American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2015, 3(7), 205-208
DOI: 10.12691/ajmcr-3-7-6
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Metastatic Nonfunctional Pancreatic Neuroendocrine Tumor – Case Report and Review of the Literature

Ludmila Tankova1, Vanya Gerova1, Plamen Getsov2, Radislav Nakov1, , Stanislav Churchev1, Ivan Terziev3, Irena Kostadinova4, Miroslava Vitkova1, Ventsislav Nakov1, Damyan Damyanov1 and Nina Topuzanska1

1Clinical Center of Gastroenterology, University Hospital, “Queen Joanna”, Sofia, Bulgaria

2Department of Radiology, University Hospital, “Queen Joanna”, Sofia, Bulgaria

3Department of Pathology, University Hospital, “Queen Joanna”, Sofia, Bulgaria

4Medical University, Central Laboratory of Nuclear Medicine, Sofia, Bulgaria

Pub. Date: June 10, 2015

Cite this paper:
Ludmila Tankova, Vanya Gerova, Plamen Getsov, Radislav Nakov, Stanislav Churchev, Ivan Terziev, Irena Kostadinova, Miroslava Vitkova, Ventsislav Nakov, Damyan Damyanov and Nina Topuzanska. Metastatic Nonfunctional Pancreatic Neuroendocrine Tumor – Case Report and Review of the Literature. American Journal of Medical Case Reports. 2015; 3(7):205-208. doi: 10.12691/ajmcr-3-7-6


We present a 56-year-old patient with liver metastases from nonfunctional pancreatic neuroendocrine tumor. The disease is found incidentally in a patient with nonspecific symptoms. Conventional abdominal ultrasound establishes several liver lesions mimicking hemangiomas. On contrast enhancement ultrasonography hypervascularized secondary liver lesions are detected. Subsequent imaging methods and biochemical tests diagnose a pancreatic neuroendocrine metastatic tumor. Left-sided pancreatectomy with splenectomy is carried out. The patient is in good general condition six months after initiation of combination therapy with everolimus and sandostatin LAR depot. Tc-99m-tektrotyd single photon emission computed tomography-CT hybrid imaging shows reduced accumulation of the radiopharmaceutical in the liver parenchyma without data of pancreatic tumor.

neuroendocrine tumor pancreas liver metastases imaging methods

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