American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
Go
American Journal of Medical Case Reports. 2016, 4(2), 71-73
DOI: 10.12691/ajmcr-4-2-10
Open AccessCase Report

Reactive Solitary Eccrine Syringofibroadenoma: A Very Rare Adnexal Tumour of Skin

Anup Kumar Tiwary1, , Firdous Jahan1, Dharmendra Kumar Mishra1 and S.S. Chaudhary1

1Department of Dermatology, Venereology and Leprosy, Rajendra Institute of Medical Sciences, Ranchi, India

Pub. Date: March 23, 2016

Cite this paper:
Anup Kumar Tiwary, Firdous Jahan, Dharmendra Kumar Mishra and S.S. Chaudhary. Reactive Solitary Eccrine Syringofibroadenoma: A Very Rare Adnexal Tumour of Skin. American Journal of Medical Case Reports. 2016; 4(2):71-73. doi: 10.12691/ajmcr-4-2-10

Abstract

Eccrine syringofibroadenoma (ESFA) is a very rare benign tumour of intraepidermal part (acrosyringium) of eccrine sweat duct. Based on the evidence of known aetiological factors, two forms have been proposed: reactive ESFA and non-reactive ESFA. Rarely, non-reactive forms have been seen to be associated with ectodermal dysplasia. Reactive type has been considered as hyperplastic or hamartomatous response to many inflammatory and neoplastic dermatoses. Owing to its clinical similarity with other chronic dermatoses like deep mycoses, squamous cell carcinoma, diabetic foot ulcer or leprous neuropathic ulcer, it may remain misdiagnosed. Distinctive histopathological features with or without immunostaining usually confirm the diagnosis. ESFA is a very rare entity as to the best of my knowledge, only around 50 cases have been reported all over the world till date. Herein we report a case of reactive solitary ESFA on the right foot in a 65 years old male.

Keywords:
acrosyringium eccrine syringofibroadenoma ectodermal dysplasia hamartomatous

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

Figures

Figure of 5

References:

[1]  Mascaro JM. Considerations sur les tumeurs fibroepitheliales: Le syringofibroadenome eccrine. Ann Dermatol Syphiligr 1963;90: 1443-53.
 
[2]  Starink TM. Eccrine syringofibroadenoma: Multiple lesions representing a new cutaneous marker of the Schopf syndrome, and solitary nonhereditary tumors. J Am Acad Dermatol 1997; 36: 569-76.
 
[3]  French LE. Reactive eccrine syringofibroadenoma: An emerging subtype. Dermatology 1997; 195:30910.
 
[4]  Singh N, Chandrashekar L, Shakthi P, Thappa DM, Badhe BA, Sylvia MT. Reactive eccrine syringofiroadenomatosis presenting as bilateral plantar hyperkeratosis. Indian J Dermatol 2015; 60:403-5.
 
[5]  Utani A, Yabunami H, Kakuta T, Endo H, Shinkai H. Reactive eccrine syringofibroadenoma: An association with chronic foot ulcer in a patient with diabetes mellitus. J Am Acad Dermatol 1999; 41: 650-1.
 
[6]  Heng YK, Pan JY, Tan SH, Tey HL. Eccrine syringofiroadenomatosis of the reactive subtype occurring in chronic poorly-controlled psoriasis. Indian J Dermatol Venereol Leprol 2014;80:534-6.
 
[7]  Hu S, Bakshandeh H, Kerdel FA, Rongioletti F, Romanelli P. Eccrine syringofibroadenoma of clear cell variant: An immunohistochemical study. Am J Dermatol 2005; 27:228-31.
 
[8]  Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, et al. Wnt signaling and human diseases: What are the therapeutic implications? Lab Invest 2007; 87:97103.
 
[9]  Bjarke T, Ternesten-Bratel A, Hedblad M, Rausing A. Carcinoma and eccrine syringofibroadenoma: A report of five cases. J Cutan Pathol 2003; 30:382-92.
 
[10]  Tey HL. Characterizing the nature of eccrine syringofibroadenoma: Illustration with a case showing spontaneous involution Clin Exp Dermatol 2009;34: e668.