American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2015, 3(8), 265-268
DOI: 10.12691/ajmcr-3-8-11
Open AccessCase Report

Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review

Semra Ayturk1, Mehmet Celik1, , Onur Mert2, Nuray Can3, Atakan Sezer4, Sibel Guldiken1 and Ahmet Muzaffer Demir5

1Department of Internal Medicine, Division of Endocrinology and Metabolism, Trakya Medical School, University of Trakya, Edirne, Turkey

2Department of Internal Medicine, Trakya Medical School, University of Trakya, Edirne, Turkey

3Department of Pathology, Trakya Medical School, University of Trakya, Edirne, Turkey

4Department of General Surgery, Trakya Medical School, University of Trakya, Edirne, Turkey

5Department of Internal Medicine, Division of Hematology, Trakya Medical School, University of Trakya, Edirne, Turkey

Pub. Date: July 21, 2015

Cite this paper:
Semra Ayturk, Mehmet Celik, Onur Mert, Nuray Can, Atakan Sezer, Sibel Guldiken and Ahmet Muzaffer Demir. Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review. American Journal of Medical Case Reports. 2015; 3(8):265-268. doi: 10.12691/ajmcr-3-8-11

Abstract

Primary splenic diffuse large B cell lymphoma is rarely clinical entity and comprises 1% of all malignant lymphomas. The spleen is also involved in immune defense against blood-borne antigens. Though the haematological malignancies, spleen is usually affected as a part of multisystemic involvement rather than isolated involvement. More than half of patients affected by Hodgkin's disease and about a third of those with non-Hodgkin lymphoma have splenic involvement. The involved spleen may be complicated with rupture due to massive splenomegaly, which may need urgent intervention. In this report, we present a 47-year-old female patient with massive splenomegaly, who was diagnosed with primary splenic diffuse large B cell lymphoma after splenectomy.

Keywords:
diffuse large B-cell lymphoma splenomegaly splenic neoplasms

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