American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: http://www.sciepub.com/journal/ajmcr Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2015, 3(2), 42-45
DOI: 10.12691/ajmcr-3-2-7
Open AccessCase Report

Unexpected Acute Myocardial Infarction Due to Disseminated Intravascular Coagulation

Motoharu Shibusawa1, , Takaaki Matsumura2, Hisashi Tsutsumi1, Yuuji Itou3 and Yoshiaki Shibata2

1Department of Hematology Medicine, Tokyo Metropolitan Health and Medical Treatment Corporation, Tama-Hokubu Medical Center, Tokyo, Japan

2Department of Gastrointestinal Medicine, Tokyo Metropolitan Health and Medical Treatment Corporation, Tama-Hokubu Medical Center, Tokyo, Japan

3Department of Pathology, Tokyo Metropolitan Health and Medical Treatment Corporation, Tama-Hokubu Medical Center, Tokyo, Japan

Pub. Date: January 23, 2015

Cite this paper:
Motoharu Shibusawa, Takaaki Matsumura, Hisashi Tsutsumi, Yuuji Itou and Yoshiaki Shibata. Unexpected Acute Myocardial Infarction Due to Disseminated Intravascular Coagulation. American Journal of Medical Case Reports. 2015; 3(2):42-45. doi: 10.12691/ajmcr-3-2-7

Abstract

An autopsy case of gastric cancer accompanied by disseminated intravascular coagulation (DIC) that resulted in unexpected acute myocardial infarction (AMI) is reported. A 66-year-old man was introduced to our hospital and was diagnosed with gastric cancer accompanied by bone marrow carcinomatosis with DIC. On the fourteenth day of admission, he experienced dyspnea. He died on the fifteenth day. An autopsy was performed. The autopsy findings revealed myocardial infarction from the lateral to anterior and posterior ventricular walls, thromboembolism in the right coronary artery, and nonbacterial thrombogenic carditis of the mitral valve. A diagnosis of AMI was made by the autopsy findings. In cases accompanied by DIC, thrombus may develop in coronary arteries, resulting in AMI. In these patients, the typical symptoms of AMI and ST-segment elevation and pathologic Q waves on electrocardiogram are often not observed. The importance of this phenomenon warrants consideration in clinical practice.

Keywords:
disseminated intravascular coagulation acute myocardial infarction

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References:

[1]  George J N. Systemic malignancies as a cause of unexpected microangiopathic hemolytic anemia and thrombocytopenia. Oncology (Williston Park). 2011; 25 (10): 908-14.
 
[2]  Kusumoto H, Haraguchi M, Nozuka Y, Oda Y, Tsuneyoshi M and Iguchi H. Characteristic features of disseminated carcinomatosis of the bone marrow due to gastric cancer: the pathogenesis of bone destruction. Oncol Rep. 2006; 16 (4): 735-40.
 
[3]  Levi M, Toh C H, Thachil J and Watson H G. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol. 2009; 145 (1): 24-33.
 
[4]  Levi M and Seligsphn U, Disseminated intravascular coagulation. In: Kaushanky K, ed. Williams Hematology Eighth edition, USA: The McGraw-Hill Companies, 2010: 2101.
 
[5]  Rhee J, Han S W, Oh D Y, Im S A, Kim T Y and Bang Y J. Clinicopathologic features and clinical outcomes of gastric cancer that initially presents with disseminated intravascular coagulation: a retrospective study. J Gastroenterol Hepatol. 2010; 25 (9): 1537-42.
 
[6]  Ueda K, Sugiura M, Ohkawa S, Hiraoka K, Mifune J, Matsuda T and Murakami M. Disseminated intravascular coagulation in the aged complicated by acute myocardial infarction. Jpn J Med. 1981; 20 (3): 202-10.
 
[7]  Kim K H, Jeong M H, Chung I J, Cho J G, Song T B, Park J C and Kang J C. A case of septic shock and disseminated intravascular coagulation complicated by acute myocardial infarction following amniocentesis. Korean J Intern Med. 2005; 20 (4): 325-9.
 
[8]  Yamaguchi M, Murata R, Mizutani T, Kawamura Y and Ueda M. [Acute myelogenous leukemia associated with disseminated intravascular coagulation and acute myocardial infarction at relapse]. Rinsho Ketsueki. 2001; 42 (9): 716-8.
 
[9]  Yamauchi T, Yamamoto S, Fukumoto M, Oyama N, Nakano A, Nakayama T, Iwasaki H, Shimizu H, Tsutani H, Lee J D, Okada K and Ueda T. [Early manifestation of septic shock and disseminated intravascular coagulation complicated by acute myocardial infarction in a patient suspected of having Legionnaires' disease]. Kansenshogaku Zasshi. 1998; 72 (3): 286-92.