American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2016, 4(12), 376-377
DOI: 10.12691/ajmcr-4-12-2
Open AccessCase Report

Seller Mass in a Young Man with Diabetes Insipidus and Panhypopituitarism—What is the Diagnosis?

Smita Subramaniam1, , Bassam Ghabach1 and Andrey Manov1

1Department of Internal Medicine, JPS Hospital [John Peter Smith], Fort Worth, Texas USA

Pub. Date: December 23, 2016

Cite this paper:
Smita Subramaniam, Bassam Ghabach and Andrey Manov. Seller Mass in a Young Man with Diabetes Insipidus and Panhypopituitarism—What is the Diagnosis?. American Journal of Medical Case Reports. 2016; 4(12):376-377. doi: 10.12691/ajmcr-4-12-2

Abstract

Pituitary and suprasellar lesions can cause diabetes insipidus due to interruption of pathways carrying vasopressin and oxytocin to pituitary. Central diabetes insipidus is characterized by polyuria and polydipsia and is a direct result of deficiency of vasopressin. Midline mass lesions in brain and body warrant further workup for possible diagnosis of germ cell tumors. We present an interesting case of a young man with suprasellar brain lesion and diabetes insipidus with pan hypopituitarism where further workup revealed germinoma. Patient had a favorable outcome with surgery followed by radiation therapy.

Keywords:
diabetes insipidus germ cell tumor panhypopituitarism

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