American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2016, 4(5), 180-185
DOI: 10.12691/ajmcr-4-5-10
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Endovascular Treatment of Deep Vein Thrombosis Associated with May-Thurner Syndrome: A Case Series

Teresa Arquero Portero1, José Urbano García2, Aránzazu García Raso1, 3, and Ma Pilar Llamas Sillero1

1Department of Hematology, Thrombosis Unit, Fundacion Jimenez Diaz University Hospital, Madrid, Spain

2Department of Radiology, Vascular and Interventional Radiology Unit, Fundacion Jimenez Diaz University Hospital, Madrid, Spain

3Experimental Hematology Laboratory, Health Research Institute IIS-FJD, Madrid, Spain

Pub. Date: May 31, 2016

Cite this paper:
Teresa Arquero Portero, José Urbano García, Aránzazu García Raso and Ma Pilar Llamas Sillero. Endovascular Treatment of Deep Vein Thrombosis Associated with May-Thurner Syndrome: A Case Series. American Journal of Medical Case Reports. 2016; 4(5):180-185. doi: 10.12691/ajmcr-4-5-10


Introduction: May-Thurner syndrome (MTS) is an entity caused by the compression of the left iliac vein that predispose to acute deep vein thrombosis (DVT) of left lower limb. While standar management is anticoagulant therapy, a review of the literature reveals that new endovascular therapies can offer more optimal outcome than anticoagulation alone, preserving normal venous valve function, and avoiding post-thrombotic syndrome. In addition, we have detected that the highest risk of complications appears when MTS is associated with another congenital or acquired prothrombotic factor (thrombophilia). Case presentation: We report four causes of MTS in caucasian patients treated with endovascular techniques in our hospital over the last years. All patients were middle-aged severe symptomatic women with positive venographic findings for acute or chronic extensive left lower-extremity DVT. In addition, all patients were positive for thrombophilia test. Conclusion: DVT study in patients with MTS must include a search for thrombophilia factors, as those patients are most likely to benefit from new technical approaches.

May-Thurner syndrome iliac vein compression syndrome venous thrombosis endovascular therapy stent post-thrombotic syndrome case report

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