American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2016, 4(12), 376-377
DOI: 10.12691/ajmcr-4-12-2
Open AccessCase Report

Seller Mass in a Young Man with Diabetes Insipidus and Panhypopituitarism—What is the Diagnosis?

Smita Subramaniam1, , Bassam Ghabach1 and Andrey Manov1

1Department of Internal Medicine, JPS Hospital [John Peter Smith], Fort Worth, Texas USA

Pub. Date: December 23, 2016

Cite this paper:
Smita Subramaniam, Bassam Ghabach and Andrey Manov. Seller Mass in a Young Man with Diabetes Insipidus and Panhypopituitarism—What is the Diagnosis?. American Journal of Medical Case Reports. 2016; 4(12):376-377. doi: 10.12691/ajmcr-4-12-2


Pituitary and suprasellar lesions can cause diabetes insipidus due to interruption of pathways carrying vasopressin and oxytocin to pituitary. Central diabetes insipidus is characterized by polyuria and polydipsia and is a direct result of deficiency of vasopressin. Midline mass lesions in brain and body warrant further workup for possible diagnosis of germ cell tumors. We present an interesting case of a young man with suprasellar brain lesion and diabetes insipidus with pan hypopituitarism where further workup revealed germinoma. Patient had a favorable outcome with surgery followed by radiation therapy.

diabetes insipidus germ cell tumor panhypopituitarism

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