American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
Open Access
Journal Browser
American Journal of Medical Case Reports. 2015, 3(4), 113-116
DOI: 10.12691/ajmcr-3-4-8
Open AccessCase Report

Melanocytoma of Optic Disc: Clinical Manifestations, Imaging Characteristics and Follow Up

Rajan Paul1, , Manoj Kulshrestha1, S. Shanmugalingam1 and Dai Barr1

1Aberystwyth Eye Centre, Hywel Dda University Health Board, Aberystwyth, United Kingdom

Pub. Date: April 08, 2015

Cite this paper:
Rajan Paul, Manoj Kulshrestha, S. Shanmugalingam and Dai Barr. Melanocytoma of Optic Disc: Clinical Manifestations, Imaging Characteristics and Follow Up. American Journal of Medical Case Reports. 2015; 3(4):113-116. doi: 10.12691/ajmcr-3-4-8


Melanocytoma of the Optic nerve head, is a benign, stationary pigmented tumor present on or adjacent to the optic disc. Rarely it exhibits minor enlargement and can also undergo malignant transformation to a melanoma. Histopathologically a melanocytoma consists of intensely pigmented round to oval nevus cells with benign features. We report a case of a 77 year old lady with an Optic nerve head melanoma. The clinical features and the imaging characteristics including Ultrasound, Fluorescein angiography and Magnetic resonance imaging are presented.

melanocytoma optic nerve head magnocellular naevus

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit


[1]  Juarez CP, Tso MO. An ultrastructural study of melanocytomas (magnocellular nevi) of the optic disk and uvea. Am J Ophthalmol. 1980 Jul; 90(1):48-62.
[2]  Zimmerman LE, Garron LK. Melanocytoma of the optic disc. Int Ophthalmol Clinic 1962;431-440.
[3]  Cogan DG.Discussion; pigmented ocular tumors. En: Boniuk M., editors. Ocular and adnexal tumors. New and controversial aspects. St. Louis: CV Mosby Co.; 1964. 385.
[4]  Sehu KW, Lee WR. Ophthalmic Pathology: An illustrated guide for clinicians; 1st edition. Oxford: Blackwell Publishing; 2005 pp. 255-255.
[5]  Zimmerman LE. Melanocytes, melanocytic nevi, and melanocytoma. Invest Ophthalmol 1965;4:11-41.
[6]  Shields, J. A. et al. Ophthalmology 2004; 111(9):1739-1746.
[7]  Shields JA, Shields CL, Eagle RC, Singh AD, Berrocal MH, Berrocal JA. Central retinal vascular obstruction secondary to melanocytoma of the optic disc. Arch Ophthalmol 2001; 119: 129-33.
[8]  Usui T, Shirakashi M, Kurosawa A, Abe H, Iwata K. Visual disturbance in patients with melanocytoma of the optic disc. Opthalmologica 1990; 201: 92-8.
[9]  Saba Al-Rashaed, Emad B. Abboud, and Sawsan R. Nowilaty. Characteristics of Optic Disc Melanocytomas Presenting with Visual Dysfunction. Middle East Afr J Ophthalmol. 2010 Jul-Sep; 17(3): 242–245.
[10]  Lee CS1, Bae JH, Jeon IH, Byeon SH, Koh HJ, Lee SC Melanocytoma of the optic disk in the Korean population. Retina. 2010 Nov-Dec; 30(10):1714-20.