, Celuta S. Alviano, Angela H. C. S. Lopes, Maria do Socorro S. Rosa., “Leishmanicidal activity of polyphenolic-rich extract from husk fiber of Cocos nucifera Linn. (Palmae)”. Research in Microbiology, 155, 136-143, 2004.
 
[32]  Gargi Dey, Ashish Sachan, Shashwati Ghosh, Adinpunya Mitra, “Detection of major phenolic acids from dried mesocarpic husk of mature coconut by thin layer chromatography”. Industrial Crops and Products, 18, 171-176, 2003.