American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2015, 3(2), 27-29
DOI: 10.12691/ajmcr-3-2-1
Open AccessCase Report

The Corpus Callosum Agenesis: A Case Report

Derbali F1, , Ben Fradj F2, Rezgui A2, Karmani M2, Hajji R1, Ben Abdallah O2, Mzabi A2 and Laouani C2

1Internal Medicine Department - SidiBouzid Regional Hospital –SidiBouzid - Tunisia

2Internal Medicine Department - Sousse University Hospital – Sousse - Tunisia

Pub. Date: January 18, 2015

Cite this paper:
Derbali F, Ben Fradj F, Rezgui A, Karmani M, Hajji R, Ben Abdallah O, Mzabi A and Laouani C. The Corpus Callosum Agenesis: A Case Report. American Journal of Medical Case Reports. 2015; 3(2):27-29. doi: 10.12691/ajmcr-3-2-1


Agenesis of corpus callosum is the most frequent cerebral malformations. Diagnosis is based on brain imaging. It is most often asymptomatic. Hyperhidrosis can be part of his clinical picture. We present the case of a 49 year old patient, unemployed, with a history of frontal lobe epilepsy and extra pyramidal syndrome. He consulted for a left hemiparesis with sweating attacks. Physical examination showed facial dysmorphism, psychomotor retardation, hemiparesis predominantly left brachiocephalic and bilateral pyramidal syndrome. Brain imaging showed, in addition to cerebral ischemia, a corpus callosum agenesis. This observation helped to highlight a rare disease whose clinical presentation is nonspecific. This malformation is to seek at prenatal, postnatal and even at the adulthood. Hyperhidrosis attacks without obvious underlying pathology should suggest this diagnosis.

corpus callosumage nesis hyperhidrosis brain malformations epilepsy brainimaging

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