American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
American Journal of Medical Case Reports. 2016, 4(7), 228-231
DOI: 10.12691/ajmcr-4-7-2
Open AccessCase Report

Tachyarrhythmias in Microscopic Polyangitis Responding Well to Plasmapharesis Treatment

Hassan Tahir1 and Vistasp Daruwalla2,

1Department on Internal Medicine, Temple University, Conemaugh Memorial Hospiatl, Johnstown PA, USA

2Department of Radiology, Wyne state University, Detroit Medical Center, Detroit Michigan, USA

Pub. Date: July 09, 2016

Cite this paper:
Hassan Tahir and Vistasp Daruwalla. Tachyarrhythmias in Microscopic Polyangitis Responding Well to Plasmapharesis Treatment. American Journal of Medical Case Reports. 2016; 4(7):228-231. doi: 10.12691/ajmcr-4-7-2


Microscopic polyangiitis (MPA) is a form of anti neutrophilic cytoplasmic antibody associated necrotizing vasculitis, which may present with a variety of clinical manifestations. Cardiac involvement in vaculitis is common and the manifestations usually include cardiomyopathy, pericarditis and arrhythmias. Our patient presented with dyspnea, hemoptysis and acute kidney injury. The patient developed frequent episodes of supraventricular tachycardia (SVT) and non-sustained ventricular tachycardia during the course of his stay, which subsequently resolved on treatment with plasmapheresis. Mortality rate is significantly high in patients with pulmonary hemorrhage and renal failure; plasmpheresis has proven to be beneficial in such acute case. Our case not only highlights the therapeutic effects of plasmapheresis on MPA but also stresses the importance of prompt plasmapheresis to mitigate MPA complications like SVT.

microscopic polyangitis plasmapharesis

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Wang CC1, Shiang JC, Tsai MK, Chen IH, Lin SH, Chu P, Wu CC. Prompt plasmapheresis successfully rescue pulmonary-renal syndrome caused by ANCA negative microscopic polyangiitis. Clin Rheumatol. 2009 Dec; 28(12):1457-60.
[2]  De Joode AA1, Sanders JS, Smid WM, Stegeman CA. Plasmapheresis rescue therapy in progressive systemic ANCA-associated vasculitis: single-center results of stepwise escalation of immunosuppression. J Clin Apher. 2014 Oct; 29(5): 266-72.
[3]  Pagnoux C1, Guillevin L. Cardiac involvement in small and medium-sized vessel vasculitides. Lupus. 2005; 14(9): 718-22.
[4]  Kaur P1, Palya A, Hussain H, Dabral S. Microscopic polyangiitis presenting as early cardiac tamponade. J Clin Rheumatol. 2010 Mar; 16(2): 86-7.
[5]  Kim BK1, Park SY, Choi CB, Kim TH, Jun JB, Jang SM, Park MH, Uhm WS. A case of microscopic polyangiitis associated with aortic valve insufficiency. Rheumatol Int. 2013 Apr; 33(4): 1055-8.
[6]  Aydin Z1, Gursu M, Karadag S, Uzun S, Tatli E, Sumnu A, Ozturk S, Kazancioglu R. Role of plasmapheresis performed in hemodialysis units for the treatment of anti-neutrophilic cytoplasmic antibody-associated systemic vasculitides. Ther Apher Dial. 2011 Oct; 15(5): 493-8.