[1] | Purvis K, Christiansen E. 1992. Male infertility: Current concepts. Ann. Med. 24: 259-272. |
|
[2] | Rabin DS, Qadeer U, Steir VE. 1996. A cost and outcome model of fertility treatment in a managed care environment. Fertil Steril. 66 (6): 896-903. |
|
[3] | Thonneau P, Marchand S, Tallec A, Ferial ML, Ducot B, Lansac J, et al. 1989. Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988-1989) Hum Reprod. 6(6):811-6. |
|
[4] | Singh K, Jaiswal D. 2011. Human male infertility: a complex multifactorial phenotype. Reprod Sci. 18 (5):418-25. |
|
[5] | Natali A, Turek PJ. 2011.An assessment of new sperm tests for male infertility. Urology. 77 (5): 1027-34. |
|
[6] | Cardona Maya WD, Berdugo Gutierrez JA, de los Rios J, Cadavid Jaramillo AP. 2007. Functional evaluation of sperm in Colombian fertile men. Arch Esp Urol. 60: 827-31. |
|
[7] | Rodriguez-Martinez H. 2003. Laboratory semen assessment and prediction of fertility: still utopia? Reprod Domest Anim, 38: 312-318. |
|
[8] | Brooks JD. Anatomy of the lower urinary tract and male genitalia. In: Kavoussi LR, Novick AC, Partin AW, Peters CA, Wein AJ, eds. Campbell’s Urology. 9th ed. Saunders Elsevier; 2007: 38-80. |
|
[9] | Sharpe RM. Paracrine control of the testis. Clin Endocrinol Metab. 1986; 15 (1):185-207. |
|
[10] | Tanrikut C, Schlegel PN. 2007. Antidepressant-associated changes in semen parameters. Urology 69: 185.e5-185.e7. |
|
[11] | Hayashi T, Yoshida S, Yoshinaga A, Ohno R, Ishii N, Yamada T. 2005. Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin. Scand J Urol Nephrol. 39(5):431-2. |
|
[12] | Sham, H. L., Kempf, D. J., Molla, A. 1998. ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrobial Agents and Chemotherapy, 42, 3218-24. |
|
[13] | Oldfield V, Plosker G. Lopinavir/Ritonavir. 2006. A review of its use in the management of HIV infection. Drugs, 9:1275-1299. |
|
[14] | Chandwani A, Shutter J. 2008. Lopinavir/ritonavir in the treatment of HIV-1 infection: a review. Ther. Clin. Risk Man. 4:1023-1033 |
|
[15] | Elias, A. Brambaifa, N Oputiri. D and Oru-Bo P. G. 2013 Antiretroviral toxicity and oxidative stress American Journal of Pharmacology and Toxicology, 8 (4): 187-196. |
|
[16] | Wensing, A., van Maarseveen. N and Nijhuis M. 2010. Fifteen years of HIV protease inhibitors: Raising the barrier to resistance. Antiviral Res. 85: 59-74. |
|
[17] | Palella FJ, K. M. Delaney A. C. Moorman 1998. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med.338: 853-860. |
|
[18] | Then R, P. Angehm, 1976, Nature of the bactericidal action of sulfonamides and trimethoprim, alone and in combination. J Infect Dis, 128: S498-501. |
|
[19] | Justice AC. 2006. Prioritizing primary care in HIV: comorbidity, toxicity, and demography. Top HIV Med. 14(5): 159-63. |
|
[20] | Vilar F, S. Khoo, T. TWalley. 1999. The management of Pneumocystis carinii pneumonia. Br J Clin Pharmacol. 47 (6):605-9. |
|
[21] | Hargraves C. A Rogers S, Hill F, Rahman F, Howell RS, Homa ST. 1998. Effects of Cotrimoxazole, erythromycin, amoxicillin tetracycline and chlroquine on sperm function in vitro Human Repro. 13;17, 1878-1886. |
|
[22] | Schrooten, W., Colebunders, R., Youle, M., 2001. Sexual dysfunction associated with protease inhibitors containing highly active antiretroviral treatment. AIDS, 15, 1019-1023. |
|
[23] | Olayemi F. 2010. A review on some causes of male infertility. Afri. Jour. of Biotec Vol 9: 20, 2834-2842. |
|
[24] | Yániz JL, Marco-Aguado MA, Mateos JA, Santolaria P. 2010. Bacterial contamination of ram semen, antibiotic sensitivities, and effects on sperm quality during storage at 15°C. Anim Reprod Sci. 122 (1-2): 142-9. |
|
[25] | Kielhofner, M A. 1990. Trimethoprim- Sulfamethoxazole: Pharmacokinetics, Clinical Uses, and Adverse Reactions Tex Heart Inst J. 17(2): 86-93. |
|
[26] | Hull M. W, M. Harris, V. Lima, et al. 2009. Lopinavir/ritonavir pharmacokinetics in a substitution of high-dose soft-gelatin capsule to tablet formulation. J Clin Pharmacol. 49: 155-61 |
|
[27] | Reyskens KMSE, T. L. Fisher, J. C. Schisler, O’Connor WG, Rogers AB, 2013. Cardio-Metabolic Effects of HIV Protease Inhibitors (Lopinavir/ Ritonavir), PLoS ONE, 8(9): e73347. |
|
[28] | Nathiya. S, and Nandhini.A, 2014 Evaluation of antioxidant effect of Salacia oblonga against aluminum chloride induced visceral toxicity in albino rats Int J Basic Clin Pharmacol. 3(2):315-319. |
|
[29] | Draper H. H, M. Hadley. 1990. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 186: 421-431. |
|
[30] | Beauchamp C, I. Fridovich. 1971. Superoxide dismutase: improved assays and an assay applicable to acryl amide gels. Anal. Biochem. 44: 276-287. |
|
[31] | World Health Organization (WHO). WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4 th ed. United Kingdom: Cambridge University Press; 1999. |
|
[32] | Wyrobek AJ, Bruce WR. 1975. Chemical induction of sperm abnormalities in mice. Proc Natl Acad Sci USA. 72(11): 4425-4429. |
|
[33] | Narayana K, D’souza UJ, SeetharamaRao KP. 2002. Ribavirin-induced sperm shape abnormalities in Wistar rat. Mutat Res. 513(1-2): 193-196. |
|
[34] | Drury, R.A.B., E.A. Wallington and R. Cameron, 1967. Carleton's Histological Techniques. 4th Edn., Oxford University Press, NY. USA, pp: 279-280. |
|
[35] | Ahtiainen M, Toppari J, Poutanen M, Huhtaniemi I. 2004. Indirect Sertoli cell-mediated ablation of germ cells in mice expressing the inhibin-alpha promoter/herpes simplex virus thymidine kinase transgene. Biol Reprod. 71(5): 1545-1550. |
|
[36] | Boe-Hansen GB, Morris ID, Ersbøll AK, Greve T, Christensen P. 2005. DNA integrity in sexed bull sperm assessed by neutral Comet assay and sperm chromatin structure assay. Theriogenology. 63(6): 1789-1802. |
|
[37] | Elias A. and B. Nelson, 2012. Toxicological effect of ciprofloxacin on testicular function of male guinea pigs, Asian Jour. Bio Sci. 3(2); 384-390. |
|
[38] | Ogbuehi,I, E, Adikwu and D. Oputiri. 2014. Effect of Acalypha wilkesiana MuellArg Leaf Extract on the Oxidative Indices, Liver Enzymes and Liver Integrity of Rats Infected with Plasmodium berghei British Journal of Pharmacology and Toxicology. 5(2): 68-74, 2014. |
|
[39] | Adaramoye, O. 2012 Studies on the toxicological effect of nevirapine, an antiretroviral drug, on the liver, kidney and testis of male Wistar rats. Source: A. Human & Experimental Toxicology Volume, 31 (7); 676-685. |
|
[40] | Olufadekemi YR, Kunle- Alabi SB, Gbadegesin Awobayo F. O. 2007. Impart of alpha tocopherol on metronidazole and tetracycline induced alterations in reproductive activities of male reproductive activities of male Albino rats Jour. of Biol. Sci. 2007; 7; 41-46. |
|
[41] | Adaramoye. O. A, Akanni, O. O. Farombi, E. O, 2012. Nevirapine induces testicular toxicity in Wistar rats: reversal effect of kolaviron (biflavonoid from Garcinia kola seeds) Journal of Basic and Clinical Physiology and Pharmacology. 24, (4) 313–320. |
|
[42] | Chitra KC, Latchoumycandane C, Mathur PP. 2003. Induction of oxidative stress by bisphenol A in the epididymal sperm of rats. Toxicology. 185:119-27. |
|
[43] | Fujii J, Iuchi Y, Matsuki S, Ishii T. 2003. Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues. Asian J Androl. 5: 231-42. |
|
[44] | Kumar SG, Narayana K, Bairy KL, D’souza UJ, Samuel VP, Gopalakrishna K. 2006. Dacarbazine induces genotoxic and cytotoxic germ cell damage with concomitant decrease in testosterone and increase in lactate dehydrogenase concentration in the testis. Mutat Res. 607(2): 240-252. |
|
[45] | Dondero F, Rossi T, D’Offizi G, Mazzilli F, Rosso R, Sarandrea N, Pinter E, Aiuti F. 1996. Semen analysis in HIV seropositive men and in subjects at high risk for HIV infection. Hum Reprod. 11: 765-768. |
|
[46] | Nicopoullos JD, Almeida PA, Ramsay JW, Gilling-Smith C. 2004. The effect of human immunodeficiency virus on sperm parameters and the outcome of intrauterine insemination following sperm washing. Hum Reprod. 19: 2289-2297. |
|
[47] | Lange, D. and Schirren, C. 1974. Studies on the influence of trimethoprim/ sulfamethoxazole on the quality of sperm in andrologic patients and a contribution to the pharmacological testing of a drug on the spermatogenic activity of the testis. Z. Hautkr : 49, 863-878. |
|
[48] | Abd-Allah AR, Aly HA, Mustafa AM, Abdel-Aziz AA, 2002. Hamada FM. Adverse testicular effects of some quinolone members in rats. Pharmacol Res. (41): 211-219. |
|
[49] | Khaki A, Heidari M, Ghaffari Novin M, Khaki AA. 2008. Adverse effect of ciprofloxacin on testes apoptosis and sperm parameters in rats. IJRM. 6(2): 71-76. |
|
[50] | Acacio BD, Gottfried T, Israel R, Sokol RZ. 2000. Evaluation of a large cohort of men presenting for a screening semen analysis. Feril Steril. 73(3): 595-597 |
|
[51] | Crittenden JA, Handelsman DJ, Stewart GJ. 1992. Semen analysis in human immunodeficiency virus infection. Fertil Steril. 57: 1294-1299. |
|
[52] | Dulioust E, Du AL, Costagliola D, Guibert J, Kunstmann JM, Heard I, Juillard JC, Salmon D, Leruez-Ville M, Mandelbrot L, Rouzioux C, Sicard D, Zorn JR, Jouannet P, De Almeida M. 2002. Semen alterations in HIV-1-infected men. Hum Reprod. 17: 2112-2118. |
|
[53] | White IG. 1954. The toxicity of some antibacterials for bull, ram, rabbit and human spermatozoa. Aust. J. Exp. Biol. Med. Sci 32, 41-48. |
|
[54] | Elias A. and B. Nelson 2012. Toxicological effect of perfloxacin on testicular function of male guinea pigs Asian Jour. Bio. Sci. 3(1); 28-33. |
|
[55] | White DJ, Mital D, Taylor S, St John JC. 2001. Sperm mitochondrial DNA deletions as a consequence of long term highly active antiretroviral therapy. Aids. 15: 1061-1062. |
|
[56] | Casula M, Weverling GJ, Wit FW, Timmermans EC, Stek M Jr, Lange JM, et al. 2005. Mitochondrial DNA and RNA increase in peripheral blood mononuclear cells from HIV-1-infected patients randomized to receive stavudine-containing or stavudine- sparing combination therapy. J Infect Dis, 192: 1794-1800. |
|
[57] | van Leeuwen E, Wit FW, Repping S, Eeftinck Schattenkerk JKM, Reiss P, van der Veen F, Prins JM. 2008. Effects of antiretroviral therapy on semen quality. AIDS. 22: 637-642. |
|
[58] | Cuzick DS, Overstreet J.W, Factor Litva PK, Brazil CK, et al., 2001. Sperm morphology, motility and concentration in fertile and infertile men N.Engl. Med. 345; 1388-1393. |
|
[59] | Robbins WA, Witt KL, Haseman JK, Dunson DB, Troiani L, Cohen MS, 2001. Antiretroviral therapy effects on genetic and morphologic end points in lymphocytes and sperm of men with human immunodeficiency virus infection. J Infect Dis 2001; 184: 127-135. |
|
[60] | Toovey S., Hudson E. Hendry WF, and Levi AJ. 1981. Sulfasalazine and male infertility reversibility and possible mechanism Gut. 22: 445-451. |
|
[61] | Alonso. V. Linares V. Belles M. Albina ML, Sirvent JJ. 2009. Sulfasalazine induced oxidative stress; Apossible mechanism of male infertility. Repro. Tox. 27; 35-40. |
|
[62] | Elias A. and B. Nelson 2012. Subchronic evaluation of ciprofloxacin and perfloxacin on spermatic parameters of male guinea pigs Asian Jour. Bio. Sci. 3(2); 595-601. |
|
[63] | Chris-Ozoko LE, Charity AA, Ekundina VO. 2013. Histomorphological effect of zidovudine on the testes of adult male wistar rats (rattus novegicus). J Basic Clin Reprod Sci; 2:73-6. |
|
[64] | Lewis W, Day BJ, Copeland WC. Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. Nat Rev Drug Discov. 2003; 2: 812-822. |
|
[65] | Pollman, M.J., T. Yamada, M. Horiuchi and G.H. Gibbons. 1996. Vasoactive substances regulate vascular smooth muscle cell apoptosis: countervailing influences of nitric oxide and angiotensin II,” Circulation Research; 79 (4)748-756, 1996. |
|