American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2017, 5(7), 187-189
DOI: 10.12691/ajmcr-5-7-5
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Visceral Leishmaniasis with Secondary Hemophagocytosis in a Sickle Cell Anemia Patient

Dhayhi Nabil S.1, , Arishi Haider M.1, Alnami Mohammed Y.1 and Dammur Prabhara1

1King Fahad Central Hospital, Jizan, Saudi Arabia

Pub. Date: August 07, 2017

Cite this paper:
Dhayhi Nabil S., Arishi Haider M., Alnami Mohammed Y. and Dammur Prabhara. Visceral Leishmaniasis with Secondary Hemophagocytosis in a Sickle Cell Anemia Patient. American Journal of Medical Case Reports. 2017; 5(7):187-189. doi: 10.12691/ajmcr-5-7-5


Sickle cell anemia (SCA ) is one of the most common hemoglobinopathies, which is characterized by a high level of abnormal hemoglobin called hemoglobin S (Hb S). This abnormal hemoglobin results from changes in amino acids and valine instead of glutamine at the sixth position of the β globin molecule. Two affected genes are needed to develop sickle cell anemia, homozygous Hb S.

sickle cell anemia

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[1]  Sodipo JO, Padgett D, Warrie E, and Olopoenia L. Parasitic infections in sickle cell crisis: Nigerian experience; Journal of the National Medical Association 89, no. 4 (1997Apr):285-288.
[2]  Makani J, Williams TN, Marsh K. Sickle cell disease in Africa: Burden and research priorities. Ann Trop Med Parasitol. 2007; 101: 3-14. [PubMed]
[3]  Al-Qurashi MM, El-Mouzan MI, Al-Herbish AS, Al-Salloum AA, Al-Omar AA. The prevalence of sickle cell disease in Saudi children and adolescents. A community-based survey. Saudi Med J.2008; 29: 1480-3.[PubMed]
[4]  Alvar J, Croft S, Olliaro P. Chemotherapy in the treatment and control of leishmaniasis. Adv Parasitol 2006; 61: 223.
[5]  Bern C, Adler-Moore J, Berenguer J, et al. Liposomal amphotericin B for the treatmentof visceral leishmaniasis. Clin Infect Dis 2006; 43: 917.
[6]  Daniel Garcerant,* Luisa Rubiano, Victor Blanco, Javier Martinez, Nancy C. Baker, and Noah Craft. Possible Links between Sickle Cell Crisis and Pentavalent Antimony.