American Journal of Medical Case Reports
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American Journal of Medical Case Reports. 2022, 10(3), 51-55
DOI: 10.12691/ajmcr-10-3-3
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Pregnant Patient with Severe COVID-19 Pneumonia Treated by Intensive Immune Suppression Therapy during the Omicron (B.1.1.529) Variant Outbreak: A Successfully Treated Case

Michika Hamada1, Youichi Yanagawa1, , Satomi Tanaka2, Hiromichi Ohasaka1, Kei Jitsuiki1 and Kouhei Ishikawa1

1Department of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University

2Department of Obstetrics, Shizuoka Hospital, Juntendo University

Pub. Date: March 11, 2022

Cite this paper:
Michika Hamada, Youichi Yanagawa, Satomi Tanaka, Hiromichi Ohasaka, Kei Jitsuiki and Kouhei Ishikawa. Pregnant Patient with Severe COVID-19 Pneumonia Treated by Intensive Immune Suppression Therapy during the Omicron (B.1.1.529) Variant Outbreak: A Successfully Treated Case. American Journal of Medical Case Reports. 2022; 10(3):51-55. doi: 10.12691/ajmcr-10-3-3


A 35-year-old pregnant woman (gestational age, 35 weeks) developed general fatigue, headache, and joint pain following the onset fever, cough, and nasal discharge after the outbreak of the Omicron variant in Japan. The patient had obesity (body mass index, 41), depression and gestational diabetes mellitus, which was treated with insulin. On the 8th day after the onset of initial flu-like symptoms, she was admitted to our hospital because polymerase chain reaction for COVID-19 became positive. Initially, her vital signs were stable without any oxygen demand. On day 11, she required oxygen therapy (4 L/min). Chest computed tomography (CT) showed multiple bilateral centrilobular patch consolidations with several subpleural lesions. As she had multiple risk factors for acute respiratory distress syndrome (ARDS), she underwent emergency cesarean section and immune modulation therapy was initiated. After the operation, her oxygenation deteriorated and she underwent tracheal intubation and mechanical ventilation on day 13. After multimodal therapy, her lung function improved and she was extubated on day 16. After rehabilitation and baby care training, she was discharged on day 27 without sequelae. This is the case of a pregnant woman with severe COVID-19 pneumonia who was successfully treated by emergency cesarean section, intensive immune suppression therapy and mechanical ventilation during the Omicron variant outbreak in Japan. The present case suggests that even pregnant women should receive COVID-19 vaccination to avoid the onset of ARDS, a potentially fatal condition.

COVID-19 omicron variant steroid pulse pregnant

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