American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2018, 6(2), 26-29
DOI: 10.12691/ajmcr-6-2-4
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Invasive Ductal Carcinoma of the Breast with Medullary Features or Medullary Carcinoma of the Breast: A Challenging Histopathological Case Report with Review of Literature

Mazaher Ramezani1, Shima Jalalvandi1, Fatemeh Rezaali1 and Masoud Sadeghi2,

1Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

2Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Pub. Date: March 30, 2018

Cite this paper:
Mazaher Ramezani, Shima Jalalvandi, Fatemeh Rezaali and Masoud Sadeghi. Invasive Ductal Carcinoma of the Breast with Medullary Features or Medullary Carcinoma of the Breast: A Challenging Histopathological Case Report with Review of Literature. American Journal of Medical Case Reports. 2018; 6(2):26-29. doi: 10.12691/ajmcr-6-2-4


Medullary Breast carcinoma (MBC) is an infrequent type of breast cancer and is in the differential diagnosis of invasive ductal carcinoma (IDC) with medullary features. We reported a 35-year-old lady with left breast since 6 months ago. CEA tumor marker serum level and CA15-3 were within normal limits. The patient underwent the incomplete left mastectomy. Gross specimen revealed gray-yellow hemorrhagic tumor lesion with pushing border. Histopathology demonstrated highly atypical cells with lymphocytic infiltration and mainly pushing border but with infiltrative margin in few areas. The permanent diagnosis was “invasive ductal carcinoma with medullary features“. We conclude that careful histopathological evaluation and considering strict criteria is necessary for definitive diagnosis and subsequent proper treatment.

invasive ductal carcinoma medullary carcinoma breast cancer case report

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