Invasive Ductal Carcinoma of the Breast with Medullary Features or Medullary Carcinoma of the Breast: A Challenging Histopathological Case Report with Review of Literature

Mazaher Ramezani¹, Shima Jalalvandi¹, Fatemeh Rezaali¹ and Masoud Sadeghi^2,

¹Molecular Pathology Research Center, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

²Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

Cite this paper:
Mazaher Ramezani, Shima Jalalvandi, Fatemeh Rezaali and Masoud Sadeghi. Invasive Ductal Carcinoma of the Breast with Medullary Features or Medullary Carcinoma of the Breast: A Challenging Histopathological Case Report with Review of Literature. American Journal of Medical Case Reports. 2018; 6(2):26-29. doi: 10.12691/ajmcr-6-2-4

Abstract

Medullary Breast carcinoma (MBC) is an infrequent type of breast cancer and is in the differential diagnosis of invasive ductal carcinoma (IDC) with medullary features. We reported a 35-year-old lady with left breast since 6 months ago. CEA tumor marker serum level and CA15-3 were within normal limits. The patient underwent the incomplete left mastectomy. Gross specimen revealed gray-yellow hemorrhagic tumor lesion with pushing border. Histopathology demonstrated highly atypical cells with lymphocytic infiltration and mainly pushing border but with infiltrative margin in few areas. The permanent diagnosis was “invasive ductal carcinoma with medullary features“. We conclude that careful histopathological evaluation and considering strict criteria is necessary for definitive diagnosis and subsequent proper treatment.

Keywords:
invasive ductal carcinoma medullary carcinoma breast cancer case report

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