American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2014, 2(9), 175-180
DOI: 10.12691/ajmcr-2-9-4
Open AccessCase Report

Protein S Deficiency Related Retinal Artery Occlusion in a Pregnant Chinese Woman

Syed Shoeb Ahmad1, , Shuaibah Abdul Ghani1 and Lindfay Laura Lau1

1Ophthalmology Department, Queen Elizabeth Hospital, Kota Kinabalu, Malaysia

Pub. Date: September 10, 2014

Cite this paper:
Syed Shoeb Ahmad, Shuaibah Abdul Ghani and Lindfay Laura Lau. Protein S Deficiency Related Retinal Artery Occlusion in a Pregnant Chinese Woman. American Journal of Medical Case Reports. 2014; 2(9):175-180. doi: 10.12691/ajmcr-2-9-4


Purpose: To report a case of branch retinal artery occlusion (BRAO) in a pregnant patient of Chinese descent found to have Protein S deficiency. Case report: A 35 year-old apparently healthy, pregnant female of Chinese origin reported in the eye clinic of our hospital with a complaint of sudden appearance of a “shadow” in the periphery of her left eye for the last three days. On examination, she was found to have a BRAO in that eye. A number of laboratory, radiological and systemic examinations were done to find out the cause of the occlusion. However, a deficiency of Protein S was the only abnormality found. So far there have been only a few cases reported concerning this hematological deficiency causing a BRAO. This case report describes the events leading to the diagnosis of this rare condition. Conclusion: In cases of BRAO, especially in young patients it is important to rule out Protein S deficiency which may have life-threatening consequences.

Protein S deficiency retinal artery occlusion pregnancy

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