American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2016, 4(1), 16-18
DOI: 10.12691/ajmcr-4-1-5
Open AccessArticle

A Case of Periprocedural Discontinuation of Apixaban Resulting in Intra-aortic Thrombosis

Sabu John1, Pramod Theetha Kariyanna2, , Jonathan Marmur1, Kamal Preet Singh1 and Mary Mallappallil1

1Division of Cardiology, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A.

2Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A.

Pub. Date: January 21, 2016

Cite this paper:
Sabu John, Pramod Theetha Kariyanna, Jonathan Marmur, Kamal Preet Singh and Mary Mallappallil. A Case of Periprocedural Discontinuation of Apixaban Resulting in Intra-aortic Thrombosis. American Journal of Medical Case Reports. 2016; 4(1):16-18. doi: 10.12691/ajmcr-4-1-5


Apixaban, a novel oral anticoagulant is approved for anticoagulation in non-valvular atrial fibrillation. Apixaban is found to be superior to warfarin in prevention of stroke and thromboembolism and is associated with lesser risk of bleeding. Peri-procedural discontinuation of apixaban is safe, but the risk of thrombosis exists. We here present a case of arterial thrombosis that lead to lower limb ischemia upon periprocedural discontinuation of apixaban.

apixaban anticoagulation non-valvular atrial fibrillation thrombosis

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