American Journal of Pharmacological Sciences
ISSN (Print): 2327-6711 ISSN (Online): 2327-672X Website: http://www.sciepub.com/journal/ajps Editor-in-chief: Srinivas NAMMI
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American Journal of Pharmacological Sciences. 2019, 7(1), 1-4
DOI: 10.12691/ajps-7-1-1
Open AccessArticle

Ichnocarpus frutescens Stem Extract: Effect of Different Concentrations of Solvent on Total Phenol Content, Total Flavonoid Content and on Its Antioxidant Activity

Babita Aggarwal1, Antariksh Katara2, Harsh Raghav3, Santosh Kumar Verma4 and Ajeet4,

1School of Pharmacy, Vishveshwarya Group of Institutions, Greater Noida, India

2Agri, Food and Life Sciences Lab, CEG Test House and Research Centre Pvt. Ltd., Jaipur, Rajasthan

3Department of Pharmaceutics, HR Institute of Pharmacy, Ghaziabad, India

4Faculty of Pharmaceutical Sciences, Motherhood University, Roorkee, India

Pub. Date: April 01, 2019

Cite this paper:
Babita Aggarwal, Antariksh Katara, Harsh Raghav, Santosh Kumar Verma and Ajeet. Ichnocarpus frutescens Stem Extract: Effect of Different Concentrations of Solvent on Total Phenol Content, Total Flavonoid Content and on Its Antioxidant Activity. American Journal of Pharmacological Sciences. 2019; 7(1):1-4. doi: 10.12691/ajps-7-1-1

Abstract

Free radicals formed from reactive oxygen species can oxidize biomolecules leading to tissue injury and cell death. Oxidative stress is generated by imbalance between reactive oxygen species and antioxidants. Hence, to overcome this problem, an attempt has been drawn by studying Ichnocarpus frutescens stem extract. In order to study it we have gone through total phenolic content, total flavonoid content as quantification of secondary metabolite. As far as antioxidant activity concerns, DPPH radical scavenging, reducing power assay and total antioxidant activity were performed and analyzed. During this analysis, we have found that 80% ethanol showed maximum activity as compared to 50% and 95% ethanolic extract of Ichnocarpus frutescens stem.

Keywords:
total phenolic content total flavonoid content free radical oxidative stress reducing power radical scavenging

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