American Journal of Medical Sciences and Medicine
ISSN (Print): 2327-6681 ISSN (Online): 2327-6657 Website: http://www.sciepub.com/journal/ajmsm Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Medical Sciences and Medicine. 2017, 5(2), 27-34
DOI: 10.12691/ajmsm-5-2-2
Open AccessArticle

Some Biochemical Changes during Summer Islamic Fasting in Diseased Patients in Comparison with Normal

Nadya GH. AbdulKareem1, , Nawar S. Khalil2, Abdullah E Jasim3 and Muzahim Alkabban1

1Department of Biochemistry, College of Medicine, Al-Iraqia University, Baghdad, Iraq

2Department of Community Medicine, College of Medicine, Al-Iraqia University, Baghdad, Iraq

3Department of Internal Medicine, College of Medicine, Al-Iraqia University, Baghdad, Iraq

Pub. Date: May 02, 2017

Cite this paper:
Nadya GH. AbdulKareem, Nawar S. Khalil, Abdullah E Jasim and Muzahim Alkabban. Some Biochemical Changes during Summer Islamic Fasting in Diseased Patients in Comparison with Normal. American Journal of Medical Sciences and Medicine. 2017; 5(2):27-34. doi: 10.12691/ajmsm-5-2-2

Abstract

Some biochemical parameters in serum of diabetic, hypertensive and hypothyroid patients are estimated pre and post summer Islamic fasting in comparison with healthy control. Sixteen diseased patients (3 male and 13 female) with twelve healthy control persons (3 male and 9 female) at a mean age of (43 ± 8.22 years) and (37.5 ± 10.81 years) respectively. Proper history and blood sample were collected from all subscribers in the first and last day of Ramadan. Patients group demonstrate significant decrease in fasting blood glucose (FBG) level, blood urea, serum creatinine, and uric acid (as an improvement of kidney function), total and direct serum bilirubine and aspartate transaminase (AST) (indicate improvement of liver detoxification and excretion capacity) in addition to significant elevation of high density lipoprotein (HDL) levels during Ramadan. Healthy subjects show decrease in the body weight; with significant decrease in FBG, alkaline phosphatase (ALP), AST and significant increase in the HDL. All previous results clinically insignificant as they are not deviated from the normal reference ranges, meanwhile they are considered as good factors for controlling lipids, diabetes, hypertension and other diseases related to kidneys or liver during Ramadan, moreover health benefit in non-diseased subjects.

Keywords:
islamic fasting transaminases FBG kidney function and lipid profile tests

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Bahman Mirzaei, Farhad Rahmani-Nia, Mahdi Ghahremani Moghadam, et al. The Effect of Ramadan Fasting on Biochemical and Performance Parameters in Collegiate Wrestlers. Iran J Basic Med Sci. 2012; 15(6): 1215-1220.
 
[2]  Dr. Biodun Awosusi: 10 Incredible Health Benefits of Fasting. 2012.
 
[3]  Mohammed A Jaleel, Farah N Fathima, Bushra N.F. Jaleel, Nutrition, energy intake- output, exercise, and fluid homeostasis during fasting in Ramadan. J of medical nutrition & nutraceuticals. 2013; 2 (2): 63-68.
 
[4]  E Ural, G Kozdag, T Kilic, et al. The effect of Ramadan fasting on ambulatory blood pressure in hypertensive patients using combination drug therapy. Journal of Human Hypertension. 2008; 22, 208-210.
 
[5]  Syed A. Raza, Osama Ishtiaq, A. G. Unnikrishnan, A. K. Azad Khan, et al., Thyroid diseases and Ramadan. Indian J Endocrinol Metab.2012; 16(4): 522-524.
 
[6]  Toda, Masahiro, Morimoto, Kanehisa, “Ramadan Fasting - Effect on Healthy Muslims”, Social Behavior and Personality: an international journal. 2004.
 
[7]  Al Hourani H, Atoum M, Akel S, Hijjawi N, Awawdeh S. Effects of Ramadan fasting on some haematological and biochemical parameters. Jordan Journal of Biological Sciences 2009; 2: 103-108.
 
[8]  Song WO, Chun OK, Obayashi S, Cho S, Chung CE. Is consumption of breakfast associated with body mass index in US adults? J Am Diet Assoc. 2005; 105(9): 1373-82.
 
[9]  Masheb RM, Grilo CM. Eating patterns and breakfast consumption in obese patients with binge eating disorder. Behav Res Ther. 2006; 44(11): 1545-53.
 
[10]  Ola A. El-Gendy M. Rokaya, Hassan E. El-Batae and Salwa Tawfeek. Ramadan Fasting Improves Kidney Functions and Ameliorates Oxidative Stress in Diabetic Patients. World Journal of Medical Sciences. 2012; 7 (1): 38-48.
 
[11]  Bouhlel E, Zaouali M, Miled A, Tabka Z, et al., Ramadan fasting and the GH/IGF-1 axis of trained men during submaximal exercise; Ann Nutr Metab.2008; 52(4): 261-6.
 
[12]  David Stipp. How intermittent fasting might help you live a longer and healthier life. Intermittent fasting might improve health, but clinical data are thin. Scientific American Online; 2013.
 
[13]  Farooq N, Priyamvada S, Arivarasu NA, et al. Influence of Ramadan-type fasting on enzymes of carbohydrate metabolism and brush border membrane in small intestine and liver of rat used as a model. Br J Nutr. 2006; 96(6):1087-94.
 
[14]  Shilpa B. Asegaonkara, Ishrat Kareemb , JayshreeS. Bavikar et al. Effect of Ramadan Fasting on Renal Function Markers in Healthy Adults From Aurangabad. WIMJOURNAL 2014; 1(1): 2349-2910.
 
[15]  Seyyed Reza Attarzadeh Hosseini, Mohammad Ali Sardar, Keyvan Hejazi, and Samaneh FarahatInt. The Effect of Ramadan Fasting and Physical Activity on Body Composition, Serum Osmolarity Levels and Some Parameters of Electrolytes in Females. J Endocrinol Metab. 2013; 11(2): 88-94.
 
[16]  Azizi F. Research in Islamic fasting and health. Ann Saudi Med 2002; 22: 186-91.
 
[17]  Mohammad Zafar A. Nomani. Dietary fat, blood cholesterol and uric acid levels during Ramadan fasting. IslamiCity. 2016.
 
[18]  Jafar Nasiri, Soleiman Kheiri, Abolfazl Khoshdel, and Amirgholi Jafari Boroujeni. Effect of Ramadan Fast on Liver Function Tests. Iran J Med Sci. 2016; 41(5): 459-460.
 
[19]  Dr. Ishrat Kareem Dhule. Dr. Jayshree Bavikar Dr. Shilpa Asegaonkar. Effect of Ramadan fasting on hepatic function in healthy adults. Indian journal of research 2016; 5(3).
 
[20]  MAF El-Hazmi, FZ Al-Faleh, IB Al-Mofleh. Effect of Ramadan fasting on the values of hematological and biochemical parameters. Saudi Med J. 1987; 8: 171-76.
 
[21]  MH Hallak, MZA Nomani. Body weight loss and changes in blood lipid level in normal men on hypocaloric diets during Ramadan fasting. Am J Clin Nutr. 1988; 8:1197-1210.
 
[22]  Salahuddin M, Sayed Ashfak AH, Syed SR, and Badaam KM. Effect of Ramadan fasting on body weight, (BP) and biochemical parameters in middle aged hypertensive subjects: An observational trial. Clin Diagn Res. 2014; 8(3): 16-18.
 
[23]  Aksungar FB, Eren A, Ure S, Teskin O, Ates G. Effects of intermittent fasting on serum lipid levels, coagulation status and plasma homocysteine levels. Ann Nutr Metab. 2005; 49(2): 77-82.
 
[24]  Aksungar FB, Topkaya AE, Akyildiz M. Interleukin-6, C-reactive protein and biochemical parameters during prolonged intermittent fasting. Ann Nutr Metab. 2007; 51: 88-95.
 
[25]  Ziaee V, Razaei M, Ahmadinejad Z, et al., The changes of metabolic profile and weight during Ramadan fasting Singapore Med J. 2006; 47(5): 409-14.