American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2015, 3(9), 291-296
DOI: 10.12691/ajmcr-3-9-8
Open AccessCase Report

Extra-Ocular Sebaceous Carcinoma of the Skin: A Report of Five Cases and a Review of the Literature

Mariem MOHAMED1, , Lobna BOUSSOFARA2, Abdlefaddeh SLAMA3, Mohamed DENGUEZLI2, Colandane BELAJOUZA2, Bedreddine SRIHA4, Najet GHARIANI2 and Rafiaa NOUIRA2

1Dermatology Department, Fattouma Bourguiba University Hospital, Monastir, Tunisia

2Dermatology Departments, Farhat Hached University Hospital, Sahloul University Hospital, Sousse, Tunisia

3Oral and Maxillo-Facial Surgery Department, Sahloul University Hospital, Sousse, Tunisia

4Pathology Departments, Farhat Hached University Hospital, Sahloul University Hospital, Sousse, Tunisia

Pub. Date: August 24, 2015

Cite this paper:
Mariem MOHAMED, Lobna BOUSSOFARA, Abdlefaddeh SLAMA, Mohamed DENGUEZLI, Colandane BELAJOUZA, Bedreddine SRIHA, Najet GHARIANI and Rafiaa NOUIRA. Extra-Ocular Sebaceous Carcinoma of the Skin: A Report of Five Cases and a Review of the Literature. American Journal of Medical Case Reports. 2015; 3(9):291-296. doi: 10.12691/ajmcr-3-9-8

Abstract

Background: Extra ocular sebaceous carcinoma is a rare aggressive adnexal tumour. The diagnosis of this tumour is difficult due to the variety of its clinical and histopathological features. The prognosis is actually considered as aggressive as the ocular counterpart. Methods and results: We propose to discuss the clinical features, histopathological findings and aggressive potential of extra ocular sebaceous carcinoma. Therefore, five extra ocular sebaceous carcinoma cases, diagnosed at the Dermatology and Pathology departments of Farhat Hached Hospital, from January 1998 to December 2007, were reviewed. The diagnosis was based on a histopathological examination. Three of them developed locoregional and/or distant metastases. One patient died from metastatic disease. Surgery was the mainstay of treatment without any cutaneous recurrence after a mean follow-up of two years. Conclusions: Extra ocular sebaceous carcinoma has an unpredictable prognosis. It can be highly aggressive and cause death. Surgery remains the mainstay of treatment.

Keywords:
sebaceous adenocarcinoma extra ocular sebaceous carcinoma skin cancer prognosis surgery

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