Prevalence of Hypertension in Glaucoma Patients Attending Eye Clinics in Two Teaching Hospitals in Enugu State Nigeria: A Descriptive Cross-Sectional Study

Alpha Madu^1, , Omumuawuike Ebi², Emmanuel Ihekweazu³ and Valerie Chizelum Okosi⁴

¹Department of Medicine, Kettering General Hospital NHS Foundation Trust, United Kingdom

²Department of Internal Medicine, University of Uyo Teaching Hospital, Akwa Ibom State, Nigeria

³Clinical Services Department, Planned Parenthood of Southern New England, New Haven, United States of America

⁴Department of Pediatrics, University of Nigeria Teaching Hospital, Enugu State, Nigeria

Cite this paper:
Alpha Madu, Omumuawuike Ebi, Emmanuel Ihekweazu and Valerie Chizelum Okosi. Prevalence of Hypertension in Glaucoma Patients Attending Eye Clinics in Two Teaching Hospitals in Enugu State Nigeria: A Descriptive Cross-Sectional Study. American Journal of Medicine Studies. 2020; 8(1):1-5. doi: 10.12691/ajms-8-1-1

Abstract

Background: Glaucoma and hypertension are chronic debilitating illnesses with serious complications. Glaucoma is the commonest cause of irreversible blindness worldwide while hypertension is the commonest cause of cardiovascular-related morbidity and mortality including sudden death. Very few papers have studied the association between these diseases in Nigeria. None of them however has been conducted in the South-Eastern part of the country. Objectives: The aim of this paper was to study the prevalence of hypertension in Glaucoma patients attending eye clinics in two tertiary hospitals in Enugu state, South-East Nigeria. Methods: A cross-sectional survey was conducted among glaucoma patients attending follow-up eye-clinics in two tertiary hospitals in Enugu state, Nigeria over a one-month period. Their blood pressures were measured using an automated blood pressure machine. Hypertension was defined as blood pressure greater than or equal to 140/90mmHg according to the British Hypertension Society classification of Hypertension. Results: 254 patients participated in the survey; 124 were males and 130 were females. Most participants, 91.7%, were aged 41 and above. More than three-quarters were educated up to at least primary school level. The prevalence of hypertension among the participants was 54.8%. Conclusion: We have described a simple prevalence of hypertension in glaucoma patients where slightly above half of the respondents were found to have elevated blood pressures at the time of questioning. Other studies have demonstrated a positive association between hypertension and glaucoma.

Keywords:
prevalence hypertension glaucoma blood pressure blindness Nigeria

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References:

[1]	Kyari, F., Abdull, M.M., Bastawrous, A., Gilbert, C.E. and Faal, H. "Epidemiology of Glaucoma in Sub-Saharan Africa: Prevalence, Incidence and Risk Factors," Middle East Afr J Ophthalmol, 20 (2). 111-125. Apr.2013.
[2]	Budenz, D.L., Barton, K., Whiteside-de Vos, J., et al. "Prevalence of Glaucoma in an Urban West African Population: The Tema Eye Survey," JAMA Ophthalmol, 131(5). 651-658. Mar.2013.
[3]	Malvankar-Mehta, M.S., Feng, L. and Hutnik, C.M.L. "North American cost analysis of brand name versus generic drugs for the treatment of glaucoma," Clinicoecon Outcomes Res., 11. 789-798. Dec.2019.
[4]	Kyari, F., Entekume, G., Rabiu, M., Spry, P., Wormald, R., Nolan, W., et al. "A Population-based survey of the prevalence and types of glaucoma in Nigeria: results from the Nigeria National Blindness and Visual Impairment Survey," BMC Ophthalmol., 15. 176. Dec.2015.
[5]	Sarki, A.M., Nduka, C.U., Stranges, S., Kandala, N., and Uthman, O. "Prevalence of Hypertension in Low- and Middle-Income Countries: A Systematic Review and Meta Analysis," Medicine (Baltimore), 94 (50). e1959. Dec.2015.
[6]	Adeloye, D. and Basquill, C. "Estimating the Prevalence and Awareness Rates of Hypertension in Africa: A Systematic Analysis," PLoS One, 9 (8). e104300. Aug.2014.
[7]	Ezejimofor, M., Uthman, O., Chen, Y., Ezejimofor, B., Ezeabasili, A., Stranges, S. and Kandala, N. "Magnitude and pattern of hypertension in the Niger Delta: a systematic review and meta-analysis of community-based studies," J Glob Health, 8 (1). 010420. Jun.2018.
[8]	Ogah, O.S., Arije, A., Xia, X., Beaney, T., Adebiyi, A., Sani, M.U., et al. "May Measurement Month 2017: screening for hypertension in Nigeria—Sub-Saharan Africa," European Heart Journal Supplements, 21. D86-D88. Apr.2019.
[9]	van Koeverden, A.K., He, Z., Nguyen, C.T.O., Vingrys, A.J., and Bui, B.V. "Systemic hypertension is not protective against chronic intraocular pressure elevation in a rodent model," Sci Rep, 8. 7101. May. 2018.
[10]	Onakoya, A., Ajuluchukwu, J. and Alimi, H. "Primary Open Angle Glaucoma And Intraocular Pressure In Patients With Systemic Hypertension," East African Medical Journal, 86 (2). 74-78. 2009.
[11]	Kyari, F., Abdull, M.M., Wormald, R., Evans, J.R., Nolan, W., Murthy, G.V.S., et al. "Risk factors for open-angle glaucoma in Nigeria: results from the Nigeria National Blindness and Visual Impairment Survey," BMC Ophthalmol., 16. 78. Jun.2016.
[12]	Ministry of Information, Enugu State. About Enugu state. 2019 [cited 2020 09/02/2020]; Available from: https://www.enugustate.gov.ng/index.php/elements-devices/.
[13]	McMonnies, C.W., "Glaucoma history and risk factors," J Optom., 10 (2). 71-78. Mar.2016.
[14]	Raji, Y.R., Abiona, T. and Gureje, O. "Awareness of hypertension and its impact on blood pressure control among elderly nigerians: report from the Ibadan study of aging," Pan Afr Med J., 13 (27). 190. Jul.2017.
[15]	Chijioke, C., Anakwue, R., Okolo, T., Ekwe, E., Eze, C., Agunyenwa, C., et al. "Awareness, Treatment, and Control of Hypertension in Primary Health Care and Secondary Referral Medical Outpatient Clinic Settings at Enugu, Southeast Nigeria," Int J Hypertens, 2016. 5628453. Dec.2016.
[16]	Langman, M.J.S., Lancashire, R.J., Cheng, K.K. and Stewart, P.M. "Systemic hypertension and glaucoma: mechanisms in common and co-occurrence," Br J Ophthalmol., 89 (8). 960- 963. Aug.2005.
[17]	Bae, H.W., Lee, N., Lee, H.S., Seong, G.J. and Kim, C.Y. "Systemic Hypertension as a Risk Factor for Open-Angle Glaucoma: A Meta-Analysis of Population-Based Studies," PLoS One, 9 (9). e108226. Sept.2014.
[18]	Rim, T.H., Lee, S.Y., Kim, S.H., Kim, S.S. and Kim, C.Y. "Increased incidence of open-angle glaucoma among hypertensive patients: an 11-year nationwide retrospective cohort study," J Hypertens, 35 (4). 729-736. Apr. 2017.