Identification of Newer Antimicrobial Agents: A Study of Invitro Antibacterial and Antifungal Activities of Leaf extracts of Medicinal Plant Aerva lanata (L.) Juss. ex Schult

Madhusudhan Kairamkonda¹, Vikram Godishala² and Venkataramana Kandi^3,

¹Department of Biology, Rajiv Gandhi University of Knowledge Technologies, Basar, Telangana, India

²Department of Biotechnology, Vaagdevi Degree and PG College, Warangal, Telangana India

³Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India

Cite this paper:
Madhusudhan Kairamkonda, Vikram Godishala and Venkataramana Kandi. Identification of Newer Antimicrobial Agents: A Study of Invitro Antibacterial and Antifungal Activities of Leaf extracts of Medicinal Plant Aerva lanata (L.) Juss. ex Schult. American Journal of Microbiological Research. 2017; 5(3):66-70. doi: 10.12691/ajmr-5-3-3

Abstract

In the era of presence and spread of infectious diseases caused by microorganisms demonstrating resistance against most antimicrobial agents routinely used in the treatment, there is a serious need of search for potential agents which can be used as antimicrobials. The plant extracts of Aerva lanata were collected and processed using standard procedures. Whatman filter papers were then impregnated with varied concentrations of plant extract and antimicrobial susceptibility testing was performed using Kirby-Bauer disk diffusion method for bacteria. The standard disk diffusion method was used to test antifungal drugs against yeasts, and non-dermatophyte filamentous fungal isolates.The ethanolic extract at a concentration of 600 µg/ mL and 900 µg/ mL showed increased antibacterial activities against Esherichia coli as compared to the standard drug tested at similar concentrations. The chloroform extracts and the ethanol extract revealed increased antibacterial activity against Klebsiella pneumoniae. The chloroform solvent extract showed similar antifungal activities as the standard drug against Candida albicans, and the H₂O extract showed greater antifungal activity against Drechslera halodes as compared to the control drug tested. Antibacterial and antifungal properties of leaf extracts of Aerva lanata plant in comparison with the control drugs revealed either similar or increased activities signifying their potential for future candidates as antimicrobial agents.

Keywords:
Aerva lanata Infectious diseases Antibacterial and antifungal properties of Aerva lanata Antimicrobial resistance

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