American Journal of Pharmacological Sciences
ISSN (Print): 2327-6711 ISSN (Online): 2327-672X Website: http://www.sciepub.com/journal/ajps Editor-in-chief: Srinivas NAMMI
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American Journal of Pharmacological Sciences. 2014, 2(5B), 17-22
DOI: 10.12691/ajps-2-5B-5
Open AccessResearch Article

Role of Pharmacist in Improving Health Related Quality of Life (HRQoL) in Hypertensive Pateints in Pakistan

Muhammad Masoom Akhtar1, , Akbar Waheed2, Dilnawaz Sheikh3 and Azhar Hussain1

1Department of Pharmacy, Hamdard Institute of Pharmaceutical Sciences, Islamabad, Pakistan

2Department of Pharmacology, Army Medical College, Rawalpindi, Pakistan

3Faculty of Pharmacy, Hamdard University, Sharae Madina Al Hikmah,Karachi, Pakistan

Pub. Date: December 04, 2014
(This article belongs to the Special Issue Optimizing Patient Care through Effective Pharmacy Practice Models)

Cite this paper:
Muhammad Masoom Akhtar, Akbar Waheed, Dilnawaz Sheikh and Azhar Hussain. Role of Pharmacist in Improving Health Related Quality of Life (HRQoL) in Hypertensive Pateints in Pakistan. American Journal of Pharmacological Sciences. 2014; 2(5B):17-22. doi: 10.12691/ajps-2-5B-5

Abstract

Health related quality of life (HRQoL) is used to measure both the present health status and the impact of health care interventions on the patients. The aim of the present study is to evaluate the improvement in health related quality of life of the hypertensive patients after pharmaceutical care provided by pharmacist in Pakistan. A repeated measure prospective intervention study was conducted at Armed Forces Institute of Cardiology, Rawalpindi, Pakistan. 286 hypertensive patients were enrolled at baseline, out which 116 patients kept enrolled till the end of the study. After taking the demographic data at baseline, the health related quality of life was measured by using the Urdu version of generic EQ-5D instrument of Euroqol Group at baselines and follow up visits after 2 months, 4 months and 6 months. All the data was entered and analyzed by using SPSS version 16. Paired t test and Pearson’s correlation coefficient were performed to compare EQ-5D values and association between baselines and follow up visits. The EQ-5D Index score and EQ-5D VAS score were 0.8789 ± 0.17993 and 65.56 ± 16.67 at baseline which were raised to 0.9276 ± 0.1392 and 78.00 ± 12.649 respectively after 6 months. The study showed that health related quality of life of these hypertensive patients were significantly improved after pharmaceutical care interventions.

Keywords:
Diastolic blood pressure (DBP) EuroQol five-dimension scale (EQ-5D) Health related quality of life (HRQoL) Systolic blood pressure (SBP)

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Dolan, P., et al., A social tariff for EuroQol: results from a UK general population survey. 1995: Centre for Health Economics University of York, UK.
 
[2]  Theodorou, M., et al., Quality of life measurement in patients with hypertension in cyprus. The Hellenic Journal of Cardiology, 2011. 52(5): p. 407-415.
 
[3]  Erickson, S.R., B.C. Williams, and L.D. Gruppen, Relationship Between Symptoms and HealthRelated Quality of Life in Patients Treated for Hypertension. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2004. 24(3): p. 344-350.
 
[4]  Norman, G.R., J.A. Sloan, and K.W. Wyrwich, Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Medical care, 2003. 41(5): p. 582-592.
 
[5]  Wilson, I.B. and P.D. Cleary, Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes. Jama, 1995. 273(1): p. 59-65.
 
[6]  WHO, A., Global Brief on Hypertension. World Health Organization, 2013.
 
[7]  Schipper, H., J. Clinch, and C.L. Olweny, Quality of life studies: definitions and conceptual issues. Quality of life and pharmacoeconomics in clinical trials, 1996. 2: p. 11-23.
 
[8]  Hayes, D.K., et al., Health-related quality of life and hypertension status, awareness, treatment, and control: National Health and Nutrition Examination Survey, 2001-2004. Journal of hypertension, 2008. 26(4): p. 641-647.
 
[9]  Trevisol, D.J., et al., Health-related quality of life and hypertension: a systematic review and meta-analysis of observational studies. Journal of hypertension, 2011. 29(2): p. 179-188.
 
[10]  Korhonen, P.E., et al., Health-related quality of life and awareness of hypertension. Journal of hypertension, 2011. 29(11): p. 2070-2074.
 
[11]  Poljičanin, T., et al., Diabetes mellitus and hypertension have comparable adverse effects on health-related quality of life. BMC Public Health, 2010. 10(1): p. 12.
 
[12]  Hepler, C.D. and L.M. Strand, Opportunities and responsibilities in pharmaceutical care. Am J Hosp Pharm, 1990. 47(3): p. 533-43.
 
[13]  Planas, L.G., et al., A pharmacist model of perceived responsibility for drug therapy outcomes. Social science & medicine, 2005. 60(10): p. 2393-2403.
 
[14]  Lyra Jr, D.P., et al., Influence of Pharmaceutical Care intervention and communication skills on the improvement of pharmacotherapeutic outcomes with elderly Brazilian outpatients. Patient Education and Counseling, 2007. 68(2): p. 186-192.
 
[15]  Júnior, L., P.S. Marcellini, and I.R. Pelá, Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension. Revista Brasileira de Ciências Farmacêuticas, 2008. 44(3): p. 451-457.
 
[16]  Lee, J.K., K.A. Grace, and A.J. Taylor, Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol. JAMA: the journal of the American Medical Association, 2006. 296(21): p. 2563-2571.
 
[17]  Zillich, A.J., et al., Hypertension outcomes through blood pressure monitoring and evaluation by pharmacists (HOME study). Journal of general internal medicine, 2005. 20(12): p. 1091-1096.
 
[18]  Vivian, E.M., Improving blood pressure control in a pharmacistmanaged hypertension clinic. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2002. 22(12): p. 1533-1540.
 
[19]  Roter, D.L., et al., Effectiveness of interventions to improve patient compliance: a meta-analysis. Medical care, 1998. 36(8): p. 1138-1161.
 
[20]  Morisky, D.E., et al., Predictive validity of a medication adherence measure in an outpatient setting. The Journal of Clinical Hypertension, 2008. 10(5): p. 348-354.
 
[21]  Carter, B.L., et al., Evaluation of hypertensive patients after care provided by community pharmacists in a rural setting. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1997. 17(6): p. 1274-1285.
 
[22]  Pickard, A.S., J.A. Johnson, and K.B. Farris, The impact of pharmacist interventions on health-related quality of life. The Annals of pharmacotherapy, 1999. 33(11): p. 1167-1172.
 
[23]  Krousel-Wood, M., et al., Medication adherence: a key factor in achieving blood pressure control and good clinical outcomes in hypertensive patients. Current opinion in cardiology, 2004. 19(4): p. 357-362.
 
[24]  Page, I.H., Drug treatment of hypertension. 1966: Springer.
 
[25]  Saleem, F., M.A. Hassali, and A.A. Shafie, A crosssectional assessment of healthrelated quality of life (HRQoL) among hypertensive patients in Pakistan. Health Expectations, 2012.
 
[26]  Palaian, S., et al. (2005) Role of pharmacist in counseling diabetes patients. The Internet Journal of Pharmacology 4.
 
[27]  Khanal, S., et al., Oncology pharmacy practice in a teaching hospital in Nepal. Journal of Oncology Pharmacy Practice, 2010. 16(2): p. 75-79.
 
[28]  EuroQol, G., EuroQol--a new facility for the measurement of health-related quality of life. Health policy (Amsterdam, Netherlands), 1990. 16(3): p. 199.
 
[29]  Dolan, P., Modeling valuations for EuroQol health states. Medical care, 1997. 35(11): p. 1095-1108.
 
[30]  Leventhal, H. and D.R. Nerenz, A model for stress research with some implications for the control of stress disorders, in Stress reduction and prevention. 1989, Springer. p. 5-38.
 
[31]  Lam, C.L. and I.J. Lauder, The impact of chronic diseases on the health-related quality of life (HRQOL) of Chinese patients in primary care. Family Practice, 2000. 17(2): p. 159-166.
 
[32]  Pyorala, K., J. Salonen, and T. Valkonen, Trends in coronary heart disease mortality and morbidity and related factors in Finland. Cardiology, 1985. 72(1-2): p. 35-51.
 
[33]  WHO, WHOQOL-BREF: introduction, administration, scoring and generic version of the assessment: field trial version, December 1996. 1996.
 
[34]  Saleem, F., M.A. Hassali, and A.A. Shafie, A cross-sectional assessment of health-related quality of life (HRQoL) among hypertensive patients in Pakistan. Health Expectations, 2012.
 
[35]  Ul Haq, N., et al., A cross sectional assessment of health related quality of life among patients with Hepatitis-B in Pakistan. Health Qual Life Outcomes, 2012. 10(1): p. 91.