American Journal of Medical Sciences and Medicine
ISSN (Print): 2327-6681 ISSN (Online): 2327-6657 Website: Editor-in-chief: Apply for this position
Open Access
Journal Browser
American Journal of Medical Sciences and Medicine. 2019, 7(5), 198-200
DOI: 10.12691/ajmsm-7-5-3
Open AccessArticle

Case Fatality Rate of Colorectal Cancer in Nineveh

Moayad Aziz Alabdaly1, , Faris Mahmode Lolan2 and Salah Ali Mahmood Al Ashow3

1Department of Family and Community Medicine, College of Medicine, University of Nineveh

2Department of Internal Medicine, College of Medicine, University of Nineveh

3Department of Family and Community Medicine, College of Medicine, University of Mosul

Pub. Date: December 25, 2019

Cite this paper:
Moayad Aziz Alabdaly, Faris Mahmode Lolan and Salah Ali Mahmood Al Ashow. Case Fatality Rate of Colorectal Cancer in Nineveh. American Journal of Medical Sciences and Medicine. 2019; 7(5):198-200. doi: 10.12691/ajmsm-7-5-3


Background: Colorectal cancer is the third most common cancer in men and the second in women, according to the latest GLOBOCAN worldwide estimation, and the second most common cause of death. Aim of the study: This study aims to investigate the case fatality rates of colorectal cancer, according to the age, sex and stage of the cancer in Nineveh. Method: This was a retrospective study, conducted among patients at the Mosul Cancer Registry center. Chi-square test for independence was used to study the relationship between age groups, sex and stage of extension variables and some results. Results: about half of people (50.3%) die, is of 55-69 year of age, there good association of age and stage variables with the case fatality rates of cancer, with a p value ≤ 0.05, the result is significant, except for sex. Conclusions: The result of this study indicates that the case fatality rate of patients with colorectal cancer in Nineveh was between developed and developing countries. The case fatality rate of colorectal cancer in men was not significantly differ than women, older patients had a higher case fatality rate compared to younger patients and the case fatality rate by tumor stage was lesser in the localized stage than other stages of the cancer.

colorectal cancer case fatality rate Mosul cancer registry center

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018 Nov; 68 (6): 394-424.
[2]  Ferlay J, Soerjmataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012 cancer incidence and mortality worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer; 2013.
[3]  World Health Organization. Cancer Incidence in Five Continents. Lyon: The World Health Organization and The International Agency for Research on Cancer; 2002.
[4]  World Cancer Research Fund and American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. Washington, DC: American Institute for Cancer Research; 2007.
[5]  Boyle P, Ferlay J. Mortality and survival in breast and colorectal cancer. Nat Clin Pract Oncol 2005; 2 (9): 424-425.
[6]  Parkin D, Bray F, Ferlay J. Global cancer statistics, 2002. CA Cancer J Clin 2006; 55: 74-108.
[7]  Iraqi Ministry of Health. Department of vital statistics 2008 report.
[8]  Coleman MP, Forman D, et al: Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995-2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data. Lancet 2011, 377 (9760): 127-138.
[9]  World Health Organization. International statistical classification of diseases and related health problems. World Health Organization; 2004. 200.
[10]  Young J Jr, Roffers S, Ries L, Fritz A, Hurlbut A: SEER Summary Staging Manual - 2000: Codes and Coding Instructions. Bethesda, MD: National Cancer Institute; 2001.
[11]  Greene FL, Page DL, Fleming ID, Fritz AG, Balch CM, Haller DG, et al. AJCC cancer staging manual. 6th ed. New York: Springer; 2002.
[12]  International agency for research on cancer. ―World cancer fact sheet UK 2012. World Health Organization. www. Cancer, 2014.
[13]  Corazziari I, Quinn M, Capocaccia R. Standard cancer patient population for age standardizing survival ratios. EUR J Cancer 2004; 40: 2307-2316.
[14]  Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016; 16: 626-638.
[15]  Ryabko BY, Stognienko VS, Shokin YI. A new test for randomness and its application to some cryptographic problems. Journal of statistical planning and inference. 2004 Jul 1; 123 (2): 365-76.
[16]  Yu XQ, Baade PD, O’Connell DL. Conditional survival of cancer patients: an Australian perspective. BMC cancer. 2012 Dec; 12 (1): 460.
[17]  O’Connell JB, Maggard MA, Liu JH, et al. Rates of colon and rectal cancers are increasing in young adults. Am Surg 2003; 2003(69): 866-872.
[18]  O’Connell JB, Maggard MA, Livingston EH, Yo CK. Colorectal cancer in the young. Am J Surg 2004; 187(3): 343-348.
[19]  Fairley TL, Cardinez CJ, Martin J, et al. Colorectal cancer in U.S. adults younger than 50 years of age, 1998-2001. Cancer 2006; 107(5, Suppl): 1153-1161.
[20]  Bailey, C.E.; Hu, C.Y.; You, N.; Bednarski, B.K.; Rodriguez-Bigas, M.A.; Skibber, J.M.; Cantor, S.B.; Chang, G.J. Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010. JAMA Surg. 2015, 150, 17-22.
[21]  May, F.P.; Glenn, B.A.; Crespi, C.M.; Ponce, N.; Spiegel, B.M.R.; Bastani, R. Decreasing Black-White Disparities in Colorectal Cancer Incidence and Stage at Presentation in the United States. Cancer Epidemiol. Biomark. Prev. 2017, 26, 762-768.
[22]  Siegel, R.L.; Fedewa, S.A.; Anderson, W.F.; Miller, K.D.; Ma, J.M.; Rosenberg, P.S.; Jemal, A. Colorectal cancer incidence patterns in the United States, 1974-2013. J. Natl. Cancer Inst. 2017, 109.