American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2015, 3(4), 111-112
DOI: 10.12691/ajmcr-3-4-7
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A Case of Acute Myeloid Leukemia with Bilateral Leukemic Optic Nerve Infiltration

Yıldırım Rahşan1, Urlu Selin Merih2, Sincan Gülden1, , Kaban Göktürk2, Karaman Adem3 and Bilen Yusuf1

1Atatürk University, School of Medicine, Departments of Haematology, Erzurum, TURKEY

2Atatürk University, School of Medicine, Departments of Internal Medicine, Erzurum, TURKEY

3Atatürk University, School of Medicine, Departments of Radiology, Erzurum, TURKEY

Pub. Date: March 20, 2015

Cite this paper:
Yıldırım Rahşan, Urlu Selin Merih, Sincan Gülden, Kaban Göktürk, Karaman Adem and Bilen Yusuf. A Case of Acute Myeloid Leukemia with Bilateral Leukemic Optic Nerve Infiltration. American Journal of Medical Case Reports. 2015; 3(4):111-112. doi: 10.12691/ajmcr-3-4-7


Ocular involvement in patients with leukemia may be due to various reasons and it is characterized by various clinical symptoms. Ocular problems in patients who have acute myeloid leukaemia (AML) are commonly observed. Orbital and ocular lesions carry a poor prognosis in patients with acute myeloid leukemia. Direct invasion of the retina and choroid with the neoplastic cells is common, but the involvement of the optic nerve, uveal tract are relatively rare. Ocular symptoms include blurred vision and diplopia due to the involvement of optic nerves. This paper reports a 68 year old patient with AML. 5 azasitidin was initiated for treatment. By the second cycle, he complained of vision loss for right eye. These findings occured for left eye after three days. Optic nerve involvement was found with orbital magnetic resonance imaging with contrast. We report these patient because of rarity.

acute myeloid leukemia diplopia optic nerve infiltration vision loss

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