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American Journal of Microbiological Research. 2020, 8(2), 57-62
DOI: 10.12691/ajmr-8-2-3
Open AccessReview Article

A Review on Coronavirus Disease (COVID-19) Epidemic Threat for Global Health in 2020

Ahasan Ullah Khan1, Arnika Afrin Proma2, Margia Akter3, Md. Matiur Rahaman4 and Shobhan Das5,

1Faculty of Agriculture, Sylhet Agricultural University, Sylhet 3100, Bangladesh

2Sylhet MAG Osmani Medical College Hospital, Sylhet 3100, Bangladesh

3Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh

4Department of Analysis and Design of Social Protection System, Bonn-Rhein-Sieg University of Applied Sciences, Germany

5Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh

Pub. Date: May 11, 2020

Cite this paper:
Ahasan Ullah Khan, Arnika Afrin Proma, Margia Akter, Md. Matiur Rahaman and Shobhan Das. A Review on Coronavirus Disease (COVID-19) Epidemic Threat for Global Health in 2020. American Journal of Microbiological Research. 2020; 8(2):57-62. doi: 10.12691/ajmr-8-2-3


The viral diseases are a malign condition in the world from 2001 to 2020. The human novel coronavirus disease (COVID-19) was an initial identification in Wuhan, China in December 2019. The major objective is to critically review the present situation of coronavirus in the world. Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) in 2001, Middle East Respiratory Syndrome coronavirus (MERS-CoV) in 2012 and the COVID-19 in 2019 had serious effects in human life in China, Saudi Arabia, and China, respectively. The COVID-19 is a highly mutated virus for the human population in 2020. This review study reveals the host of the virus, history, characteristics, preventive measure, treatment, effects and the epidemic situation in the world.

COVID-19 history epidemic control treatment

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[1]  Woo, P.C., Huang, Y. Lau, S.K., and Yuen, K.Y. 2010. Coronavirus genomics and bioinformatics analysis. Viruses. 2, 1804-1820.
[2]  Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., and Song, J. 2020. A Novel Coronavirus from Patients with Pneumonia in China, 2019. New England Journal of Medicine.
[3]  Lu, R., Zhao, X., Li, J., Niu, P., Yang, B., and Wu, H. 2020. Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet [Internet]. 2020 Jan 30 [cited 2020 Feb 8];0(0). Available from:
[4]  Zhou, P., Yang, X-L., and Wang, X-G. 2020. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin. bioRxiv. 2020.01.22.914952.
[5]  Zhou, P., Yang, X-L., Wang, X-G., Hu, B., Zhang, L., and Zhang, W. 2020. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 1-4.
[6]  SDM, 2020. Seven days in medicine: 8-14 Jan 2020. BMJ. 368:m132.31948945.
[7]  WHO (World Health Organization), final summary SARS, 15 August 2003. Summary table of SARS cases by country, 1 November 2002 - 7 August 2003. Geneva. Available from:
[8]  ICL (Imperial College London). 2020. Report 2: estimating the potential total number of novel coronavirus cases in Wuhan City, China. Jan 2020. Available from:
[9]  WHO (World Health Organization) on 12 February, 2020. 2019-nCoV Situation Report-22.
[10]  Zhang, J., Wang, S., and Xue, Y. 2019. Fecal specimen diagnosis 2019 Novel Coronavirus-Infected Pneumonia. Journal of Medical Virology, 0-2.
[11]  Woo, P.C.; Lau, S.K.; Lam, C.S.; Lau, C.C.; Tsang, A.K.; Lau, J.H.; Bai, R.; Teng, J.L.; Tsang, C.C. and Wang, M. 2012. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J. Virol. 2012, 86, 3995-4008. (In English).
[12]  Lim, Yvonne Xinyi, Yan Ling Ng, James P Tam, and Ding Xiang Liu. 2016. “Human Coronaviruses: A Review of Virus – Host Interactions.”
[13]  Zhou, P.; Fan, H.; Lan, T.; Yang, X.L.; Shi, W.F.; Zhang, W.; Zhu, Y.; Zhang, Y.W.; Xie, Q.M.; Mani, S.; et al. Fatal swine acute diarrhea syndrome caused by an HKU2-related coronavirus of bat origin. Nature 2018, 556, 255-258. (In English).
[14]  Su, S.; Wong, G.; Shi, W.; Liu, J.; Lai, A.C.K.; Zhou, J.; Liu, W.; Bi, Y.; Gao, G.F. Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses. Trends Microbiol. 2016, 24, 490-502. (In English).
[15]  Forni, D.; Cagliani, R.; Clerici, M.; Sironi, M. Molecular Evolution of Human Coronavirus Genomes. Trends Microbiol. 2017, 25, 35-48. (In English).
[16]  De Groot, R.J., Baker, S.C., Baric, R.S., Brown, C.S., Drosten, C., and Enjuanes, L. 2013. Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group. J Virol. 87: 7790-7792.
[17]  Jaffar, A., Al-Tawfiq, M.D., FACP, Abdullah, Assiri, M.D., FACP, Ziad A., Memish, M.D., FACP. 2013. Middle East respiratory syndrome novel corona (MERS-CoV) infection Epidemiology and outcome update. Saudi Med J. Vol. 34 (10).
[18]  Zaki, A.M., van Boheemen, S., Bestebroer, T.M., Osterhaus, A.D.M.E., and Fouchier, R.A.M. 2012. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med. 367: 1814-1820.
[19]  Assiri, A., Al-Tawfiq, J.A., Al-Rabeeah, A.A., Al-Rabiah, F.A., Al-Hajjar, S. and Al-Barrak, A. 2013. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis. 13: 752-761.
[20]  Assiri, A., McGeer, A., Perl, T.M., Price, C.S., Al Rabeeah, A.A., and Cummings, D.A. 2013. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med. 369:407-416.
[21]  Memish, Z.A., Zumla, A.I., Al-Hakeem, R.F., Al-Rabeeah, A.A. and Stephens, G.M. 2013. Family cluster of Middle East respiratory syndrome coronavirus infections. N Engl J Med 2013; 368:2487-2494.
[22]  Al-Ahdal, M.N., Al-Qahtani, A.A., and Rubino, S. 2012. Coronavirus respiratory illness in Saudi Arabia. J Infect DevCtries. 6: 692-694.
[23]  CDC, (Centers for Disease Control and Prevention). 2012. Severe respiratory illness associated with a novel coronavirus-Saudi Arabia and Qatar, 2012. MMWR Morb Mortal Wkly Rep. 61: 820.
[24]  Hijawi, B., Abdallat, M., Sayaydeh, A., Alqasrawi, S., and Haddadin, A. 2013. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J. 19 Suppl 1: S12-S8.
[25]  ECDC, (European Centre for Disease Prevention and Control). 2013. Severe respiratory disease of unknown origin-Jordan-outbreak in ICU. Communicable Disease Threats Report. (Updated 2012 April-May 29; Cited 2013 May 22). Available from:
[26]  HPA, (Health Protection Agency), UK Novel Coronavirus Investigation team. 2013. Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013. Euro Surveill. 18: 20427.
[27]  Bermingham, A., Chand, M.A., Brown, C.S., Aarons, E., Tong, C. and Langrish, C. 2012. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012. Euro Surveill. 17: 20290.
[28]  Buchholz, U., Müller, M.A., Nitsche, A., Sanewski, A., Wevering, N. and Bauer-Balci, T. 2013. Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012. Euro Surveill. 18: 20406.
[29]  Mailles, A., Blanckaert, K., Chaud, P., van der Werf, S., Lina, B. and Caro, V. 2013. First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013. Euro Surveill. 18. pii: 20502.
[30]  WHO, (World Health Organization). Novel coronavirus infection. (Update 2013 May 22; Accessed 2013 August 5. Available from URL:
[31]  Drosten, C., Seilmaier, M., Corman, V.M., Hartmann, W., Scheible, G. and Sack, S. 2013. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis. 13: 745-751.
[32]  ISID (International Society for Infectious Diseases). 2013. MERS-COV- Eastern Mediterranean (16): Italy Ex Jordan, Contact Cases, WHO. ProMed mail. (Update 2008; Accessed 2013 August 5). Available from URL: promedprint.php?id=1750425.
[33]  Khot, W.Y. and Nadkar, M.Y. 2020.The 2019 Novel Coronavirus Outbreak - A Global Threat, 68(March), pp. 67-71.
[34]  Ashour, Hossam M., Walid F. Elkhatib, Masudur Rahman, and Hatem A. Elshabrawy. 2020. Insights into the Recent 2019 Novel Coronavirus ( SARS - CoV - 2 ) in Light of Past Human Coronavirus Outbreaks. (Figure 1): 1-15.
[35]  China CDC 2020. Tracking the Epidemic. Available form: http://
[36]  Dente, S.M.R. 2020. Corona virus (COVID-19) epidemic A stock-flow perspective. (February).
[37]  Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y. 2020. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med. NEJMoa2001316.
[38]  Wu, J.T., Leung, K., Leung, G.M. 2020. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study. Lancet. S0140-6736(20)30260-9.
[39]  JHI (John Hopkins Institution). 2020. Coronavirus COVID-19 Global cases. Available from: 7b48e9ecf6.
[40]  Dong, E., Du, H. and Gardner L. 2020. An interactive web-based dashboard to track COVID-19 in real time. The Lancet infectious diseases.
[41]  Wu, P., Hao, X., Lau, E.H.Y., Wong, J.Y., Leung, K.S.M., Wu, J.T. 2020. Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020.Euro Surveill. 25(3): 25.
[42]  Backer, J.A., Klinkenberg, D., Wallinga, J. 2020. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. Euro Surveill. 25(5): 2000062 10.2807/1560-7917.ES.2020.25.5.2000062.
[43]  Swift, R. Sixty more people confirmed with coronavirus on cruise ship in Japan: media. Tokyo: Reuters. [Accessed 10 Feb 2020]. Available from: japan/sixty-more-people-confirmed-with-coronavirus-on-cruise- ship-in-japan-media-idUSKBN2040FG.