American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2016, 4(3), 108-110
DOI: 10.12691/ajmcr-4-3-9
Open AccessCase Report

Diagnosis of the Combination of Immune Thrombocytopenia and Woodhouse-Sakati Syndrome

Mehmet Dagli1, Ali Kutlucan1, , Kemal Fidan1, Leyla Kutlucan2, Abdulkadir Basturk1 and Suleyman Hilmi Ipekci1

1Department of Internal Medicine, Faculty of Medicine, Selcuk University, Konya, Turkey

2Department of Anesthesiology, Konya Training and Research Hospital, Konya, Turkey

Pub. Date: April 15, 2016

Cite this paper:
Mehmet Dagli, Ali Kutlucan, Kemal Fidan, Leyla Kutlucan, Abdulkadir Basturk and Suleyman Hilmi Ipekci. Diagnosis of the Combination of Immune Thrombocytopenia and Woodhouse-Sakati Syndrome. American Journal of Medical Case Reports. 2016; 4(3):108-110. doi: 10.12691/ajmcr-4-3-9

Abstract

Woodhouse-Sakati Syndrome (WSS) is a rare autosomal recessive syndrome characterized by sensorineural hearing loss, ECG ST-T changes, partial alopecia, hypogonadism, diabetes, and moderate mental retardation. A 23-year-old male patient was admitted to our hospital with complaints of purpura and petechial rashes. His platelet count was 3.04 x 109/L and the peripheral blood smear was compatible with this count. No atypical cell was observed. He had mild mental retardation. He had hearing loss since childhood. Physical examination showed widespread petechiae and purpura on bilateral lower extremities. Significant growth retardation was detected and male pattern hair growth was less. In genital examination, bilateral testicles were small; penis length was 1 cm and it was 4 cm when elongated. T negativity was present in precordial derivations of ECG. He was diagnosed Immune thrombocytopenic purpura (ITP) and WSS according to these findings. In addition to ITP treatment with steroids, the combination of testosterone propionate and testosterone phenyl propionatewas also administered to him. Upon we observed that there was an increase in his platelet number, he was discharged from the hospital. WSS is a very rare disease. Different components of the syndrome have been reported in different patients.It is the first time in the literature that ITP is observedtogether with WSS in a male patient.

Keywords:
woodhouse-sakati syndrome immune thrombocytopenic purpura

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