American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Apply for this position
Open Access
Journal Browser
Go
American Journal of Medical Case Reports. 2017, 5(10), 256-258
DOI: 10.12691/ajmcr-5-10-1
Open AccessCase Report

Non Compaction Cardiomyopathy Masquerading as Asthma: A Case Report

Bodar VH1, , Upadhyay A1, Singh S1, Ullah T1, Colasacco JA2 and Pinsker R1

1Department of Internal Medicine, Jamaica Hospital Medical Center, Jamaica, NY 11418, USA

2Department of Cardiology, Jamaica Hospital Medical Center, Jamaica, NY 11418, USA

Pub. Date: October 14, 2017

Cite this paper:
Bodar VH, Upadhyay A, Singh S, Ullah T, Colasacco JA and Pinsker R. Non Compaction Cardiomyopathy Masquerading as Asthma: A Case Report. American Journal of Medical Case Reports. 2017; 5(10):256-258. doi: 10.12691/ajmcr-5-10-1

Abstract

Left ventricular non-compaction (LVNC) is a rare form of cardiomyopathy, which leads to progressive heart failure, arrhythmias, and thromboembolic events. Due to variable clinical presentations, it is often misdiagnosed as another cardiomyopathy or asthma. Here we report a case of 50 year-old-male who had multiple emergency room visits for shortness of breath (SOB) which were treated acutely with bronchodilators for presumptive asthma exacerbations. Subsequently, a 2D, color flow transthoracic echocardiogram was performed, which revealed the presence of dilated cardiomyopathy, and a low LV ejection fraction. In addition, left ventricular trabeculation was greater than that anticipated, with prominent inter trabecular recesses, supporting the diagnosis of LVNC. A family history of early onset heart failure was present. This case is presented to help physicians consider non-compaction cardiomyopathy as an etiology in patients who present with SOB and low ejection fraction (EF).

Keywords:
cardiomyopathy non-compaction dyspnea SOB

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References:

[1]  Bhat T, Lafferty J, Teli S, Rjaili GA, Olkovsky Y, Costantino T. Isolated. Left Ventricular Noncompaction Cardiomyopathy diagnosed by Transesophageal Echocardiography. Clinical Medicine Insights Cardiology. 2011; 5: 23-27.
 
[2]  Hussein A, Karimianpour A, Collier P, Krasuski RA. Isolated Noncompaction of the Left Ventricle in Adults. J Am Coll Cardiol. 2015 Aug 4; 66(5): 578-85.
 
[3]  Steger CM.Left ventricular non-compaction. BMJ Case Rep. 2014 Jun 24; 2014.
 
[4]  Vatta M, Mohapatra B, Jimenez S, Sanchez X, Faulkner G, Perles Z, Sinagra G, Lin JH, Vu TM, Zhou Q, Bowles KR, Di Lenarda A, Schimmenti L, Fox M, Chrisco MA, Murphy RT, McKenna W, Elliott P, Bowles NE, Chen J, Valle G, Towbin JA. Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. J Am Coll Cardiol. 2003 Dec 3; 42(11): 2014-27.
 
[5]  Kovacevic-Preradovic T, Jenni R, Oechslin EN, Noll G, Seifert B, Attenhofer Jost CH. Isolated left ventricular noncompaction as a cause for heart failure and heart transplantation: a single center experience. Cardiology. 2009; 112(2): 158-64.
 
[6]  Haland TF, Saberniak J, Leren IS, Edvardsen T, Haugaa KH.Echocardiographic comparison between left ventricular non-compaction and hypertrophic cardiomyopathy. International Journal of Cardiology.2017 Feb 1; 228: 900-905.
 
[7]  Ikeda U., Minamisawa M., Koyama J. Isolated left ventricular non-compaction cardiomyopathy in adults. Journal of Cardiology. 2015, 65 2: 91-97.
 
[8]  Jenni R, Oechslin E, Schneider J, Attenhofer Jost C, Kaufmann PA. Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy. Heart. 2001; 86(6): 666-71.
 
[9]  Ross T. Murphy, Rajesh Thaman, Juan Gimeno Blanes, Deirdre Ward, Elias Sevdalis, Efi Papra, Anatoli Kiotsekolglou, Maria T. Tome, Denis Pellerin, William J. McKenna, Perry M. Elliott. Natural history and familial characteristics of isolated left ventricular non-compaction. Eur Heart J. 2005; 26(2): 187-192.
 
[10]  Ashrith G, Gupta D, Hanmer J, Weiss RM. Cardiovascular magnetic resonance characterization of left ventricular non-compaction provides independent prognostic information in patients with incident heart failure or suspected cardiomyopathy. Journal of Cardiovascular Magnetic Resonance. 2014; 16(1): 64.
 
[11]  Goud A, Padmanabhan S. A rare form of cardiomyopathy: left ventricular non-compaction cardiomyopathy. Journal of Community Hospital Internal Medicine Perspectives. 2016; 6(1):10.3402/jchimp.v6.29888.
 
[12]  Shemisa K, Li J, Tam M, Barcena J. Left ventricular noncompaction cardiomyopathy. Cardiovasc Diagn Ther. 2013 Sep; 3(3): 170-175.
 
[13]  Stöllberger C, Finsterer J. Thrombi in left ventricular hypertrabeculation/noncompaction--review of the literature. Acta Cardiol. 2004 Jun; 59(3):341-4. Review.
 
[14]  Stanton C., Bruce C., Connolly H., Brady P., Syed I., Hodge D., Asirvatham S., Friedman P. Isolated Left Ventricular Noncompaction Syndrome. American Journal of Cardiology. 2009; 104: 8: 1135-1138.
 
[15]  Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA 3rd, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO, Smith SC Jr, Jacobs AK, Adams, CD, Anderson JL, Buller CE, Creager MA, Ettinger SM, Faxon DP, Halperin JL, Hiratzka LF, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Ornato JP, Page RL, Riegel B, Tarkington LG, Yancy CW; American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing) Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices).; American Association for Thoracic Surgery.; Society of Thoracic Surgeons. ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation
 
[16]  Chinushi M, Iijima K, Furushima H, Izumi D, Sato A, Yagihara N, Hasegawa K, Watanabe H, Soejima K, Aizawa Y. Suppression of storms of ventricular tachycardia by epicardial ablation of isolated delayed potential in noncompaction, cardiomyopathy. Pacing Clin Electrophysiol. 2013 Apr; 36(4):e115-9.
 
[17]  Ackerman, M.J., Priori, S.G., Willems, S. et al, HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies. Europace. 2011; 13:1077-1109.